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ILF2 [cytosol]
Stable Identifier
R-HSA-9836392
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
NF45
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Interferon Signaling (Homo sapiens)
Antiviral mechanism by IFN-stimulated genes (Homo sapiens)
PKR-mediated signaling (Homo sapiens)
p-PKR dimer phosphorylates ILF3:ILF2 (Homo sapiens)
ILF2 [cytosol] (Homo sapiens)
ILF2:ILF3 [cytosol] (Homo sapiens)
ILF2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q12905 ILF2
Gene Names
ILF2, NF45, PRO3063
Chain
chain:1-390
Reference Genes
BioGPS Gene:3608 ILF2
COSMIC (genes):ILF2 ILF2
CTD Gene:3608 ILF2
dbSNP Gene:3608 ILF2
ENSEMBL:ENSG00000143621 ILF2
ENSEMBL:ENSG00000143621.17 ILF2
HGNC:6037 ILF2
KEGG Gene (Homo sapiens):3608 ILF2
Monarch:3608 ILF2
NCBI Gene:3608 ILF2
OMIM:603181 ILF2
UCSC:Q12905 ILF2
Reference Transcript
RefSeq:NM_001267809.1 ILF2
RefSeq:NM_004515.3 ILF2
Other Identifiers
11715401_s_at
11715402_x_at
16693515
18670651
18670652
18670653
18670654
18670656
18670657
18670658
18670659
18670660
18670663
18670664
18670665
18670666
18670667
200052_PM_s_at
200052_s_at
2436133
2436134
2436135
2436136
2436137
2436139
2436141
2436143
2436145
2436147
2436149
2436152
2436155
2436156
2436157
2436159
2436160
2436162
2627951
2627955
3561279
3608
36189_at
7892622
7893258
7893419
7893441
7893458
7893684
7893763
7894186
7895294
7895559
7895610
7896044
7920317
A_23_P257956
GE58912
GO:0003677
GO:0003723
GO:0003725
GO:0005515
GO:0005576
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0006351
GO:0006355
GO:0016020
GO:0031410
GO:0035580
GO:0043226
GO:0045893
GO:1904724
GO:1904813
GO:1990904
HMNXSV003013454
ILMN_1745172
PH_hs_0004277
TC01003273.hg
U10323_at
g4758601_3p_a_at
Participates
as an output of
p-PKR dimer phosphorylates ILF3:ILF2 (Homo sapiens)
as a component of
ILF2:ILF3 [cytosol] (Homo sapiens)
Other forms of this molecule
ILF2 [ficolin-1-rich granule lumen]
ILF2 [extracellular region]
ILF2 [specific granule lumen]
ILF2 [tertiary granule lumen]
Inferred To
O62349 [cytosol]
(Caenorhabditis elegans)
ilf2 [cytosol]
(Danio rerio)
ilf2 [cytosol]
(Xenopus tropicalis)
ILF2 [cytosol]
(Bos taurus)
A0A1D5NT76 [cytosol]
(Gallus gallus)
A0A5G2RJR2 [cytosol]
(Sus scrofa)
E2R9T6 [cytosol]
(Canis familiaris)
Ilf2 [cytosol]
(Mus musculus)
Ilf2 [cytosol]
(Rattus norvegicus)
Q9VG73 [cytosol]
(Drosophila melanogaster)
Cross References
RefSeq
NP_001254738.1
,
NP_004506.2
OpenTargets
ENSG00000143621
HPA
ENSG00000143621-ILF2
GeneCards
Q12905
Ensembl
ENSP00000355011
,
ENST00000361891
,
ENSG00000143621
PRO
Q12905
Pharos - Targets
Q12905
Interactors (21)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q12906 ILF3
3
p-T188,T315-ILF3 [cytosol]
(R-HSA-9836381)
ILF3 [cytosol]
(R-HSA-450564)
ILF3 [nucleoplasm]
(R-HSA-9760401)
0.69
6
UniProt:P67809 YBX1
5
p-S32,S36-YBX1 [nucleoplasm]
(R-HSA-9733227)
p-S32,S36-YBX1 [cytosol]
(R-HSA-9736837)
YBX1 [cytosol]
(R-HSA-9736840)
YBX1 [nucleoplasm]
(R-HSA-72041)
YBX1 [extracellular region]
(R-HSA-9017791)
0.662
6
UniProt:Q08752 PPID
1
PPID [nucleoplasm]
(R-HSA-8939168)
0.591
4
UniProt:Q6FHY5 Q6FHY5
0.556
3
UniProt:Q9NRD5 PICK1
2
PICK1 [plasma membrane]
(R-HSA-416989)
PICK1 [endocytic vesicle membrane]
(R-HSA-417017)
0.556
3
UniProt:P46940 IQGAP1
3
IQGAP1 [cytosol]
(R-HSA-5626371)
IQGAP1 [secretory granule membrane]
(R-HSA-6804803)
IQGAP1 [plasma membrane]
(R-HSA-381681)
0.556
3
UniProt:P14373 TRIM27
2
TRIM27 [nucleoplasm]
(R-HSA-2997690)
TRIM27 [cytosol]
(R-HSA-8851002)
0.556
3
IntAct:EBI-22311199 CCSB ORF ID
0.556
3
UniProt:Q9H0C1 ZMY12
0.556
3
UniProt:Q0VD86 INCA1
0.556
3
UniProt:P16104 H2AX
7
K63PolyUb-K14,K16,p-S140-H2AFX [nucleoplasm]
(R-HSA-5682847)
p-S140-H2AFX [nucleoplasm]
(R-HSA-75170)
p-S140,Y143-H2AFX [nucleoplasm]
(R-HSA-5683953)
p-Y143-H2AFX [nucleoplasm]
(R-HSA-5683942)
H2AFX [nucleoplasm]
(R-HSA-56151)
H2AFX [extracellular region]
(R-HSA-977583)
Me2sR4-H2AFX [nucleoplasm]
(R-HSA-5218317)
0.527
2
UniProt:Q6PKG0 LARP1
1
LARP1 [cytosol]
(R-HSA-9760421)
0.527
3
UniProt:P19320 VCAM1
1
VCAM1 [plasma membrane]
(R-HSA-197834)
0.527
4
UniProt:P0DTC9 N
13
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane]
(R-COV-9729325)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus]
(R-COV-9729339)
N [plasma membrane]
(R-COV-9694356)
SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol]
(R-COV-9756489)
N [cytosol]
(R-COV-9694300)
p-S188,206-N [cytosol]
(R-COV-9729324)
p-8S-N [cytosol]
(R-COV-9729335)
p-8S,2T-N [cytosol]
(R-COV-9729277)
p-11S,2T-N [cytosol]
(R-COV-9729264)
p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729308)
ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729275)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9729341)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729340)
0.527
3
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.483
4
UniProt:Q8IUH3 RBM45
0.462
2
UniProt:P35637 FUS
1
FUS [nucleoplasm]
(R-HSA-72040)
0.462
7
UniProt:Q09472 EP300
5
monoSUMO1-K1020,1024-EP300 [nucleoplasm]
(R-HSA-3899306)
Foxo4-S-S-EP300 [nucleoplasm]
(R-HSA-9617720)
FOXO4-S-S-EP300 [nucleoplasm]
(R-HSA-9617691)
p-S,T-EP300 [nucleoplasm]
(R-HSA-8878072)
EP300 [nucleoplasm]
(R-HSA-381325)
0.462
2
UniProt:P03372 ESR1
8
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
monoSUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
ESR1 [nucleoplasm]
(R-HSA-446168)
ESR1 [cytosol]
(R-HSA-9020968)
0.462
2
UniProt:P33992 MCM5
1
MCM5 [nucleoplasm]
(R-HSA-68551)
0.462
4
UniProt:Q92878 RAD50
1
RAD50 [nucleoplasm]
(R-HSA-75160)
0.462
3
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