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SPATA2 [cytosol]
Stable Identifier
R-HSA-9796351
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Spermatogenesis-associated protein 2, KIAA0757, PD1
Locations in the PathwayBrowser for interactor UniProt:Q9Y2P0 ZN835
Expand all
Signal Transduction (Homo sapiens)
Death Receptor Signaling (Homo sapiens)
TNF signaling (Homo sapiens)
Regulation of TNFR1 signaling (Homo sapiens)
SPATA2 links CYLD to LUBAC (Homo sapiens)
SPATA2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UM82 SPATA2
Gene Names
SPATA2, KIAA0757, PD1
Chain
chain:1-520
Reference Genes
BioGPS Gene:9825 SPATA2
COSMIC (genes):SPATA2 SPATA2
CTD Gene:9825 SPATA2
dbSNP Gene:9825 SPATA2
ENSEMBL:ENSG00000158480 SPATA2
ENSEMBL_homo_sapiens_GENE:ENSG00000158480.11 SPATA2
HGNC:14681 SPATA2
KEGG Gene (Homo sapiens):9825 SPATA2
Monarch:9825 SPATA2
NCBI Gene:9825 SPATA2
OMIM:607662 SPATA2
UCSC:Q9UM82 SPATA2
Reference Transcript
RefSeq:NM_001135773.1 SPATA2
RefSeq:XM_011529116.1 SPATA2
RefSeq:NM_006038.3 SPATA2
RefSeq:XM_006723894.1 SPATA2
Other Identifiers
11725591_a_at
11725592_a_at
11725593_s_at
11725594_x_at
11727024_a_at
11751072_a_at
11758471_s_at
16920180
204433_PM_s_at
204433_s_at
204434_PM_at
204434_at
36050_at
3909036
3909037
3909038
3909039
3909040
3909041
3909042
3909043
3909044
3909046
3909047
8066953
9825
A_23_P210554
A_24_P164838
GE53466
GO:0001650
GO:0005515
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0005829
GO:0006954
GO:0007283
GO:0010803
GO:0012501
GO:0022414
GO:0023052
GO:0030159
GO:0036211
GO:0043226
GO:0044877
GO:0048856
GO:0050727
GO:0060090
GO:0060544
GO:0070266
GO:0070536
GO:0072520
GO:1990108
GO:1990381
HMNXSV003045891
ILMN_1681135
PH_hs_0028894
TC20000929.hg
g4730926_3p_a_at
g5174486_3p_at
Participates
as an input of
SPATA2 links CYLD to LUBAC (Homo sapiens)
as a component of
CYLD:SPATA2:LUBAC [cytosol] (Homo sapiens)
Inferred To
Spata2 [cytosol]
(Mus musculus)
Spata2 [cytosol]
(Rattus norvegicus)
SPATA2 [cytosol]
(Bos taurus)
SPATA2 [cytosol]
(Canis familiaris)
SPATA2 [cytosol]
(Gallus gallus)
SPATA2 [cytosol]
(Sus scrofa)
tamo [cytosol]
(Drosophila melanogaster)
spata2 [cytosol]
(Danio rerio)
spata2 [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
XP_011527418.1
,
NP_001129245.1
,
NP_006029.1
,
XP_006723957.1
OpenTargets
ENSG00000158480
HPA
ENSG00000158480-SPATA2
GeneCards
Q9UM82
Ensembl
ENST00000422556
,
ENSP00000416799
,
ENST00000289431
,
ENSG00000158480
,
ENSP00000289431
PRO
Q9UM82
Pharos - Targets
Q9UM82
PDB
5LJN
,
5LJM
Interactors (22)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.666
4
UniProt:P14373 TRIM27
2
TRIM27 [nucleoplasm]
(R-HSA-2997690)
TRIM27 [cytosol]
(R-HSA-8851002)
0.666
4
UniProt:Q9NQC7 CYLD
3
K48polyUb-K338, K530-CYLD [cytosol]
(R-HSA-9818664)
p-S418-CYLD [cytosol]
(R-HSA-5212667)
CYLD [cytosol]
(R-HSA-741420)
0.564
3
UniProt:Q9Y6D9 MAD1L1
1
MAD1L1 [cytosol]
(R-HSA-141433)
0.556
3
UniProt:Q9NU19 TB22B
0.556
3
UniProt:Q5JVL4 EFHC1
0.556
3
UniProt:O95872 GPAN1
0.556
3
UniProt:Q68D86 C102B
0.556
3
UniProt:P14136 GFAP
3
p-GFAP [lysosomal membrane]
(R-HSA-9626054)
GFAP [lysosomal membrane]
(R-HSA-9625195)
GFAP [cytosol]
(R-HSA-1253311)
0.556
3
UniProt:Q92993 KAT5
1
KAT5 [nucleoplasm]
(R-HSA-3321979)
0.556
3
UniProt:Q9UI12 ATP6V1H
2
ATP6V1H [cytosol]
(R-HSA-167578)
ATP6V1H [plasma membrane]
(R-HSA-167602)
0.556
3
UniProt:Q53TS8 CTSRT
0.556
3
UniProt:Q15025 TNIP1
1
TNIP1 [cytosol]
(R-HSA-5690853)
0.556
3
UniProt:Q96BZ8 LENG1
1
LENG1 [nucleoplasm]
(R-HSA-9769590)
0.556
3
UniProt:X5D778 X5D778
0.556
3
UniProt:Q9Y2P0 ZN835
0.556
3
UniProt:Q9BRK4 LZTS2
0.556
3
UniProt:Q9BVG8-5 KIFC3
0.556
3
UniProt:Q12933 TRAF2
5
TRAF2 [nucleoplasm]
(R-HSA-8862199)
K63polyUb-TRAF2 [nucleoplasm]
(R-HSA-8862194)
K63polyUb-TRAF2 [cytosol]
(R-HSA-8862193)
PolyUb-TRAF2 [cytosol]
(R-HSA-6782848)
TRAF2 [cytosol]
(R-HSA-66370)
0.553
2
UniProt:Q96PV0 SYNGAP1
1
SYNGAP1 [cytosol]
(R-HSA-5658217)
0.527
2
UniProt:O14936 CASK
1
CASK [cytosol]
(R-HSA-373631)
0.527
2
UniProt:Q14314 FGL2
2
FGL2 [extracellular region]
(R-HSA-6801586)
FGL2 [ficolin-1-rich granule lumen]
(R-HSA-6801499)
0.527
2
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