Reactome | CWF19L2 [nucleoplasm]

CWF19L2 [nucleoplasm]

Stable Identifier

R-HSA-9770846

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

CWF19-like protein 2, C19L2_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q96BR9 ZBT8A

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External Reference Information

External Reference

UniProt:Q2TBE0 CWF19L2

Gene Names

CWF19L2

Chain

chain:1-894

Reference Genes

BioGPS Gene:143884 CWF19L2

COSMIC (genes):CWF19L2 CWF19L2

CTD Gene:143884 CWF19L2

dbSNP Gene:143884 CWF19L2

ENSEMBL:ENSG00000152404 CWF19L2

HGNC:26508 CWF19L2

KEGG:hsa:143884 CWF19L2

Monarch:143884 CWF19L2

NCBI Gene:143884 CWF19L2

UCSC:Q2TBE0 CWF19L2

Reference Transcript

RefSeq:NM_152434.2 CWF19L2

Other Identifiers

11724822_a_at

11724823_s_at

11752229_a_at

143884

16743994

228916_PM_at

228916_at

237040_PM_at

237040_at

3389786

3389787

3389788

3389789

3389790

3389791

3389792

3389793

3389796

3389797

3389798

3389799

3389800

3389804

3389805

3389806

3389807

3389808

3389810

3389811

3389813

3389821

3389823

3389831

3389833

3389834

3389837

3389838

3389839

3389840

3389842

3389844

3389846

64155_at

7951447

81897_at

A_23_P161719

GE79905

GO:0000398

GO:0005515

GO:0005654

GO:0016071

GO:0071014

HMNXSV003031036

Hs.160699.0.A1_3p_at

Hs.24380.0.A1_3p_at

ILMN_1668498

PH_hs_0002146

TC11002259.hg

Participates

as an output of

Disassembly of the Intron Lariat Spliceosome (new) (Homo sapiens)

as a component of

Intron Lariat Spliceosome (ILS) [nucleoplasm] (Homo sapiens)

as an input of

Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) (Homo sapiens)

Inferred To

cwf19 [nucleoplasm] (Schizosaccharomyces pombe)

CWF19L2 [nucleoplasm] (Bos taurus)

CWF19L2 [nucleoplasm] (Caenorhabditis elegans)

CWF19L2 [nucleoplasm] (Canis familiaris)

CWF19L2 [nucleoplasm] (Dictyostelium discoideum)

CWF19L2 [nucleoplasm] (Drosophila melanogaster)

CWF19L2 [nucleoplasm] (Gallus gallus)

CWF19L2 [nucleoplasm] (Plasmodium falciparum)

CWF19L2 [nucleoplasm] (Sus scrofa)

Cwf19l2 [nucleoplasm] (Mus musculus)

Cwf19l2 [nucleoplasm] (Rattus norvegicus)

cwf19l2 [nucleoplasm] (Danio rerio)

cwf19l2 [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

NP_689647.2

OpenTargets

ENSG00000152404

ENSEMBL

ENST00000282251, ENSP00000282251

HPA

ENSG00000152404-CWF19L2

PRO

Q2TBE0

Pharos - Targets

Q2TBE0

PDB

6ID1, 6ID0

Interactors (94)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q15742 NAB2	1	NAB2 [nucleoplasm] (R-HSA-9612177)	0.718	6
UniProt:P14136 GFAP	3	p-GFAP [lysosomal membrane] (R-HSA-9626054) GFAP [lysosomal membrane] (R-HSA-9625195) GFAP [cytosol] (R-HSA-1253311)	0.718	6
UniProt:P14373 TRIM27	2	TRIM27 [cytosol] (R-HSA-8851002) TRIM27 [nucleoplasm] (R-HSA-2997690)	0.718	6
UniProt:Q9Y6D9 MAD1L1	1	MAD1L1 [cytosol] (R-HSA-141433)	0.718	6
UniProt:Q15427 SF3B4	1	SF3B4 [nucleoplasm] (R-HSA-71975)	0.718	6
UniProt:P50221 MEOX1			0.718	6
UniProt:Q9BYV2 TRI54			0.718	6
UniProt:Q6NUQ1 RINT1	1	RINT1 [cytosol] (R-HSA-6810991)	0.718	6
UniProt:Q9P1Z2 CACO1			0.718	6
UniProt:O94972 TRIM37	1	TRIM37 [cytosol] (R-HSA-976049)	0.718	6
UniProt:Q9C026 TRIM9	1	TRIM9 [cytosol] (R-HSA-976054)	0.718	6
UniProt:Q13573 SNW1	1	SNW1 [nucleoplasm] (R-HSA-351663)	0.666	5
UniProt:Q8IYI6 EXOC8	2	EXOC8 [plasma membrane] (R-HSA-264948) EXOC8 [cytosol] (R-HSA-5623388)	0.556	3
UniProt:Q9Y250 LZTS1			0.556	3
UniProt:Q9NQ69 LHX9	1	LHX9 [nucleoplasm] (R-HSA-9011158)	0.556	3
UniProt:P51114-2 FXR1			0.556	3
UniProt:Q8NHQ1 CEP70	1	CEP70 [cytosol] (R-HSA-380257)	0.556	3
UniProt:Q5T7B8-2 KIF24			0.556	3
UniProt:Q9H0C1 ZMY12			0.556	3
UniProt:Q96MT8-3 CEP63			0.556	3
UniProt:Q9BYV9 BACH2			0.556	3
UniProt:Q8TC57 M1AP			0.556	3
UniProt:Q8N137 CNTRB			0.556	3
UniProt:P17661 DES	1	DES [cytosol] (R-HSA-390570)	0.556	3
UniProt:Q9H257-2 CARD9			0.556	3
UniProt:Q9UBR4-2 LHX3			0.556	3
UniProt:Q9GZM8 NDEL1	1	NDEL1 [cytosol] (R-HSA-376258)	0.556	3
UniProt:Q13137 CACO2			0.556	3
UniProt:Q4G0R1 Q4G0R1			0.556	3
UniProt:P08670 VIM	11	Vimentin [lysosomal lumen] (R-HSA-9659977) Vimentin [cytosol] (R-HSA-9646687) Vimentin [microtubule organizing center] (R-HSA-9657898) Vimentin [late endosome lumen] (R-HSA-9660019) VIM [cytosol] (R-HSA-201600) VIM(2-259) [cytosol] (R-HSA-350323) VIM(260-466) [cytosol] (R-HSA-350314) VIM(2-429) [cytosol] (R-HSA-350317) VIM(430-466) [cytosol] (R-HSA-350316) VIM(86-466) [cytosol] (R-HSA-350294) VIM(2-85) [cytosol] (R-HSA-350264)	0.556	3
UniProt:Q5JR59-3 MTUS2			0.556	3
UniProt:P13682 ZNF35			0.556	3
UniProt:Q9NRI5-2 DISC1			0.556	3
UniProt:Q8IZU0 FAM9B			0.556	3
UniProt:Q68D86 C102B			0.556	3
UniProt:A0A0C3SFZ9 A0A0C3SFZ9			0.556	3
UniProt:O43586 PSTPIP1	1	PSTPIP1 [cytosol] (R-HSA-879220)	0.556	3
UniProt:Q96BR9 ZBT8A			0.556	3
UniProt:Q96ED9-2 HOOK2			0.556	3
UniProt:Q9NSC5 HOMER3	1	HOMER3 [cytosol] (R-HSA-6794236)	0.556	3
UniProt:Q4V328 GRAP1			0.556	3
UniProt:O75031 HSF2B			0.556	3
UniProt:Q96ED9 HOOK2			0.556	3
UniProt:Q69YN2 C19L1			0.556	3
UniProt:O75558 STX11			0.556	3
UniProt:Q9Y6K9 IKBKG	12	IKBKG [cytosol] (R-HSA-168108) Ub-285-IKBKG [cytosol] (R-HSA-741397) K63polyUb-IKBKG [cytosol] (R-HSA-202530) IKBKG [nucleoplasm] (R-HSA-4755413) monoSUMO1-K277,K309-IKBKG [nucleoplasm] (R-HSA-4755449) IKBKG 420Wext447 [cytosol] (R-HSA-5262978) IKBKG R175P [cytosol] (R-HSA-5262916) IKBKG R173G [cytosol] (R-HSA-5262966) IKBKG C417R [cytosol] (R-HSA-5262858) IKBKG E391* [cytosol] (R-HSA-5262924) IKBKG L153R [cytosol] (R-HSA-5262879) IKBKG D406V [cytosol] (R-HSA-5262943)	0.556	3
UniProt:A6NC98 CC88B			0.556	3
UniProt:Q86TI0 TBC1D1	2	TBC1D1 [cytoplasmic vesicle membrane] (R-HSA-1454718) p-S237-TBC1D1 [cytosol] (R-HSA-1454673)	0.556	3
UniProt:Q9BWT7 CAR10			0.556	3
UniProt:Q8TAP6 CEP76	1	CEP76 [cytosol] (R-HSA-380281)	0.556	3
UniProt:Q9UBB4 ATX10			0.556	3
UniProt:Q8N1B4 VPS52	1	VPS52 [trans-Golgi network membrane] (R-HSA-6811029)	0.556	3
UniProt:A1L4K1 FSD2			0.556	3
UniProt:Q12933 TRAF2	5	TRAF2 [cytosol] (R-HSA-66370) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) TRAF2 [nucleoplasm] (R-HSA-8862199)	0.556	3
UniProt:Q9H257 CARD9	3	CARD9 [cytosol] (R-HSA-561194) p-T231-CARD9 [plasma membrane] (R-HSA-5607623) CARD9 [plasma membrane] (R-HSA-5607662)	0.556	3
UniProt:Q9UBB9 TFIP11	1	TFIP11 [nucleoplasm] (R-HSA-8869310)	0.556	3
UniProt:Q9Y2T1 AXIN2	4	AXIN2 [cytosol] (R-HSA-3640821) ub-AXIN2 [cytosol] (R-HSA-4641131) RibC-AXIN2 [cytosol] (R-HSA-3640842) Ub-RibC-AXIN2 [cytosol] (R-HSA-3640859)	0.556	3
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.556	3
UniProt:Q9NRD5 PICK1	2	PICK1 [plasma membrane] (R-HSA-416989) PICK1 [endocytic vesicle membrane] (R-HSA-417017)	0.556	3
UniProt:O95995 GAS8	1	GAS8 [cytosol] (R-HSA-5633057)	0.556	3
UniProt:Q9UGI0 ZRANB1	1	ZRANB1 [cytosol] (R-HSA-6781939)	0.556	3
UniProt:Q8N720 ZNF655	1	ZNF655 [nucleoplasm] (R-HSA-2127575)	0.556	3
UniProt:Q96M91 CFA53			0.556	3
UniProt:Q13422-7 IKZF1			0.556	3
UniProt:Q2TAC2 CCD57			0.556	3
UniProt:Q9BRK4 LZTS2			0.556	3
UniProt:P48059-3 LIMS1			0.556	3
UniProt:Q86VP1 TAX1BP1	1	TAX1BP1 [cytosol] (R-HSA-937346)	0.556	3
UniProt:Q5VU43-2 PDE4DIP			0.556	3
UniProt:Q9BVG8-5 KIFC3			0.556	3
UniProt:Q6A162 KRT40	1	KRT40 [cytosol] (R-HSA-6809605)	0.556	3
UniProt:A6NEM1 GG6L9			0.556	3
UniProt:P51116 FXR2			0.556	3
UniProt:Q5JR59 MTUS2			0.556	3
UniProt:Q9UJC3 HOOK1			0.556	3
UniProt:P36406 TRI23			0.556	3
UniProt:Q63ZY3 KANK2			0.556	3
UniProt:Q96JN2-2 CCDC136			0.556	3
UniProt:Q8N6L0 KASH5			0.556	3
UniProt:Q8WXH2 JPH3			0.556	3
UniProt:O94929-2 ABLIM3			0.556	3
UniProt:Q13625-3 TP53BP2			0.556	3
UniProt:Q9HCI5 MAGE1			0.527	2
UniProt:Q9BQ65 USB1			0.527	2
UniProt:Q08830 FGL1			0.527	2
UniProt:P62306 SNRPF	2	SNRPF [cytosol] (R-HSA-191852) SNRPF [nucleoplasm] (R-HSA-71907)	0.527	2
UniProt:Q9UMS4 PRPF19	1	PRPF19 [nucleoplasm] (R-HSA-5420907)	0.527	3
UniProt:Q9BRX9 WDR83	1	WDR83 [endosome membrane] (R-HSA-5672942)	0.527	3
UniProt:P63162 SNRPN	1	Me2-R108,R112-SNRPN [nucleoplasm] (R-HSA-8865931)	0.527	2
UniProt:Q9Y3R4 NEU2	1	NEU2 [cytosol] (R-HSA-1605759)	0.527	2
UniProt:O95926 SYF2	1	SYF2 [nucleoplasm] (R-HSA-8867884)	0.527	2
UniProt:P09661 SNRPA1	1	SNRPA1 [nucleoplasm] (R-HSA-71958)	0.527	4
UniProt:P62304 SNRPE	2	SNRPE [cytosol] (R-HSA-191782) SNRPE [nucleoplasm] (R-HSA-71905)	0.527	4
UniProt:P07910 HNRNPC	3	HNRNPC [nucleoplasm] (R-HSA-71933) SUMO1-K250-HNRNPC [nucleoplasm] (R-HSA-4570543) HNRNPC [cytosol] (R-HSA-9715136)	0.483	2

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