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IK [nucleoplasm]
Stable Identifier
R-HSA-9770239
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
fullName evidence="9"Protein Red, RED_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
mRNA Splicing (Homo sapiens)
mRNA Splicing - Major Pathway (Homo sapiens)
Formation of the Spliceosomal B complex (Homo sapiens)
Spliceosomal B complex [nucleoplasm] (Homo sapiens)
IK [nucleoplasm] (Homo sapiens)
Spliceosomal Pre-B complex [nucleoplasm] (Homo sapiens)
IK [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal Bact complex (Homo sapiens)
IK [nucleoplasm] (Homo sapiens)
Spliceosomal B complex [nucleoplasm] (Homo sapiens)
IK [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal Pre-B complex (Homo sapiens)
IK [nucleoplasm] (Homo sapiens)
Spliceosomal Pre-B complex [nucleoplasm] (Homo sapiens)
IK [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13123 IK
Gene Names
IK, RED, RER
Chain
chain:1-557
Reference Genes
BioGPS Gene:3550 IK
COSMIC (genes):IK IK
CTD Gene:3550 IK
dbSNP Gene:3550 IK
ENSEMBL:ENSG00000113141 IK
ENSEMBL_homo_sapiens_GENE:ENSG00000113141.19 IK
HGNC:5958 IK
KEGG Gene (Homo sapiens):3550 IK
Monarch:3550 IK
NCBI Gene:3550 IK
OMIM:600549 IK
UCSC:Q13123 IK
Reference Transcript
RefSeq:NM_006083.3 IK
Other Identifiers
11743487_a_at
11743488_x_at
11751009_s_at
11751010_x_at
16990119
18670142
18670143
18670144
18670145
18670146
18670147
18670148
18670149
18670150
18670152
18670154
18670155
18670157
18678263
200066_PM_at
200066_at
218_at
2554529
2831935
2831937
2831938
2831940
2831941
2831942
2831946
2831947
2831949
2831951
2831955
2831956
2831957
2831960
2831962
2831964
2831965
2831966
2831968
2831969
3550
38046_at
7892745
7893550
7893561
7893788
7894010
7894104
7894158
7894557
7894617
7894675
7894708
7894796
7895067
7895948
7896029
7896076
7896085
7896112
7896483
8108568
87819_at
A_14_P130603
A_23_P133245
A_32_P29759
GE55160
GO:0000228
GO:0000278
GO:0000398
GO:0000922
GO:0005515
GO:0005634
GO:0005654
GO:0005681
GO:0005694
GO:0005737
GO:0005856
GO:0006397
GO:0007059
GO:0007094
GO:0008380
GO:0016071
GO:0016607
GO:0023052
GO:0034501
GO:0042802
GO:0043226
GO:0071005
GO:0097431
GO:0140014
HMNXSV003014305
HMNXSV003020875
ILMN_1699362
PH_hs_0028387
S74221_at
TC05000730.hg
g5901877_3p_at
Participates
as an output of
Formation of the Spliceosomal Bact complex (Homo sapiens)
as a component of
Spliceosomal B complex [nucleoplasm] (Homo sapiens)
Spliceosomal Pre-B complex [nucleoplasm] (Homo sapiens)
as an input of
Formation of the Spliceosomal Pre-B complex (Homo sapiens)
Inferred To
Ghost homologue of IK [nucleoplasm]
(Schizosaccharomyces pombe)
IK [nucleoplasm]
(Bos taurus)
IK [nucleoplasm]
(Canis familiaris)
IK [nucleoplasm]
(Dictyostelium discoideum)
IK [nucleoplasm]
(Gallus gallus)
IK [nucleoplasm]
(Plasmodium falciparum)
IK [nucleoplasm]
(Sus scrofa)
beag [nucleoplasm]
(Drosophila melanogaster)
Ik [nucleoplasm]
(Mus musculus)
Ik [nucleoplasm]
(Rattus norvegicus)
ik [nucleoplasm]
(Xenopus tropicalis)
smu-2 [nucleoplasm]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_006074.2
OpenTargets
ENSG00000113141
HPA
ENSG00000113141-IK
GeneCards
Q13123
ZINC target
Q13123
Ensembl
ENST00000417647
,
ENSG00000113141
,
ENSP00000396301
PRO
Q13123
Pharos - Targets
Q13123
PDB
6Q8I
,
5O9Z
Interactors (24)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q2TAY7 SMU1
1
SMU1 [nucleoplasm]
(R-HSA-9770259)
0.829
7
UniProt:P04618 rev
3
REV (P04618) protein [extracellular region]
(R-HIV-174998)
REV (P04618) protein [nucleoplasm]
(R-HIV-175380)
REV (P04618) protein [cytosol]
(R-HIV-173267)
0.558
3
UniProt:Q00403 GTF2B
1
GTF2B [nucleoplasm]
(R-HSA-65888)
0.556
3
UniProt:P47897 QARS1
2
QARS [cytosol]
(R-HSA-379615)
QARS [mitochondrial matrix]
(R-HSA-379592)
0.556
3
UniProt:Q01658 DR1
1
DR1 [nucleoplasm]
(R-HSA-3662280)
0.556
3
UniProt:Q96CV9 OPTN
5
OPTN [recycling endosome membrane]
(R-HSA-8854141)
OPTN [Golgi membrane]
(R-HSA-2161111)
p-S177-OPTN [nucleoplasm]
(R-HSA-2562595)
p-S177-OPTN [cytosol]
(R-HSA-2562525)
OPTN [cytosol]
(R-HSA-9687907)
0.556
3
UniProt:P02545 LMNA
3
LMNA(1-646) [nuclear envelope]
(R-HSA-535479)
LMNA(1-567)-RAF1(279-648) fusion [cytosol]
(R-HSA-6802399)
LMNA(1-567)-p-RAF1(279-648) fusion [cytosol]
(R-HSA-6802537)
0.556
3
UniProt:O75190 DNAJB6
2
DNAJB6 [cytosol]
(R-HSA-5252014)
DNAJB6 [nucleoplasm]
(R-HSA-5255425)
0.556
3
UniProt:Q9H6Z9 EGLN3
2
EGLN3 [nucleoplasm]
(R-HSA-1234104)
EGLN3 [cytosol]
(R-HSA-1234115)
0.556
3
UniProt:Q8NHQ1 CEP70
1
CEP70 [cytosol]
(R-HSA-380257)
0.556
3
UniProt:O95983-2 MBD3
0.556
3
UniProt:P26196 DDX6
1
DDX6 [cytosol]
(R-HSA-430032)
0.556
3
UniProt:Q7Z699 SPRED1
2
SPRED1 [plasma membrane]
(R-HSA-5658225)
SPRED1 [cytosol]
(R-HSA-5654207)
0.556
3
UniProt:O14965 AURKA
6
SUMO1-K258-AURKA [cytosol]
(R-HSA-4655367)
PolyUb-AURKA [cytosol]
(R-HSA-8854040)
p-T288-AURKA [nucleoplasm]
(R-HSA-6805089)
AURKA [nucleoplasm]
(R-HSA-4655443)
AURKA [cytosol]
(R-HSA-174254)
p-T288-AURKA [cytosol]
(R-HSA-2574832)
0.524
3
UniProt:Q8TAD8 SNIP1
1
SNIP1 [nucleoplasm]
(R-HSA-3222315)
0.508
2
UniProt:Q13123 IK
1
IK [nucleoplasm]
(R-HSA-9770239)
0.508
2
UniProt:Q96NB3 ZNF830
1
ZNF830 [nucleoplasm]
(R-HSA-6781962)
0.508
2
UniProt:P55081 MFAP1
1
MFAP1 [nucleoplasm]
(R-HSA-2396419)
0.508
2
UniProt:O15541 RNF113A
1
RNF113A [nucleoplasm]
(R-HSA-9769563)
0.508
2
UniProt:O94906 PRPF6
1
PRPF6 [nucleoplasm]
(R-HSA-71881)
0.508
2
UniProt:Q70Z53 F10C1
0.508
2
UniProt:Q9HCS7 XAB2
1
XAB2 [nucleoplasm]
(R-HSA-67411)
0.508
2
UniProt:Q15029 EFTUD2
1
EFTUD2 [nucleoplasm]
(R-HSA-71883)
0.508
2
UniProt:P98175 RBM10
1
RBM10 [nucleoplasm]
(R-HSA-9770262)
0.508
2
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