Reactome | PXLP-K200-PSAT1 [cytosol]

PXLP-K200-PSAT1 [cytosol]

Stable Identifier

R-HSA-977330

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9Y617 PSAT1

Gene Names

PSAT1, PSA

Chain

chain:1-370

Reference Genes

BioGPS Gene:29968 PSAT1

COSMIC (genes):PSAT1 PSAT1

CTD Gene:29968 PSAT1

dbSNP Gene:29968 PSAT1

ENSEMBL:ENSG00000135069 PSAT1

HGNC:19129 PSAT1

KEGG:hsa:29968 PSAT1

Monarch:29968 PSAT1

NCBI Gene:29968 PSAT1

OMIM:610936 PSAT1

UCSC:Q9Y617 PSAT1

Reference Transcript

Other Identifiers

11741479_a_at

11742991_a_at

11742992_s_at

11742993_x_at

11747348_a_at

11747349_s_at

11751230_a_at

11756182_s_at

17086193

220892_PM_s_at

220892_s_at

223062_PM_s_at

223062_s_at

2419487

2419489

2419494

2651075

2651076

2704010

29968

3134672

3175973

3175974

3175978

3175979

3175980

3175981

3175982

3175983

3175985

3175988

3175989

3175990

3175991

51016_s_at

78762_at

8156043

A_23_P259692

GE82594

GO:0003824

GO:0004648

GO:0005515

GO:0005737

GO:0005829

GO:0006520

GO:0006563

GO:0006564

GO:0006766

GO:0008483

GO:0008615

GO:0016740

GO:0030170

GO:0042802

GO:0043226

GO:0070062

HMNXSV003033891

ILMN_1692938

ILMN_1712563

PH_hs_0014797

TC09000358.hg

g10863954_3p_a_at

g13436073_3p_a_at

Participates

as a component of

PXLP-K200-PSAT1 dimer [cytosol] (Homo sapiens)

Inferred To

psat1 [cytosol] (Danio rerio)

psat1 [cytosol] (Xenopus tropicalis)

PXLP-K200-PSAT1 [cytosol] (Caenorhabditis elegans)

PXLP-K200-PSAT1 [cytosol] (Dictyostelium discoideum)

PXLP-K200-PSAT1 [cytosol] (Drosophila melanogaster)

PXLP-K200-PSAT1 [cytosol] (Gallus gallus)

PXLP-K200-PSAT1 [cytosol] (Mus musculus)

PXLP-K200-PSAT1 [cytosol] (Saccharomyces cerevisiae)

PXLP-K200-PSAT1 [cytosol] (Schizosaccharomyces pombe)

Psat1 [cytosol] (Rattus norvegicus)

PSAT1 [cytosol] (Bos taurus)

PSAT1 [cytosol] (Canis familiaris)

PSAT1 [cytosol] (Sus scrofa)

Modified Residues

Name

N6-pyridoxal phosphate-L-lysine at 200

Coordinate

200

PsiMod Name

N6-pyridoxal phosphate-L-lysine [MOD:00128]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6-pyridoxal phosphate-L-lysine.

Cross References

ENSEMBL

ENSP00000317606, ENSP00000365773, ENST00000347159, ENST00000376588

OpenTargets

ENSG00000135069

IntEnz

2.6.1.52

HPA

ENSG00000135069-PSAT1

PRO

Q9Y617

Pharos - Targets

Q9Y617

GlyGen

Q9Y617

Orphanet

PSAT1

HMDB Protein

HMDBP00851

PDB

3E77, 8A5V, 8A5W

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P12830 CDH1	8	CDH1(155-882) [plasma membrane] (R-HSA-198003) CDH1(751-882) [plasma membrane] (R-HSA-202929) CDH1(155-750) [plasma membrane] (R-HSA-202940) p-Y753,Y754-CDH1(155-882) [plasma membrane] (R-HSA-8876938) Ub-K,p-Y753,Y754-CDH1(155-882) [plasma membrane] (R-HSA-8877002) CDH1(701-882) [extracellular region] (R-HSA-2534158) CDH1(155-700) [plasma membrane] (R-HSA-2534244) CDH1(732-882) [plasma membrane] (R-HSA-3827997)	0.556	3
UniProt:P36957 DLST	5	Lipo-K110-DLST [mitochondrial matrix] (R-HSA-69993) SuccinyllipoH2-K110-DLST [mitochondrial matrix] (R-HSA-9853502) LipoH2-K110-DLST [mitochondrial matrix] (R-HSA-9853485) DLST [mitochondrial matrix] (R-HSA-6792574) GlutaryllipoH2-K110-DLST [mitochondrial matrix] (R-HSA-9858581)	0.556	3
UniProt:P27797 CALR	6	CALR [lumenal side of endoplasmic reticulum membrane] (R-HSA-985502) CALR [endoplasmic reticulum lumen] (R-HSA-195905) CALR [extracellular region] (R-HSA-2197641) CALR [endocytic vesicle lumen] (R-HSA-2239448) CALR [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-8863866) CALR [phagocytic vesicle membrane] (R-HSA-1236879)	0.556	3
UniProt:P0DTC3 3a	9	O-glycosyl 3a [virion membrane] (R-COV-9694395) O-glycosyl 3a [endocytic vesicle membrane] (R-COV-9694729) O-glycosyl 3a [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694386) GalNAc-O-3a [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9694658) 3a [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9694716) 3a [endoplasmic reticulum lumen] (R-COV-9694584) O-glycosyl 3a [endolysosome membrane] (R-COV-9754541) O-glycosyl 3a [plasma membrane] (R-COV-9694433) O-glycosyl 3a [extracellular region] (R-COV-9694387)	0.527	2

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