Reactome | ACIN1 [nucleoplasm]

ACIN1 [nucleoplasm]

Stable Identifier

R-HSA-9770238

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Apoptotic chromatin condensation inducer in the nucleus, ACINU_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9UKV3 ACIN1

Gene Names

ACIN1, ACINUS, KIAA0670

Chain

chain:1-1341

Reference Genes

BioGPS Gene:22985 ACIN1

COSMIC (genes):ACIN1 ACIN1

CTD Gene:22985 ACIN1

dbSNP Gene:22985 ACIN1

ENSEMBL:ENSG00000100813 ACIN1

HGNC:17066 ACIN1

KEGG:hsa:22985 ACIN1

Monarch:22985 ACIN1

NCBI Gene:22985 ACIN1

OMIM:604562 ACIN1

UCSC:Q9UKV3 ACIN1

Reference Transcript

Other Identifiers

11716673_a_at

11716674_a_at

11750382_a_at

16790693

201715_PM_s_at

201715_s_at

22985

33398_at

3557097

3557098

3557099

3557100

3557101

3557102

3557103

3557105

3557107

3557108

3557109

3557110

3557111

3557112

3557113

3557114

3557115

3557116

3557117

3557118

3557119

3557120

3557121

3557122

3557123

3557124

3557125

3557126

3557127

3557128

3557130

3557131

3557132

3557133

3557134

3557135

3557136

3557137

3557138

3557139

3557140

3557141

3557142

3557143

3557144

3557147

3557148

3557149

3557150

3557151

3557152

3557153

3557154

3557157

3557160

3557162

3557164

3557165

3557166

3557167

3557168

7977906

A_23_P14389

GE61557

GO:0003676

GO:0003723

GO:0003824

GO:0005515

GO:0005634

GO:0005654

GO:0005730

GO:0005829

GO:0005886

GO:0006397

GO:0006915

GO:0008380

GO:0012501

GO:0016071

GO:0016607

GO:0016787

GO:0016887

GO:0019899

GO:0030154

GO:0030218

GO:0030263

GO:0035145

GO:0043065

GO:0043226

GO:0045657

GO:0048025

GO:0061574

HMNXSV003006067

HMNXSV003021341

HMNXSV003035964

ILMN_1699636

PH_hs_0012649

TC14000948.hg

g7662237_3p_a_at

Participates

as a component of

ASAP complex [nucleoplasm] (Homo sapiens)

Other forms of this molecule

ACIN1 [cytosol]

ACIN1(1094-1341) [cytosol]

ACIN1(1-1093) [cytosol]

Inferred To

ACIN1 [nucleoplasm] (Bos taurus)

ACIN1 [nucleoplasm] (Canis familiaris)

Acin1 [nucleoplasm] (Mus musculus)

Acin1 [nucleoplasm] (Rattus norvegicus)

Acn [nucleoplasm] (Drosophila melanogaster)

acin-1 [nucleoplasm] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001158286.1, NP_001158288.1, XP_005267475.1, NP_001158287.1, NP_001158289.1, NP_055792.1

ENSEMBL

ENST00000555053, ENST00000262710, ENSP00000350073, ENSP00000451328, ENSP00000380502, ENST00000357481, ENSP00000262710, ENST00000338631, ENSP00000345541, ENST00000397341

OpenTargets

ENSG00000100813

HPA

ENSG00000100813-ACIN1

PRO

Q9UKV3

Pharos - Targets

Q9UKV3

GlyGen

Q9UKV3

PDB

6G6S

Interactors (28)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9H307 PNN	1	PNN [nucleoplasm] (R-HSA-9770779)	0.669	3
UniProt:P78362 SRPK2	1	SRPK2 [cytosol] (R-HSA-9729332)	0.659	3
UniProt:Q96SB4 SRPK1	2	SRPK1 [nucleoplasm] (R-HSA-9821984) SRPK1 [cytosol] (R-HSA-9729349)	0.643	3
UniProt:P26368 U2AF2	2	U2AF2 [nucleoplasm] (R-HSA-71987) 5OHK15,276-U2AF2 [nucleoplasm] (R-HSA-9630011)	0.615	5
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.589	2
UniProt:P31946 YWHAB	1	YWHAB [cytosol] (R-HSA-48888)	0.589	2
UniProt:Q15428 SF3A2	1	SF3A2 [nucleoplasm] (R-HSA-71964)	0.564	2
UniProt:Q15287 RNPS1	2	RNPS1 [cytosol] (R-HSA-159256) RNPS1 [nucleoplasm] (R-HSA-156778)	0.547	3
UniProt:P48426 PIP4K2A	2	PIP4K2A [cytosol] (R-HSA-1604641) PIP4K2A [nucleoplasm] (R-HSA-6811484)	0.527	2
UniProt:Q9Y519 T184B			0.527	2
UniProt:Q53F19 NCBP3			0.527	4
UniProt:Q9Y2J2 EPB41L3	1	EPB41L3 [cytosol] (R-HSA-6797563)	0.527	3
UniProt:P49760 CLK2			0.527	2
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.527	3
UniProt:Q8TAD8 SNIP1	1	SNIP1 [nucleoplasm] (R-HSA-3222315)	0.527	2
UniProt:Q8NCB2 CAMKV			0.527	2
UniProt:P09661 SNRPA1	1	SNRPA1 [nucleoplasm] (R-HSA-71958)	0.527	2
UniProt:Q9Y383 LC7L2			0.527	3
UniProt:P82979 SARNP	1	SARNP [nucleoplasm] (R-HSA-8849146)	0.527	2
UniProt:Q9Y581 INSL6			0.527	2
UniProt:O43491 EPB41L2	1	EPB41L2 [cytosol] (R-HSA-6797548)	0.527	3
UniProt:P49761 CLK3			0.527	2
UniProt:Q01081 U2AF1	1	U2AF1 [nucleoplasm] (R-HSA-71985)	0.527	2
UniProt:Q9UEU0 VTI1B	2	VTI1B [extracellular region] (R-HSA-8862983) VTI1B [platelet alpha granule lumen] (R-HSA-8862964)	0.527	2
UniProt:Q9NYS7 WSB2	1	WSB2 [cytosol] (R-HSA-8863349)	0.527	2
UniProt:P61457 PCBD1	1	PCBD1 [cytosol] (R-HSA-71131)	0.524	2
UniProt:P09651 HNRNPA1	2	HNRNPA1 [nucleoplasm] (R-HSA-71927) HNRNPA1 [cytosol] (R-HSA-9727902)	0.483	2
UniProt:Q9BZZ5 API5			0.463	2