Reactome | CD46 [plasma membrane]

Stable Identifier

R-HSA-977362

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Membrane cofactor protein, MCP_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P15529 CD46

Gene Names

CD46, MCP, MIC10

Chain

signal peptide:1-34, chain:35-392

Reference Genes

COSMIC (genes):CD46 CD46

dbSNP Gene:4179 CD46

ENSEMBL:ENSG00000117335 CD46

Participates

as an input of

as a member of

as a component of

Inferred To

Cd46 [plasma membrane] (Mus musculus)

Cd46 [plasma membrane] (Rattus norvegicus)

LOC616002 [plasma membrane] (Bos taurus)

CD46 [plasma membrane] (Gallus gallus)

CD46 [plasma membrane] (Sus scrofa)

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
IntAct:EBI-12735745 C3B			0.761	4
UniProt:P78504 JAG1	2	Ub-JAG1 [plasma membrane] (R-HSA-9013079) JAG1 [plasma membrane] (R-HSA-157098)	0.632	5
UniProt:P01024 C3	20	C3d fragment [extracellular region] (R-HSA-198999) C3 alpha chain [azurophil granule lumen] (R-HSA-6799161) C3 beta chain [azurophil granule lumen] (R-HSA-6799159) C3 alpha chain [secretory granule lumen] (R-HSA-6800982) C3 beta chain [secretory granule lumen] (R-HSA-6801014) p-C3 [endoplasmic reticulum lumen] (R-HSA-8957056) C3 [endoplasmic reticulum lumen] (R-HSA-8956774) C3c alpha' chain fragment 1 precursor [extracellular region] (R-HSA-976816) C3c alpha' chain fragment 2 [extracellular region] (R-HSA-976818) C3c alpha' chain fragment 1 [extracellular region] (R-HSA-3266502) C3a-desArg [extracellular region] (R-HSA-8852808) C3dg [plasma membrane] (R-HSA-3266505) C3d [plasma membrane] (R-HSA-8853248) C3f [extracellular region] (R-HSA-976779) C3 beta chain [plasma membrane] (R-HSA-977593) C3c alpha' chain fragment 1 precursor [plasma membrane] (R-HSA-977595) C3c alpha' chain fragment 2 [plasma membrane] (R-HSA-977594) C3 alpha chain [extracellular region] (R-HSA-166820) C3b alpha' [extracellular region] (R-HSA-166830) C3 beta chain [extracellular region] (R-HSA-166821)	0.623	2
ChEBI:16851 1-PHOSPHATIDYL-1D-MYO-INOSITOL 3,5-BISPHOSPHATE			0.462	2

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