Reactome | CWF19L2 [nucleoplasm]

CWF19L2 [nucleoplasm]

Stable Identifier

R-HSA-9770846

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

CWF19-like protein 2, C19L2_HUMAN

Locations in the PathwayBrowser for interactor UniProt:P14373 TRIM27

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External Reference Information

External Reference

UniProt:Q2TBE0 CWF19L2

Gene Names

CWF19L2

Chain

chain:1-894

Reference Genes

BioGPS Gene:143884 CWF19L2

COSMIC (genes):CWF19L2 CWF19L2

CTD Gene:143884 CWF19L2

dbSNP Gene:143884 CWF19L2

ENSEMBL:ENSG00000152404 CWF19L2

ENSEMBL:ENSG00000152404.16 CWF19L2

HGNC:26508 CWF19L2

KEGG Gene (Homo sapiens):143884 CWF19L2

Monarch:143884 CWF19L2

NCBI Gene:143884 CWF19L2

UCSC:Q2TBE0 CWF19L2

Reference Transcript

RefSeq:NM_152434.2 CWF19L2

Other Identifiers

11724822_a_at

11724823_s_at

11752229_a_at

143884

16743994

228916_PM_at

228916_at

237040_PM_at

237040_at

3389788

3389789

3389790

3389791

3389792

3389793

3389796

3389797

3389798

3389799

3389800

3389807

3389808

3389810

3389811

3389813

3389821

3389823

3389831

3389833

3389834

3389837

3389838

3389839

3389840

3389842

3389844

3389846

64155_at

7951447

81897_at

A_23_P161719

GE79905

GO:0000398

GO:0005515

GO:0005634

GO:0005654

GO:0016071

GO:0043226

GO:0071014

HMNXSV003031036

Hs.160699.0.A1_3p_at

Hs.24380.0.A1_3p_at

ILMN_1668498

PH_hs_0002146

TC11002259.hg

Participates

as an output of

Disassembly of the Intron Lariat Spliceosome (new) (Homo sapiens)

as a component of

Intron Lariat Spliceosome (ILS) [nucleoplasm] (Homo sapiens)

as an input of

Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) (Homo sapiens)

Inferred To

cwf19 [nucleoplasm] (Schizosaccharomyces pombe)

CWF19L2 [nucleoplasm] (Bos taurus)

CWF19L2 [nucleoplasm] (Caenorhabditis elegans)

CWF19L2 [nucleoplasm] (Canis familiaris)

CWF19L2 [nucleoplasm] (Dictyostelium discoideum)

CWF19L2 [nucleoplasm] (Drosophila melanogaster)

CWF19L2 [nucleoplasm] (Gallus gallus)

CWF19L2 [nucleoplasm] (Plasmodium falciparum)

CWF19L2 [nucleoplasm] (Sus scrofa)

Cwf19l2 [nucleoplasm] (Mus musculus)

Cwf19l2 [nucleoplasm] (Rattus norvegicus)

cwf19l2 [nucleoplasm] (Danio rerio)

cwf19l2 [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

NP_689647.2

OpenTargets

ENSG00000152404

GeneCards

Q2TBE0

HPA

ENSG00000152404-CWF19L2

Ensembl

ENSG00000152404, ENST00000282251, ENSP00000282251

PRO

Q2TBE0

Pharos - Targets

Q2TBE0

PDB

6ID1, 6ID0

Interactors (82)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9Y6D9 MAD1L1	1	MAD1L1 [cytosol] (R-HSA-141433)	0.718	6
UniProt:Q15427 SF3B4	1	SF3B4 [nucleoplasm] (R-HSA-71975)	0.718	6
UniProt:Q15742 NAB2	1	NAB2 [nucleoplasm] (R-HSA-9612177)	0.718	6
UniProt:P50221 MEOX1			0.718	6
UniProt:Q9BYV2 TRI54			0.718	6
UniProt:P14373 TRIM27	2	TRIM27 [nucleoplasm] (R-HSA-2997690) TRIM27 [cytosol] (R-HSA-8851002)	0.718	6
UniProt:Q6NUQ1 RINT1	1	RINT1 [cytosol] (R-HSA-6810991)	0.718	6
UniProt:P14136 GFAP	3	p-GFAP [lysosomal membrane] (R-HSA-9626054) GFAP [lysosomal membrane] (R-HSA-9625195) GFAP [cytosol] (R-HSA-1253311)	0.718	6
UniProt:Q9P1Z2 CACO1			0.718	6
UniProt:O94972 TRIM37	1	TRIM37 [cytosol] (R-HSA-976049)	0.718	6
UniProt:Q9C026 TRIM9	1	TRIM9 [cytosol] (R-HSA-976054)	0.718	6
UniProt:Q8IYI6 EXOC8	2	EXOC8 [plasma membrane] (R-HSA-264948) EXOC8 [cytosol] (R-HSA-5623388)	0.556	3
UniProt:Q9Y250 LZTS1			0.556	3
UniProt:Q9NQ69 LHX9	1	LHX9 [nucleoplasm] (R-HSA-9011158)	0.556	3
UniProt:P51114-2 FXR1			0.556	3
UniProt:Q8NHQ1 CEP70	1	CEP70 [cytosol] (R-HSA-380257)	0.556	3
UniProt:Q5T7B8-2 KIF24			0.556	3
UniProt:Q9H0C1 ZMY12			0.556	3
UniProt:Q96MT8-3 CEP63			0.556	3
UniProt:Q9BYV9 BACH2			0.556	3
UniProt:Q8TC57 M1AP			0.556	3
UniProt:Q8N137 CNTRB			0.556	3
UniProt:P17661 DES	1	DES [cytosol] (R-HSA-390570)	0.556	3
UniProt:Q9H257-2 CARD9			0.556	3
UniProt:Q9UBR4-2 LHX3			0.556	3
UniProt:Q13573 SNW1	1	SNW1 [nucleoplasm] (R-HSA-351663)	0.556	3
UniProt:Q9GZM8 NDEL1	1	NDEL1 [cytosol] (R-HSA-376258)	0.556	3
UniProt:Q13137 CACO2			0.556	3
UniProt:Q4G0R1 Q4G0R1			0.556	3
UniProt:P08670 VIM	11	VIM(2-85) [cytosol] (R-HSA-350264) VIM(86-466) [cytosol] (R-HSA-350294) VIM(430-466) [cytosol] (R-HSA-350316) VIM(2-429) [cytosol] (R-HSA-350317) VIM(260-466) [cytosol] (R-HSA-350314) VIM(2-259) [cytosol] (R-HSA-350323) VIM [cytosol] (R-HSA-201600) Vimentin [late endosome lumen] (R-HSA-9660019) Vimentin [microtubule organizing center] (R-HSA-9657898) Vimentin [cytosol] (R-HSA-9646687) Vimentin [lysosomal lumen] (R-HSA-9659977)	0.556	3
UniProt:Q5JR59-3 MTUS2			0.556	3
UniProt:P13682 ZNF35			0.556	3
UniProt:Q9NRI5-2 DISC1			0.556	3
UniProt:Q12933 TRAF2	5	TRAF2 [nucleoplasm] (R-HSA-8862199) K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) TRAF2 [cytosol] (R-HSA-66370)	0.556	3
UniProt:Q8IZU0 FAM9B			0.556	3
UniProt:Q68D86 C102B			0.556	3
UniProt:A0A0C3SFZ9 A0A0C3SFZ9			0.556	3
UniProt:O43586 PSTPIP1	1	PSTPIP1 [cytosol] (R-HSA-879220)	0.556	3
UniProt:Q96BR9 ZBT8A			0.556	3
UniProt:Q96ED9-2 HOOK2			0.556	3
UniProt:Q9NSC5 HOMER3	1	HOMER3 [cytosol] (R-HSA-6794236)	0.556	3
UniProt:Q4V328 GRAP1			0.556	3
UniProt:Q96ED9 HOOK2			0.556	3
UniProt:O75031 HSF2B			0.556	3
UniProt:Q9H257 CARD9	3	CARD9 [cytosol] (R-HSA-561194) p-T231-CARD9 [plasma membrane] (R-HSA-5607623) CARD9 [plasma membrane] (R-HSA-5607662)	0.556	3
UniProt:Q69YN2 C19L1			0.556	3
UniProt:O75558 STX11			0.556	3
UniProt:A6NC98 CC88B			0.556	3
UniProt:Q9BWT7 CAR10			0.556	3
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.556	3
UniProt:Q8TAP6 CEP76	1	CEP76 [cytosol] (R-HSA-380281)	0.556	3
UniProt:Q9UBB4 ATX10			0.556	3
UniProt:Q8N1B4 VPS52	1	VPS52 [trans-Golgi network membrane] (R-HSA-6811029)	0.556	3
UniProt:A1L4K1 FSD2			0.556	3
UniProt:Q13625-3 TP53BP2			0.556	3
UniProt:O94929-2 ABLIM3			0.556	3
UniProt:Q8WXH2 JPH3			0.556	3
UniProt:Q8N6L0 KASH5			0.556	3
UniProt:Q96JN2-2 CCDC136			0.556	3
UniProt:Q63ZY3 KANK2			0.556	3
UniProt:P36406 TRI23			0.556	3
UniProt:Q9UJC3 HOOK1			0.556	3
UniProt:Q5JR59 MTUS2			0.556	3
UniProt:O95995 GAS8	1	GAS8 [cytosol] (R-HSA-5633057)	0.556	3
UniProt:P51116 FXR2			0.556	3
UniProt:A6NEM1 GG6L9			0.556	3
UniProt:Q6A162 KRT40	1	KRT40 [cytosol] (R-HSA-6809605)	0.556	3
UniProt:Q9BVG8-5 KIFC3			0.556	3
UniProt:Q86VP1 TAX1BP1	1	TAX1BP1 [cytosol] (R-HSA-937346)	0.556	3
UniProt:Q5VU43-2 PDE4DIP			0.556	3
UniProt:P48059-3 LIMS1			0.556	3
UniProt:Q86TI0 TBC1D1	2	TBC1D1 [cytoplasmic vesicle membrane] (R-HSA-1454718) p-S237-TBC1D1 [cytosol] (R-HSA-1454673)	0.556	3
UniProt:Q9UBB9 TFIP11	1	TFIP11 [nucleoplasm] (R-HSA-8869310)	0.556	3
UniProt:Q9NRD5 PICK1	2	PICK1 [plasma membrane] (R-HSA-416989) PICK1 [endocytic vesicle membrane] (R-HSA-417017)	0.556	3
UniProt:Q9UGI0 ZRANB1	1	ZRANB1 [cytosol] (R-HSA-6781939)	0.556	3
UniProt:Q9Y6K9 IKBKG	12	IKBKG D406V [cytosol] (R-HSA-5262943) IKBKG L153R [cytosol] (R-HSA-5262879) IKBKG E391* [cytosol] (R-HSA-5262924) IKBKG C417R [cytosol] (R-HSA-5262858) IKBKG R173G [cytosol] (R-HSA-5262966) IKBKG R175P [cytosol] (R-HSA-5262916) IKBKG 420Wext447 [cytosol] (R-HSA-5262978) monoSUMO1-K277,K309-IKBKG [nucleoplasm] (R-HSA-4755449) IKBKG [nucleoplasm] (R-HSA-4755413) K63polyUb-IKBKG [cytosol] (R-HSA-202530) Ub-285-IKBKG [cytosol] (R-HSA-741397) IKBKG [cytosol] (R-HSA-168108)	0.556	3
UniProt:Q9Y2T1 AXIN2	4	AXIN2 [cytosol] (R-HSA-3640821) RibC-AXIN2 [cytosol] (R-HSA-3640842) Ub-RibC-AXIN2 [cytosol] (R-HSA-3640859) ub-AXIN2 [cytosol] (R-HSA-4641131)	0.556	3
UniProt:Q8N720 ZNF655	1	ZNF655 [nucleoplasm] (R-HSA-2127575)	0.556	3
UniProt:Q96M91 CFA53			0.556	3
UniProt:Q13422-7 IKZF1			0.556	3
UniProt:Q2TAC2 CCD57			0.556	3
UniProt:Q9BRK4 LZTS2			0.556	3

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