Reactome | FASTKD5 [mitochondrial matrix]

FASTKD5 [mitochondrial matrix]

Stable Identifier

R-HSA-9837206

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

FAST kinase domain-containing protein 5, mitochondrial, FAKD5_HUMAN

Locations in the PathwayBrowser for interactor UniProt:P49146 NPY2R

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External Reference Information

External Reference

UniProt:Q7L8L6 FASTKD5

Gene Names

FASTKD5, KIAA1792

Chain

transit peptide:1-27, chain:28-764

Reference Genes

BioGPS Gene:60493 FASTKD5

COSMIC (genes):FASTKD5 FASTKD5

CTD Gene:60493 FASTKD5

dbSNP Gene:60493 FASTKD5

ENSEMBL:ENSG00000215251 FASTKD5

ENSEMBL_homo_sapiens_GENE:ENSG00000215251.5 FASTKD5

HGNC:25790 FASTKD5

KEGG Gene (Homo sapiens):60493 FASTKD5

Monarch:60493 FASTKD5

NCBI Gene:60493 FASTKD5

UCSC:Q7L8L6 FASTKD5

Reference Transcript

RefSeq:NM_021826.4 FASTKD5

Other Identifiers

11719477_a_at

219016_PM_at

219016_at

3895258

3895259

3895260

3895261

3895262

3895263

3895264

3895265

3895271

56996_at

60493

8064581

A_23_P380724

GE86050

GO:0000963

GO:0003723

GO:0005515

GO:0005739

GO:0005759

GO:0006397

GO:0016071

GO:0019843

GO:0035770

GO:0042645

GO:0043226

GO:0044528

GO:0140053

HMNXSV003046754

ILMN_1733377

g11141902_3p_at

Participates

as a component of

FASTKD5:12S rRNA, mitochondrial mRNAs [mitochondrial matrix] (Homo sapiens)

as an input of

FASTKD5 binds 12S rRNA and mitochondrial mRNAs (Homo sapiens)

Inferred To

Dmel\CG13850 [mitochondrial matrix] (Drosophila melanogaster)

FASTKD5 [mitochondrial matrix] (Bos taurus)

FASTKD5 [mitochondrial matrix] (Canis familiaris)

FASTKD5 [mitochondrial matrix] (Plasmodium falciparum)

FASTKD5 [mitochondrial matrix] (Sus scrofa)

Fastkd5 [mitochondrial matrix] (Mus musculus)

Homologues of FASTKD5 [mitochondrial matrix] (Drosophila melanogaster)

Homologues of FASTKD5 [mitochondrial matrix] (Plasmodium falciparum)

Dmel\CG2124 [mitochondrial matrix] (Drosophila melanogaster)

fask-1 [mitochondrial matrix] (Caenorhabditis elegans)

Cross References

RefSeq

NP_068598.1

OpenTargets

ENSG00000215251

HPA

ENSG00000215251-FASTKD5

GeneCards

Q7L8L6

Ensembl

ENST00000687419, ENST00000692371, ENSP00000510038, ENST00000380266, ENSG00000215251, ENSP00000510078, ENSP00000369618, ENSP00000510780, ENST00000688674

PRO

Q7L8L6

Pharos - Targets

Q7L8L6

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P31152 MAPK4	4	MAPK4 [nucleoplasm] (R-HSA-5686975) MAPK4 [cytosol] (R-HSA-5686973) p-S186 MAPK4 [cytosol] (R-HSA-5687023) p-S186 MAPK4 [nucleoplasm] (R-HSA-5687022)	0.643	4
UniProt:Q9UJV3-2 MID2			0.556	3
UniProt:P14373 TRIM27	2	TRIM27 [nucleoplasm] (R-HSA-2997690) TRIM27 [cytosol] (R-HSA-8851002)	0.556	3
UniProt:O95259 KCNH1	1	KCNH1 [plasma membrane] (R-HSA-2291883)	0.556	3
UniProt:P61086 UBE2K	2	UBE2K [cytosol] (R-HSA-934631) Ub-C92-UBE2K [cytosol] (R-HSA-8864200)	0.556	3
UniProt:P49146 NPY2R	1	NPY2R [plasma membrane] (R-HSA-388905)	0.527	2
UniProt:P0DTC5 M	10	M [plasma membrane] (R-COV-9755780) N-glycan M [virion membrane] (R-COV-9694385) M [virion membrane] (R-COV-9694320) M [endocytic vesicle membrane] (R-COV-9694563) N-glycan M [endocytic vesicle membrane] (R-COV-9694738) M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694439) N-glycan M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694446) M [endoplasmic reticulum membrane] (R-COV-9767620) nascent M [endoplasmic reticulum lumen] (R-COV-9694279) N-glycan M [endoplasmic reticulum membrane] (R-COV-9694684)	0.527	2

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