TGFBR3 regulates TGF-beta signaling

Stable Identifier
R-HSA-9839389
Type
Pathway
Species
Homo sapiens
ReviewStatus
3/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
TGFBR3 regulates TGF-beta signaling
Click the image above or here to open this pathway in the Pathway Browser
This subpathway describes the activation of TGFBR3 by TGF ligands and the subsequent regulation of TGF signaling by TGFBR3 (López‑Casillas et al.,1991,López‑Casillas et al.,1994, Blobe et al.,2001)
Literature References
PubMed ID Title Journal Year
8391934 Betaglycan presents ligand to the TGF beta signaling receptor

López-Casillas, F, Wrana, JL, Massagué, J

Cell 1993
8106553 Betaglycan can act as a dual modulator of TGF-beta access to signaling receptors: mapping of ligand binding and GAG attachment sites

López-Casillas, F, Payne, HM, Andres, JL, Massagué, J

J Cell Biol 1994
11323414 Functional roles for the cytoplasmic domain of the type III transforming growth factor beta receptor in regulating transforming growth factor beta signaling

Blobe, GC, Schiemann, WP, Pepin, MC, Beauchemin, M, Moustakas, A, Lodish, HF, O'Connor-McCourt, MD

J Biol Chem 2001
Participants
Events
Participates
as an event of
Orthologous Events
TGFBR3 regulates TGF-beta signaling (Bos taurus)
TGFBR3 regulates TGF-beta signaling (Canis familiaris)
TGFBR3 regulates TGF-beta signaling (Danio rerio)
TGFBR3 regulates TGF-beta signaling (Drosophila melanogaster)
TGFBR3 regulates TGF-beta signaling (Gallus gallus)
TGFBR3 regulates TGF-beta signaling (Mus musculus)
TGFBR3 regulates TGF-beta signaling (Rattus norvegicus)
TGFBR3 regulates TGF-beta signaling (Sus scrofa)
TGFBR3 regulates TGF-beta signaling (Xenopus tropicalis)
Cross References
BioModels Database
Authored
Tiwari, K  (2023-07-25)
Created
Tiwari, K  (2023-07-05)
Cite Us!