PSAP(405-486) [lysosomal lumen]

Stable Identifier
R-HSA-9840328
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lysosomal lumen
Synonyms
SAP D, Saposin-D
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
14630798 Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions

McRedmond, JP, Toomey, S, Fitzgerald, DJ, Cahill, DJ, Belton, O, Maguire, PB, Kislinger, T, Emili, A, Coppinger, JA, Cagney, G

Blood 2004
External Reference Information
External Reference
UniProt:P07602 PSAP
Gene Names
PSAP, GLBA, SAP1
Chain
signal peptide:1-16, chain:17-524, propeptide:17-59, chain:60-142, propeptide:143-194, chain:195-274, chain:195-273, propeptide:275-310, chain:311-390, propeptide:393-404, chain:405-486, propeptide:487-524
Reference Genes
BioGPS Gene:5660 PSAP
COSMIC (genes):PSAP PSAP
CTD Gene:5660 PSAP
dbSNP Gene:5660 PSAP
ENSEMBL:ENSG00000197746 PSAP
ENSEMBL_homo_sapiens_GENE:ENSG00000197746.15 PSAP
HGNC:9498 PSAP
KEGG Gene (Homo sapiens):5660 PSAP
Monarch:5660 PSAP
NCBI Gene:5660 PSAP
OMIM:176801 PSAP
UCSC:P07602 PSAP
Reference Transcript
Other Identifiers
11739069_s_at
11752509_s_at
11752510_x_at
11755296_a_at
16715241
200866_PM_s_at
200866_s_at
200871_PM_s_at
200871_s_at
3293761
3293763
3293764
3293765
3293766
3293767
3293768
3293769
3293770
3293774
3293775
3293777
3293779
3293780
3293781
3293782
3293787
3293788
3293789
3293790
3293793
3293794
3293795
3293800
3293801
36795_at
5660
7934196
A_23_P12680
A_24_P309317
GE81192
GO:0002020
GO:0005515
GO:0005543
GO:0005576
GO:0005615
GO:0005737
GO:0005764
GO:0005765
GO:0005768
GO:0005770
GO:0005773
GO:0005886
GO:0006629
GO:0006665
GO:0006914
GO:0007041
GO:0007193
GO:0008047
GO:0008289
GO:0010506
GO:0019216
GO:0022414
GO:0023052
GO:0030154
GO:0030312
GO:0031012
GO:0031410
GO:0035577
GO:0042802
GO:0042803
GO:0043202
GO:0043226
GO:0043231
GO:0048856
GO:0060736
GO:0060742
GO:0062023
GO:0070062
GO:0097110
GO:0098772
GO:1903771
GO:1905572
GO:1905573
GO:1905574
GO:1905575
GO:1905576
GO:1905577
HMNXSV003047545
ILMN_1749109
ILMN_2355559
J03077_s_at
PH_hs_0019280
TC10001374.hg
g11386146_3p_s_at
g337761_3p_a_at
Participates
as an output of
This entity regulates
Positively
Other forms of this molecule
PSAP(60-142) [extracellular region]
PSAP(17-524) [plasma membrane]
PSAP(17-524) [azurophil granule membrane]
PSAP(311-391) [lysosomal lumen]
PSAP(311-391) [lysosomal membrane]
PSAP(60-142) [lysosomal lumen]
PSAP [lysosomal lumen]
PSAP(195-273) [lysosomal lumen]
PSAP(?-?) [extracellular region]
PSAP(326-340) [extracellular region]
Inferred To
Homologues of PSAP(405-486) [lysosomal lumen] (Caenorhabditis elegans)
PSAP(405-486) [lysosomal lumen] (Gallus gallus)
Psap [lysosomal lumen] (Mus musculus)
Psap [lysosomal lumen] (Rattus norvegicus)
sapA [lysosomal lumen] (Dictyostelium discoideum)
Sap-r [lysosomal lumen] (Drosophila melanogaster)
spp-10 [lysosomal lumen] (Caenorhabditis elegans)
spp-8 [lysosomal lumen] (Caenorhabditis elegans)
PSAP [lysosomal lumen] (Bos taurus)
PSAP [lysosomal lumen] (Canis familiaris)
PSAP [lysosomal lumen] (Sus scrofa)
Cross References
RefSeq
OpenTargets
HPA
GeneCards
Ensembl
PRO
Pharos - Targets
Orphanet
HMDB Protein
PDB
Interactors (8)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P28799 GRN  2 0.702 6
 UniProt:O96006 ZBED1  1 0.666 4
 UniProt:P50542-3 PEX5      0.556 3
 UniProt:P48730-2 CSNK1D      0.556 3
 UniProt:Q92624 APBP2      0.556 3
 UniProt:P05067 APP  20 0.556 3
 UniProt:P07948 LYN  7 0.556 3
 UniProt:P31944 CASP14  2 0.471 3
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