PSPH:Mg2+ dimer dephosphorylates O-P-Ser

Stable Identifier
R-HSA-977324
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
Synonyms
phosphoserine is dephosphorylated
ReviewStatus
5/5
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PSPH:Mg2+ dimer dephosphorylates O-P-Ser
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Dephosphorylation of O-phospho-L-serine to L-serine proceeds through a phospho-enzyme intermediate of the catalysing phosphatase PSP (Collet et al. 1997).
Literature References
PubMed ID Title Journal Year
9188776 Human L-3-phosphoserine phosphatase: sequence, expression and evidence for a phosphoenzyme intermediate

Rider, MH, Collet, JF, Gerin, I, Veiga-da-Cunha, M, Van Schaftingen, E

FEBS Lett 1997
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Catalyst Activity

L-phosphoserine phosphatase activity of PSPH:Mg2+ dimer [cytosol]

Physical Entity
PSPH:Mg2+ dimer [cytosol] (Homo sapiens)
Activity
L-phosphoserine phosphatase activity (GO:0036424)
Orthologous Events
PSPH:Mg2+ dimer dephosphorylates O-P-Ser (Bos taurus)
PSPH:Mg2+ dimer dephosphorylates O-P-Ser (Caenorhabditis elegans)
PSPH:Mg2+ dimer dephosphorylates O-P-Ser (Canis familiaris)
PSPH:Mg2+ dimer dephosphorylates O-P-Ser (Danio rerio)
PSPH:Mg2+ dimer dephosphorylates O-P-Ser (Dictyostelium discoideum)
PSPH:Mg2+ dimer dephosphorylates O-P-Ser (Drosophila melanogaster)
PSPH:Mg2+ dimer dephosphorylates O-P-Ser (Gallus gallus)
PSPH:Mg2+ dimer dephosphorylates O-P-Ser (Mus musculus)
PSPH:Mg2+ dimer dephosphorylates O-P-Ser (Rattus norvegicus)
PSPH:Mg2+ dimer dephosphorylates O-P-Ser (Saccharomyces cerevisiae)
PSPH:Mg2+ dimer dephosphorylates O-P-Ser (Schizosaccharomyces pombe)
PSPH:Mg2+ dimer dephosphorylates O-P-Ser (Sus scrofa)
PSPH:Mg2+ dimer dephosphorylates O-P-Ser (Xenopus tropicalis)
Cross References
Rhea
Authored
Stephan, R  (2010-10-16)
Reviewed
D'Eustachio, P  (2011-10-26)
Created
Jassal, B  (2010-10-18)
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