C4b binding protein binds C4bC2a

Stable Identifier
R-HSA-981648
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
C4 binding protein accelerates the decay of C4bC2a in a dose-dependent fashion, without causing degradation of C4b, and is presumed to bind to the convertase to mediate this effect.
Literature References
PubMed ID Title Journal Year
293746 Modulation of the classical pathway C3 convertase by plasma proteins C4 binding protein and C3b inactivator

Gigli, I, Fujita, T, Nussenzweig, V

Proc Natl Acad Sci U S A 1979
Participants
Participates
Authored
Reviewed
Created
Cite Us!