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PCBP2 [cytosol]
Stable Identifier
R-HSA-983457
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Poly, PCBP2_HUMAN
Locations in the PathwayBrowser for interactor UniProt:P84103 SRSF3
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-1 Infection (Homo sapiens)
SARS-CoV-1-host interactions (Homo sapiens)
SARS-CoV-1 activates/modulates innate immune responses (Homo sapiens)
SARS-CoV-1 9b binds MAVS and PCBP2 (Homo sapiens)
PCBP2 [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Homo sapiens)
Negative regulators of DDX58/IFIH1 signaling (Homo sapiens)
Interaction of PCBP2 with MAVS (Homo sapiens)
PCBP2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q15366 PCBP2
Gene Names
PCBP2
Chain
chain:1-365
Reference Genes
BioGPS Gene:5094 PCBP2
COSMIC (genes):PCBP2 PCBP2
CTD Gene:5094 PCBP2
dbSNP Gene:5094 PCBP2
ENSEMBL:ENSG00000197111 PCBP2
HGNC:8648 PCBP2
KEGG:hsa:5094 PCBP2
Monarch:5094 PCBP2
NCBI Gene:5094 PCBP2
OMIM:601210 PCBP2
UCSC:Q15366 PCBP2
Reference Transcript
RefSeq:NM_001128914.1 PCBP2
RefSeq:NM_005016.5 PCBP2
RefSeq:NM_001128913.1 PCBP2
RefSeq:NM_031989.4 PCBP2
RefSeq:NM_001128912.1 PCBP2
RefSeq:NM_001098620.2 PCBP2
RefSeq:NM_001128911.1 PCBP2
Other Identifiers
11728665_a_at
11728666_s_at
11728667_x_at
11729213_a_at
11753946_x_at
11754995_a_at
11763199_at
11763376_s_at
204031_PM_s_at
204031_s_at
213263_PM_s_at
213263_s_at
213264_PM_at
213264_at
213517_PM_at
213517_at
229467_PM_at
229467_at
3140984
3140985
3140989
3140990
3140991
3416037
3416038
3416039
3416040
3416041
3416042
3416043
3416044
3416045
3416048
3416049
3416050
3416051
3416052
3416053
3416054
3416055
3416056
3416058
3416062
3416064
3416065
3416066
3416067
3416068
3416070
3416071
3416073
3416074
3416075
3416076
3416077
3416080
3416081
3416082
3416083
3416084
35745_f_at
35746_r_at
40997_at
5094
55393_at
78178_at
78180_g_at
7955817
85121_at
A_14_P118448
A_23_P204052
A_24_P141688
A_33_P3298492
GE81464
GO:0002376
GO:0003676
GO:0003677
GO:0003697
GO:0003723
GO:0003729
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005925
GO:0006325
GO:0006355
GO:0006357
GO:0010468
GO:0014069
GO:0016020
GO:0016071
GO:0019899
GO:0030163
GO:0031625
GO:0039694
GO:0043161
GO:0043226
GO:0045087
GO:0050687
GO:0051252
GO:0051607
GO:0060090
GO:0070062
GO:0075522
GO:0098542
GO:0106222
GO:0140585
GO:0140588
GO:0160049
GO:1990904
HMNXSV003000464
HMNXSV003049278
Hs.211601.1.S1_3p_at
Hs.63525.2.A1_3p_at
Hs.88650.0.A1_3p_at
ILMN_1724825
ILMN_2312296
PH_hs_0029183
TC12003242.hg
X78136_at
g4826885_3p_a_at
p3688
Participates
as a component of
9b:K48polyUb-MAVS:PCBP2:ITCH [mitochondrial outer membrane] (Homo sapiens)
9b:PCBP2:MAVS [mitochondrial outer membrane] (Homo sapiens)
viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:PCBP2:ITCH [mitochondrial outer membrane] (Homo sapiens)
viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:PCBP2 [mitochondrial outer membrane] (Homo sapiens)
as an input of
SARS-CoV-1 9b binds MAVS and PCBP2 (Homo sapiens)
Interaction of PCBP2 with MAVS (Homo sapiens)
Other forms of this molecule
PCBP2 [nucleoplasm]
Cross References
RefSeq
NP_001122385.1
,
NP_001122383.1
,
NP_005007.2
,
NP_114366.1
,
NP_001122386.1
,
NP_001122384.1
,
NP_001092090.1
OpenTargets
ENSG00000197111
ENSEMBL
ENSP00000449070
,
ENST00000546463
,
ENST00000552296
,
ENST00000437231
,
ENST00000359462
,
ENSP00000352228
,
ENSP00000352438
,
ENST00000439930
,
ENSP00000408949
,
ENSP00000448927
,
ENSP00000388008
,
ENST00000359282
,
ENST00000455667
,
ENST00000552819
,
ENST00000447282
,
ENST00000548933
,
ENSP00000449062
,
ENSP00000390304
,
ENSP00000394116
,
ENSP00000448762
HPA
ENSG00000197111-PCBP2
PRO
Q15366
Pharos - Targets
Q15366
GlyGen
Q15366
PDB
2JZX
,
2PQU
,
2P2R
,
2AXY
,
2PY9
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P13569 CFTR
17
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR [endosome membrane]
(R-HSA-6782965)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [lysosomal membrane]
(R-HSA-5627279)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
0.615
18
UniProt:P84103 SRSF3
1
SRSF3 [nucleoplasm]
(R-HSA-72035)
0.581
3
UniProt:P09012 SNRPA
1
SNRPA [nucleoplasm]
(R-HSA-71915)
0.556
3
UniProt:P11940 PABPC1
1
PABPC1 [cytosol]
(R-HSA-156803)
0.527
2
UniProt:Q12771 Q12771
0.527
2
UniProt:Q15365 PCBP1
1
PCBP1 [nucleoplasm]
(R-HSA-71919)
0.508
2
IntAct:EBI-2643306 CEBPA-UORF
0.499
4
UniProt:Q8IUH3 RBM45
0.462
2
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