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LNPEP [cytosol]
Stable Identifier
R-HSA-983098
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
LAP, Leucyl-cystinyl aminopeptidase, LNPEP, LCAP_HUMAN, IRAP (Insulin regulated aminopeptidase)
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases (Homo sapiens)
IFN gamma stimulated aminopeptidases [cytosol] (Homo sapiens)
LNPEP [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UIQ6 LNPEP
Gene Names
LNPEP, OTASE
Chain
chain:1-1025, chain:155-1025
Reference Genes
COSMIC (genes):LNPEP LNPEP
dbSNP Gene:4012 LNPEP
ENSEMBL:ENSG00000113441 LNPEP
Participates
as a member of
IFN gamma stimulated aminopeptidases [cytosol] (Homo sapiens)
Other forms of this molecule
LNPEP [cytoplasmic vesicle membrane]
LNPEP [early endosome lumen]
Inferred To
Dmel\CG4467 [cytosol]
(Drosophila melanogaster)
Dmel\CG6071 [cytosol]
(Drosophila melanogaster)
LNPEP [cytosol]
(Bos taurus)
LNPEP [cytosol]
(Caenorhabditis elegans)
LNPEP [cytosol]
(Canis familiaris)
LNPEP [cytosol]
(Dictyostelium discoideum)
LNPEP [cytosol]
(Drosophila melanogaster)
LNPEP [cytosol]
(Gallus gallus)
LNPEP [cytosol]
(Mus musculus)
LNPEP [cytosol]
(Rattus norvegicus)
LNPEP [cytosol]
(Sus scrofa)
Homologues of LNPEP [cytosol]
(Caenorhabditis elegans)
Homologues of LNPEP [cytosol]
(Dictyostelium discoideum)
Homologues of LNPEP [cytosol]
(Drosophila melanogaster)
pepCG2111 [cytosol]
(Drosophila melanogaster)
Dmel\CG40470 [cytosol]
(Drosophila melanogaster)
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P27824 CANX
3
CANX [endoplasmic reticulum lumen]
(R-HSA-195906)
CANX [lumenal side of endoplasmic reticulum membrane]
(R-HSA-983091)
CANX [endoplasmic reticulum membrane]
(R-HSA-9932989)
0.643
3
UniProt:P80370 DLK1
1
DLK1 [plasma membrane]
(R-HSA-1604447)
0.527
2
UniProt:P17931 LGALS3
3
LGALS3 [secretory granule membrane]
(R-HSA-6803327)
LGALS3 [plasma membrane]
(R-HSA-879445)
LGALS3 [ficolin-1-rich granule membrane]
(R-HSA-6803307)
0.527
4
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