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NFE2L2 regulates pentose phosphate pathway genes
Stable Identifier
R-HSA-9818028
Type
Pathway
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
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KEAP1-NFE2L2 pathway (Homo sapiens)
Nuclear events mediated by NFE2L2 (Homo sapiens)
NFE2L2 regulates pentose phosphate pathway genes (Homo sapiens)
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Sub-pathway for representing the pentose phosphate pathway gene regulated by NFE2L2 (NRF2). NFE2L2 directs the transcription of genes related to the Pentose Phosphate pathway which helps in programming the metabolic pathway to cope with oxidative stress and also has a significant role in cancer progression (Chartoumpekis et al, 2015; DeBlasi et al, 2020)
Participants
Events
NFE2L2 binds the PGD gene
(Homo sapiens)
NFE2L2-dependent PGD gene expression
(Homo sapiens)
AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD
(Homo sapiens)
AcK-NFE2L2-dependent P6GD gene expression
(Homo sapiens)
NFE2L2 binds the TKT gene
(Homo sapiens)
NFE2L2-dependent TKT gene expression
(Homo sapiens)
NFE2L2 binds the TALDO1 gene
(Homo sapiens)
NFE2L2-dependent TALDO1 gene expression
(Homo sapiens)
Participates
as an event of
Nuclear events mediated by NFE2L2 (Homo sapiens)
Authored
Tiwari, K (2022-10-10)
Created
Tiwari, K (2022-10-10)
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