Reactome | WFDC2 [extracellular region]

WFDC2 [extracellular region]

Stable Identifier

R-HSA-9830363

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

WAP four-disulfide core domain protein 2, WFDC2_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q14508 WFDC2

Gene Names

WFDC2, HE4, WAP5

Chain

signal peptide:1-30, chain:31-124

Reference Genes

BioGPS Gene:10406 WFDC2

COSMIC (genes):WFDC2 WFDC2

CTD Gene:10406 WFDC2

dbSNP Gene:10406 WFDC2

ENSEMBL:ENSG00000101443 WFDC2

HGNC:15939 WFDC2

KEGG:hsa:10406 WFDC2

Monarch:10406 WFDC2

NCBI Gene:10406 WFDC2

OMIM:617548 WFDC2

UCSC:Q14508 WFDC2

Reference Transcript

RefSeq:NM_006103.3 WFDC2

Other Identifiers

10406

11717917_a_at

11744513_a_at

11753734_x_at

11759605_at

1552261_PM_at

1552261_at

1553089_PM_a_at

1553089_a_at

16914264

203892_PM_at

203892_at

33933_at

3886939

3886940

3886941

3886942

3886945

3886946

3886952

3886953

3886954

3886955

3886956

3886957

3886958

3886960

3886961

8063000

A_23_P218675

A_24_P14464

GE59885

GO:0002376

GO:0004866

GO:0004867

GO:0004869

GO:0005515

GO:0005576

GO:0005615

GO:0006508

GO:0007283

GO:0019731

GO:0019828

GO:0022414

GO:0030414

GO:0043226

GO:0045087

GO:0070062

GO:0098542

GO:0098772

HMNXSV003026845

Hs2.2719.2.A1_3p_at

Hs2.2719.5.A1_3p_a_at

Hs2.2719.5.A1_3p_s_at

ILMN_1685427

ILMN_1706612

ILMN_1799120

PH_hs_0000353

X63187_at

Participates

as an output of

Expression of WFDC2 in the nephric duct (Homo sapiens)

Cross References

ENSEMBL

ENSP00000361761, ENSP00000340215, ENSG00000101443, ENST00000342873, ENST00000339946, ENST00000372676, ENST00000217425, ENSP00000217425, ENSP00000342890

OpenTargets

ENSG00000101443

GeneCards

WFDC2

HPA

ENSG00000101443-WFDC2

PRO

Q14508

Pharos - Targets

Q14508

Interactors (17)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P07355 ANXA2	6	ANXA2 [azurophil granule lumen] (R-HSA-6798766) ANXA2 [extracellular region] (R-HSA-6806242) p-S26-ANXA2 [cytosol] (R-HSA-9865163) p-Y24,S26-ANXA2 [cytosol] (R-HSA-9865224) ANXA2 [cytosol] (R-HSA-5263667) ANXA2 [external side of plasma membrane] (R-HSA-5336164)	0.736	37
UniProt:Q9Y680 FKBP7			0.666	4
UniProt:A1A5C7-2 SLC22A23			0.556	3
UniProt:P11912 CD79A	2	p-Y188,Y199-CD79A [plasma membrane] (R-HSA-983539) CD79A [plasma membrane] (R-HSA-197154)	0.556	3
UniProt:Q3SXY8 ARL13B	8	PolyUb-Misfolded ARL13B [lysosomal lumen] (R-HSA-9660004) PolyUb-Misfolded ARL13B [cytosol] (R-HSA-9641129) Ub-Misfolded ARL13B [cytosol] (R-HSA-9641119) Misfolded ARL13B [cytosol] (R-HSA-9640110) Misfolded ARL13B [cilium] (R-HSA-9640116) ARL13B [cilium] (R-HSA-5618181) PolyUb-Misfolded ARL13B [late endosome lumen] (R-HSA-9659986) ARL13B [plasma membrane] (R-HSA-9716787)	0.556	3
UniProt:Q5T7V8 GORAB			0.556	3
UniProt:Q7Z7G2 CPLX4			0.556	3
UniProt:Q5JX71 F209A			0.556	3
UniProt:P27105 STOM	4	STOM [tertiary granule membrane] (R-HSA-6800960) STOM [plasma membrane] (R-HSA-6806258) STOM [specific granule membrane] (R-HSA-6799569) STOM [azurophil granule membrane] (R-HSA-6800997)	0.556	3
UniProt:P00387 CYB5R3	3	CYB5R3(27-301) [azurophil granule lumen] (R-HSA-6799217) CYB5R3(27-301) [extracellular region] (R-HSA-6806205) MyrG-CYB5R3(2-301) [mitochondrial outer membrane] (R-HSA-198771)	0.556	3
UniProt:O75208 COQ9	1	COQ9 [mitochondrial inner membrane] (R-HSA-8932994)	0.556	3
UniProt:Q96RD7 PANX1	1	PANX1 [plasma membrane] (R-HSA-375344)	0.556	3
UniProt:Q9Y320 TMX2			0.556	3
UniProt:Q96BA8 CREB3L1	7	CREB3L1 [Golgi membrane] (R-HSA-8874155) CREB3L1(427-519) [Golgi membrane] (R-HSA-8874139) CREB3L1(1-426) [Golgi membrane] (R-HSA-8874153) CREB3L1 [endoplasmic reticulum membrane] (R-HSA-8874157) CREB3L1(1-375) [cytosol] (R-HSA-8874215) CREB3L1(376-426) [Golgi membrane] (R-HSA-8874213) CREB3L1(1-375) [nucleoplasm] (R-HSA-8874222)	0.556	3
UniProt:Q562E7 WDR81	1	WDR81 [cytosol] (R-HSA-9714850)	0.527	2
UniProt:Q14554 PDIA5	1	PDIA5 [endoplasmic reticulum membrane] (R-HSA-535514)	0.527	2
UniProt:P08253 MMP2	5	MMP2(110-660) [extracellular region] (R-HSA-381456) MMP2(30-660) [extracellular region] (R-HSA-1604364) MMP2(30-66) [extracellular region] (R-HSA-1604347) MMP2(67-660) [extracellular region] (R-HSA-1604345) MMP2(67-109) [extracellular region] (R-HSA-1604371)	0.499	11

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