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p-S473-AKT1 [cytosol]
Stable Identifier
R-HSA-9841264
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
RAC-alpha serine/threonine-protein kinase ecNumber evidence="30 78 79"2.7.11.1/ecNumber, AKT1_HUMAN, PKB
Icon
Locations in the PathwayBrowser for interactor UniProt:Q8IXJ9 ASXL1
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Mitochondrial unfolded protein response (UPRmt) (Homo sapiens)
Phosphorylation of AKT1 on serine-473 in response to reactive oxygen species (Homo sapiens)
p-S473-AKT1 [cytosol] (Homo sapiens)
p-S473-AKT1 phosphorylates ESR1 on serine-167 (Homo sapiens)
p-S473-AKT1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P31749 AKT1
Gene Names
AKT1, PKB, RAC
Chain
chain:1-480
Reference Genes
BioGPS Gene:207 AKT1
COSMIC (genes):AKT1 AKT1
CTD Gene:207 AKT1
dbSNP Gene:207 AKT1
ENSEMBL:ENSG00000142208 AKT1
ENSEMBL_homo_sapiens_GENE:ENSG00000142208.18 AKT1
HGNC:391 AKT1
KEGG Gene (Homo sapiens):207 AKT1
Monarch:207 AKT1
NCBI Gene:207 AKT1
OMIM:164730 AKT1
UCSC:P31749 AKT1
Reference Transcript
RefSeq:NM_001014431.1 AKT1
RefSeq:NM_005163.2 AKT1
RefSeq:XM_005267401.1 AKT1
RefSeq:NM_001014432.1 AKT1
Other Identifiers
11716087_s_at
11722186_a_at
11722187_a_at
1564_at
16797157
207
207163_PM_s_at
207163_s_at
3581133
3581134
3581135
3581136
3581137
3581138
3581143
3581144
3581145
3581148
3581150
3581152
3581155
3581157
3581159
3581161
3581169
3581174
3581175
3581176
3581177
3581178
3581179
3581180
7981494
A_23_P2960
A_33_P3275235
GE58023
GO:0000166
GO:0000278
GO:0001649
GO:0001893
GO:0001934
GO:0001938
GO:0002042
GO:0002376
GO:0003376
GO:0003824
GO:0004672
GO:0004674
GO:0004712
GO:0005515
GO:0005516
GO:0005524
GO:0005547
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0005815
GO:0005819
GO:0005829
GO:0005856
GO:0005886
GO:0005911
GO:0005929
GO:0005938
GO:0005975
GO:0005977
GO:0005978
GO:0005979
GO:0006006
GO:0006091
GO:0006351
GO:0006355
GO:0006399
GO:0006417
GO:0006468
GO:0006469
GO:0006606
GO:0006629
GO:0006809
GO:0006886
GO:0006913
GO:0006914
GO:0006915
GO:0006924
GO:0006954
GO:0006979
GO:0007005
GO:0007155
GO:0007165
GO:0007173
GO:0007186
GO:0007249
GO:0007281
GO:0007399
GO:0008283
GO:0008286
GO:0008289
GO:0008637
GO:0008643
GO:0009408
GO:0009725
GO:0010033
GO:0010467
GO:0010507
GO:0010595
GO:0010628
GO:0010629
GO:0010748
GO:0010761
GO:0010763
GO:0010765
GO:0010907
GO:0010951
GO:0010975
GO:0012501
GO:0015630
GO:0016020
GO:0016071
GO:0016242
GO:0016301
GO:0016310
GO:0016567
GO:0016740
GO:0018105
GO:0018107
GO:0019049
GO:0019221
GO:0019899
GO:0019901
GO:0022414
GO:0022605
GO:0023052
GO:0030027
GO:0030154
GO:0030163
GO:0030235
GO:0030291
GO:0030307
GO:0030334
GO:0031295
GO:0031397
GO:0031641
GO:0031663
GO:0031929
GO:0031982
GO:0031999
GO:0032079
GO:0032091
GO:0032094
GO:0032287
GO:0032436
GO:0032869
GO:0032880
GO:0032991
GO:0033138
GO:0034330
GO:0034405
GO:0034614
GO:0035556
GO:0035655
GO:0035924
GO:0036064
GO:0036211
GO:0036294
GO:0038061
GO:0042593
GO:0042802
GO:0042803
GO:0042981
GO:0043066
GO:0043154
GO:0043161
GO:0043226
GO:0043276
GO:0043325
GO:0043488
GO:0043491
GO:0043536
GO:0044782
GO:0045429
GO:0045600
GO:0045725
GO:0045737
GO:0045746
GO:0045861
GO:0045893
GO:0045944
GO:0046326
GO:0046622
GO:0046777
GO:0046889
GO:0048009
GO:0048266
GO:0048661
GO:0048856
GO:0048870
GO:0050877
GO:0051000
GO:0051091
GO:0051146
GO:0051247
GO:0055085
GO:0060079
GO:0060416
GO:0060644
GO:0060709
GO:0060716
GO:0061024
GO:0070141
GO:0070848
GO:0071276
GO:0071356
GO:0071363
GO:0071364
GO:0071380
GO:0071889
GO:0071901
GO:0072655
GO:0072656
GO:0072659
GO:0090201
GO:0097011
GO:0097194
GO:0098542
GO:0098772
GO:0098794
GO:0098978
GO:0099104
GO:0099175
GO:0106310
GO:0110002
GO:0140052
GO:0140096
GO:0150033
GO:0160049
GO:1900087
GO:1900182
GO:1901653
GO:1901796
GO:1902018
GO:1902176
GO:1903038
GO:1903078
GO:1903721
GO:1904263
GO:1905552
GO:1990090
GO:1990418
GO:2000010
GO:2000074
GO:2000402
GO:2001240
GO:2001243
HMNXSV003045285
ILMN_1748661
ILMN_2388507
ILMN_2410909
M63167_at
PH_hs_0024085
TC14001560.hg
g4885060_3p_a_at
Participates
as an output of
Phosphorylation of AKT1 on serine-473 in response to reactive oxygen species (Homo sapiens)
Other forms of this molecule
p-T308,S473-AKT1 E17K [nucleoplasm]
p-T308,S473-AKT1 E17K [cytosol]
AKT1 E17K [cytosol]
p-S473-AKT1 E17K [plasma membrane]
AKT1 E17K [plasma membrane]
p-T308,S473-AKT1 [plasma membrane]
p-Y315,Y326-AKT1 [cytosol]
p-T308-AKT1 [cytosol]
AKT1 [cytosol]
AKT1 [plasma membrane]
p-S473-AKT1 [plasma membrane]
p-T308,S473-AKT1 [cytosol]
p-T308,S473-AKT1 [nucleoplasm]
Inferred To
phospho-AKT1 [cytosol]
(Gallus gallus)
phospho-p-S473-AKT1 [cytosol]
(Caenorhabditis elegans)
phospho-p-S473-AKT1 [cytosol]
(Danio rerio)
phospho-p-S473-AKT1 [cytosol]
(Dictyostelium discoideum)
phospho-p-S473-AKT1 [cytosol]
(Drosophila melanogaster)
phospho-p-S473-AKT1 [cytosol]
(Mus musculus)
phospho-p-S473-AKT1 [cytosol]
(Rattus norvegicus)
phospho-p-S473-AKT1 [cytosol]
(Saccharomyces cerevisiae)
phospho-p-S473-AKT1 [cytosol]
(Schizosaccharomyces pombe)
Homologues of p-S473-AKT1 [cytosol]
(Caenorhabditis elegans)
Homologues of p-S473-AKT1 [cytosol]
(Dictyostelium discoideum)
Homologues of p-S473-AKT1 [cytosol]
(Saccharomyces cerevisiae)
Homologues of p-S473-AKT1 [cytosol]
(Schizosaccharomyces pombe)
Modified Residues
Name
O-phospho-L-serine at 473
Coordinate
473
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
XP_005267458.1
,
NP_005154.2
,
NP_001014432.1
,
NP_001014431.1
ZINC - World Drugs
AKT1_HUMAN
Guide to Pharmacology - Targets
1479
OpenTargets
ENSG00000142208
ZINC - FDA approved
AKT1_HUMAN
ZINC - Substances
AKT1_HUMAN
ZINC - Biogenic
AKT1_HUMAN
ZINC target
P31749
PRO
P31749
PDB
4EKK
,
7APJ
,
1UNQ
,
6HHF
,
1H10
,
1UNR
,
3O96
,
3MV5
,
1UNP
,
7MYX
,
6S9X
,
3CQW
,
6CCY
,
6S9W
,
6NPZ
,
3CQU
,
3OW4
,
3QKM
,
2UZS
,
3QKL
,
4EJN
,
2UZR
,
6HHJ
,
2UVM
,
3QKK
,
3MVH
,
6BUU
,
6HHI
,
7NH5
,
6HHH
,
7NH4
,
4GV1
,
6HHG
,
4EKL
,
3OCB
,
5KCV
ZINC - Investigational
AKT1_HUMAN
ZINC - Metabolites
AKT1_HUMAN
GeneCards
P31749
HPA
ENSG00000142208-AKT1
Ensembl
ENST00000554581
,
ENSP00000270202
,
ENST00000554848
,
ENSP00000497822
,
ENSG00000142208
,
ENST00000683722
,
ENST00000649815
,
ENST00000407796
,
ENSP00000384293
,
ENSP00000451828
,
ENST00000555528
,
ENSP00000507879
,
ENST00000402615
,
ENSP00000451166
,
ENSP00000385326
,
ENST00000349310
,
ENSP00000450688
Pharos - Targets
P31749
Orphanet
20544
ZINC - Predictions - Purchasable
AKT1_HUMAN
HMDB Protein
HMDBP01385
Interactors (74)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P56279 TCL1A
0.83
8
UniProt:Q00987 MDM2
11
PolyUb-MDM2 [nucleoplasm]
(R-HSA-6782472)
monoSUMO1-K182-MDM2 [nucleoplasm]
(R-HSA-3000408)
MDM2 [plasma membrane]
(R-HSA-416843)
MDM2 [endocytic vesicle membrane]
(R-HSA-416849)
p-5S,T-MDM2 [nucleoplasm]
(R-HSA-6804954)
PolyUb,p-S166,S188-MDM2 [nucleoplasm]
(R-HSA-6795669)
p-S166,S188,T218-MDM2 [nucleoplasm]
(R-HSA-6792862)
MDM2 [nucleoplasm]
(R-HSA-69486)
MDM2 [cytosol]
(R-HSA-198644)
p-S166,S188-MDM2 [cytosol]
(R-HSA-198638)
p-S166,S188-MDM2 [nucleoplasm]
(R-HSA-6793669)
0.807
6
UniProt:P49841 GSK3B
4
GSK3B del304-316 [cytosol]
(R-HSA-5339682)
GSK3B [nucleoplasm]
(R-HSA-2022823)
p-S9-GSK3B [cytosol]
(R-HSA-3149577)
GSK3B [cytosol]
(R-HSA-2997551)
0.779
4
UniProt:O15530 PDPK1
3
p-S241-PDPK1 [cytosol]
(R-HSA-9860799)
PDPK1 [cytosol]
(R-HSA-202210)
PDPK1 [plasma membrane]
(R-HSA-61459)
0.767
4
UniProt:P67775 PPP2CA
4
MeL-PPP2CA [nucleoplasm]
(R-HSA-8857791)
p-Y307-PPP2CA [cytosol]
(R-HSA-8857939)
PPP2CA [nucleoplasm]
(R-HSA-165978)
PPP2CA [cytosol]
(R-HSA-165971)
0.756
4
UniProt:Q5T1C6 THEM4
3
THEM4 [mitochondrial matrix]
(R-HSA-162408)
THEM4 [cytosol]
(R-HSA-6809345)
THEM4 [plasma membrane]
(R-HSA-199437)
0.734
4
UniProt:P42345 MTOR
2
MTOR [nucleoplasm]
(R-HSA-5083674)
MTOR [cytosol]
(R-HSA-165662)
0.731
4
ChEBI:16618 1-PHOSPHATIDYL-1D-MYO-INOSITOL 3,4,5-TRISPHOSPHATE
0.724
5
UniProt:Q16543 CDC37
1
CDC37 [cytosol]
(R-HSA-1221609)
0.708
5
UniProt:P08670 VIM
11
VIM(2-85) [cytosol]
(R-HSA-350264)
VIM(86-466) [cytosol]
(R-HSA-350294)
VIM(430-466) [cytosol]
(R-HSA-350316)
VIM(2-429) [cytosol]
(R-HSA-350317)
VIM(260-466) [cytosol]
(R-HSA-350314)
VIM(2-259) [cytosol]
(R-HSA-350323)
VIM [cytosol]
(R-HSA-201600)
Vimentin [late endosome lumen]
(R-HSA-9660019)
Vimentin [microtubule organizing center]
(R-HSA-9657898)
Vimentin [cytosol]
(R-HSA-9646687)
Vimentin [lysosomal lumen]
(R-HSA-9659977)
0.706
29
UniProt:O43524 FOXO3
11
p-S215 FOXO3 [nucleoplasm]
(R-HSA-5687010)
p-S215 FOXO3 [cytosol]
(R-HSA-5687014)
FOXO3 [cytosol]
(R-HSA-5687032)
p-S43,S173,S294,S325-FOXO3 [nucleoplasm]
(R-HSA-8870627)
p-S43,S173,S294,S325-FOXO3 [cytosol]
(R-HSA-8870560)
FOXO3(?-673) [mitochondrial matrix]
(R-HSA-9841824)
Ac-K271,K290-FOXO3(?-673) [mitochondrial matrix]
(R-HSA-9841849)
Ac-K242,K259,K271,K290,K569-FOXO3 [nucleoplasm]
(R-HSA-9620514)
p-T32,S253,S315-FOXO3 [cytosol]
(R-HSA-9614413)
p-T32,S253,S315-FOXO3 [nucleoplasm]
(R-HSA-199289)
FOXO3 [nucleoplasm]
(R-HSA-199305)
0.692
3
UniProt:O95999 BCL10
3
K48polyUb-BCL10 [cytosol]
(R-HSA-8939329)
BCL10 [cytosol]
(R-HSA-202447)
p-BCL10 [cytosol]
(R-HSA-202488)
0.69
5
UniProt:Q6GPH4 XAF1
1
XAF1 [cytosol]
(R-HSA-1015680)
0.666
4
UniProt:P31751 AKT2
7
p-T309,S474-AKT2 [plasma membrane]
(R-HSA-202056)
p-T309-AKT2 [cytosol]
(R-HSA-202066)
AKT2 [cytosol]
(R-HSA-49859)
AKT2 [plasma membrane]
(R-HSA-202053)
p-S474-AKT2 [plasma membrane]
(R-HSA-2317312)
p-T309,S474-AKT2 [cytosol]
(R-HSA-202062)
p-T309,S474-AKT2 [nucleoplasm]
(R-HSA-202087)
0.641
3
UniProt:P23443 RPS6KB1
2
RPS6KB1 [cytosol]
(R-HSA-165716)
p-T412-RPS6KB1 [cytosol]
(R-HSA-165714)
0.64
3
UniProt:P53804 TTC3
0.639
4
UniProt:Q86V81 ALYREF
2
ALYREF [nucleoplasm]
(R-HSA-156649)
ALYREF [cytosol]
(R-HSA-158482)
0.639
5
UniProt:Q15047 SETDB1
1
SETDB1 [nucleoplasm]
(R-HSA-417136)
0.639
9
UniProt:P46527 CDKN1B
8
p-S10 CDKN1B [cytosol]
(R-HSA-9632829)
p-S10 CDKN1B [nucleoplasm]
(R-HSA-9632832)
p-T157-CDKN1B [cytosol]
(R-HSA-198629)
CDKN1B [cytosol]
(R-HSA-198622)
p-Y88-CDKN1B [cytosol]
(R-HSA-8848438)
p-Y88-CDKN1B [nucleoplasm]
(R-HSA-8942808)
p-T187-CDKN1B [nucleoplasm]
(R-HSA-187525)
CDKN1B [nucleoplasm]
(R-HSA-182563)
0.63
3
UniProt:Q13043 STK4
4
STK4(1-487) [cytosol]
(R-HSA-201627)
p-T183-STK4(1-326) [cytosol]
(R-HSA-2028682)
p-T183-STK4(1-487) [cytosol]
(R-HSA-2028258)
STK4(327-487) [cytosol]
(R-HSA-2028668)
0.619
13
UniProt:P04150 NR3C1
3
SUMO1-K277,K293-NR3C1 [nucleoplasm]
(R-HSA-4341106)
NR3C1 [cytosol]
(R-HSA-5618118)
NR3C1 [nucleoplasm]
(R-HSA-879837)
0.611
5
UniProt:P26358 DNMT1
2
monoSUMO1-K-DNMT1 [nucleoplasm]
(R-HSA-4655353)
DNMT1 [nucleoplasm]
(R-HSA-212181)
0.611
6
UniProt:P31749 AKT1
14
p-T308,S473-AKT1 E17K [nucleoplasm]
(R-HSA-2399994)
p-T308,S473-AKT1 E17K [cytosol]
(R-HSA-2243935)
AKT1 E17K [cytosol]
(R-HSA-2219526)
p-S473-AKT1 E17K [plasma membrane]
(R-HSA-2243944)
AKT1 E17K [plasma membrane]
(R-HSA-1500573)
p-S473-AKT1 [cytosol]
(R-HSA-9841264)
p-T308,S473-AKT1 [plasma membrane]
(R-HSA-199430)
p-Y315,Y326-AKT1 [cytosol]
(R-HSA-8848757)
p-T308-AKT1 [cytosol]
(R-HSA-198634)
AKT1 [cytosol]
(R-HSA-58252)
AKT1 [plasma membrane]
(R-HSA-199416)
p-S473-AKT1 [plasma membrane]
(R-HSA-377265)
p-T308,S473-AKT1 [cytosol]
(R-HSA-198356)
p-T308,S473-AKT1 [nucleoplasm]
(R-HSA-198357)
0.609
3
UniProt:Q96EB6 SIRT1
1
SIRT1 [nucleoplasm]
(R-HSA-427531)
0.602
5
UniProt:P19174 PLCG1
6
p-Y-PLCG1 [cytosol]
(R-HSA-9029082)
p-4Y-PLCG1 [plasma membrane]
(R-HSA-167679)
PLCG1 [cytosol]
(R-HSA-202320)
PLCG1 [plasma membrane]
(R-HSA-167682)
p-Y771,Y783,Y1254-PLCG1 [cytosol]
(R-HSA-202357)
p-Y771,Y783-PLCG1 [plasma membrane]
(R-HSA-1169084)
0.602
9
UniProt:O60437 PPL
2
PPL [cytosol]
(R-HSA-6810850)
PPL [cornified envelope]
(R-HSA-8847709)
0.573
2
UniProt:P62136 PPP1CA
1
PPP1CA [cytosol]
(R-HSA-163525)
0.571
4
UniProt:Q12778 FOXO1
5
p-S218-FOXO1 [nucleoplasm]
(R-HSA-5692651)
Ac-K245,K248,K265-FOXO1 [nucleoplasm]
(R-HSA-9626942)
FOXO1 [nucleoplasm]
(R-HSA-199300)
p-T24,S256,S319-FOXO1 [nucleoplasm]
(R-HSA-199306)
p-T24,S256,S319-FOXO1 [cytosol]
(R-HSA-211158)
0.571
2
UniProt:P08238 HSP90AB1
6
HSP90AB1 [secretory granule lumen]
(R-HSA-6801477)
HSP90AB1 [extracellular region]
(R-HSA-6806463)
HSP90AB1 [ficolin-1-rich granule lumen]
(R-HSA-6801491)
HSP90AB1 [cytosol]
(R-HSA-419617)
HSP90AB1 [nucleoplasm]
(R-HSA-5082399)
HSP90AB1 [lysosomal lumen]
(R-HSA-9622846)
0.564
3
UniProt:Q5S007 LRRK2
1
LRRK2 [cytosol]
(R-HSA-5661173)
0.558
6
UniProt:Q99683 MAP3K5
1
MAP3K5 [cytosol]
(R-HSA-167709)
0.558
2
UniProt:Q9UNE7-1 STUB1
0.558
5
UniProt:P06241 FYN
6
p-S21,Y420-FYN [cytosol]
(R-HSA-5218745)
p-Y531-FYN [cytosol]
(R-HSA-391819)
MyrG2-PalmC3,6-FYN [plasma membrane]
(R-HSA-9606873)
p-Y420-FYN [cytosol]
(R-HSA-391821)
MyrG-p-Y420-FYN [plasma membrane]
(R-HSA-1810410)
FYN [cytosol]
(R-HSA-200917)
0.556
3
UniProt:Q96D03 DDT4L
0.556
3
UniProt:Q9H0C5 BTBD1
1
BTBD1 [cytosol]
(R-HSA-8851650)
0.556
3
UniProt:Q15438 CYTH1
2
CYTH1 [cytosol]
(R-HSA-8847826)
CYTH1 [Golgi membrane]
(R-HSA-8847825)
0.556
3
UniProt:Q8WUY3 PRUN2
0.556
3
UniProt:Q96LI6-3 Q96LI63
0.556
3
UniProt:Q6UY14-3 ADAMTSL4
0.556
3
UniProt:Q8TAP6 CEP76
1
CEP76 [cytosol]
(R-HSA-380281)
0.556
3
UniProt:P54253 ATX1
0.556
6
IntAct:EBI-25830852 RZPDO839G03145
0.556
3
UniProt:P17028 ZNF24
0.556
3
UniProt:Q9UQM7 CAMK2A
6
p-T286-CAMK2A [plasma membrane]
(R-HSA-432796)
p-T286-CAMK2A [nucleoplasm]
(R-HSA-444797)
p-T286-CAMK2A [endocytic vesicle membrane]
(R-HSA-416999)
p-T286,T305,T306-CAMK2A [cytosol]
(R-HSA-4332334)
CAMK2A [cytosol]
(R-HSA-4332329)
p-T286-CAMK2A [cytosol]
(R-HSA-445368)
0.556
3
UniProt:P10599 TXN
4
2xHC-TXN [nucleoplasm]
(R-HSA-9617733)
TXN [nucleoplasm]
(R-HSA-9617732)
2xHC-TXN [cytosol]
(R-HSA-73668)
TXN [cytosol]
(R-HSA-66000)
0.556
3
UniProt:Q14696 MESD
0.556
3
UniProt:P17612 PRKACA
4
PRKACA [mitochondrial matrix]
(R-HSA-9838291)
PRKACA [ciliary base]
(R-HSA-5610402)
PRKACA [nucleoplasm]
(R-HSA-111936)
PRKACA [cytosol]
(R-HSA-57844)
0.556
3
UniProt:P22466 GAL
1
GAL [extracellular region]
(R-HSA-389038)
0.556
3
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
3
UniProt:P00533 EGFR
20
p-6Y-EGFR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869138)
p-5Y-EGFRvIII [plasma membrane]
(R-HSA-1248649)
EGFRvIII [plasma membrane]
(R-HSA-1214162)
p-6Y-EGFR E746_A750del;T790M [plasma membrane]
(R-HSA-1182985)
p-6Y-EGFR L858R;T790M [plasma membrane]
(R-HSA-1182984)
p-6Y-EGFR A767_V769dup [plasma membrane]
(R-HSA-1996343)
p-6Y-EGFR N771_H773dup [plasma membrane]
(R-HSA-1996342)
p-6Y-EGFR K739_I744dup [plasma membrane]
(R-HSA-1996346)
p-6Y-EGFR D770_N771insNPG [plasma membrane]
(R-HSA-1996335)
p-6Y-EGFR E746_A750del [plasma membrane]
(R-HSA-1181214)
p-6Y-EGFR L858R [plasma membrane]
(R-HSA-1173211)
p-6Y-EGFR G719S [plasma membrane]
(R-HSA-1169417)
p-6Y-EGFR L747_P753delinsS [plasma membrane]
(R-HSA-1228038)
p-6Y-EGFR L747_A750delinsP [plasma membrane]
(R-HSA-1228044)
p-6Y-EGFR L747_T751del [plasma membrane]
(R-HSA-1228041)
p-6Y-EGFR L747_S752del [plasma membrane]
(R-HSA-1228040)
p-6Y-EGFR L747_T751delinsP [plasma membrane]
(R-HSA-1228042)
p-6Y-EGFR E746_T751delinsA [plasma membrane]
(R-HSA-1228037)
p-6Y-EGFR E746_S752delinsV [plasma membrane]
(R-HSA-1228039)
p-6Y-EGFR L861Q [plasma membrane]
(R-HSA-1177541)
0.553
2
UniProt:P05771 PRKCB
5
PRKCB [plasma membrane]
(R-HSA-156467)
PRKCB [cytosol]
(R-HSA-58198)
p-T500-PRKCB [cytosol]
(R-HSA-5218728)
p-T500,T642,S661-PRKCB [cytosol]
(R-HSA-5218706)
p-T500,T642,S661-PRKCB [nucleoplasm]
(R-HSA-5223294)
0.547
2
UniProt:P49327 FASN
3
FASN [cytosol]
(R-HSA-199233)
decanoyl-FASN [cytosol]
(R-HSA-5655935)
FASN [cytosol]
(R-HSA-54659)
0.547
2
UniProt:P30153 PPP2R1A
2
PPP2R1A [nucleoplasm]
(R-HSA-165968)
PPP2R1A [cytosol]
(R-HSA-165982)
0.544
2
UniProt:Q05513 PRKCZ
5
p-T410,T563-PRKCZ [cytosol]
(R-HSA-5218698)
PRKCZ [cytosol]
(R-HSA-58218)
PRKCZ [cell junction]
(R-HSA-2134483)
p-T410-PRKCZ [cytosol]
(R-HSA-437181)
pS, p-T410-PRKCZ [cytosol]
(R-HSA-9632824)
0.544
2
UniProt:Q9BZQ8 NIBA1
0.544
2
UniProt:Q92547 TOPBP1
1
TOPBP1 [nucleoplasm]
(R-HSA-5684878)
0.544
2
UniProt:Q14643 ITPR1
2
ITPR1 [platelet dense tubular network membrane]
(R-HSA-3325593)
ITPR1 [endoplasmic reticulum membrane]
(R-HSA-3006433)
0.536
2
UniProt:P04049 RAF1
20
p-S338,Y340,Y341-RAF1 [cytosol]
(R-HSA-5624465)
p-S338-RAF1 [cytosol]
(R-HSA-5624469)
p-S621-RAF1 S259F [cytosol]
(R-HSA-9656124)
p-S621-RAF1 S257L [cytosol]
(R-HSA-9656121)
p-S621-RAF1 P261L [cytosol]
(R-HSA-9656106)
p-S621-RAF1 N262K [cytosol]
(R-HSA-9656101)
p-S621-RAF1 P261A [cytosol]
(R-HSA-9656103)
p-S621-RAF1 P261S [cytosol]
(R-HSA-9656113)
p-S621-RAF1 S259T [cytosol]
(R-HSA-9656130)
p-S621-RAF1 P261T [cytosol]
(R-HSA-9656115)
p-S621-RAF1 P261R [cytosol]
(R-HSA-9656110)
p-S621-RAF1 S259P [cytosol]
(R-HSA-9656127)
p-S621-RAF1 T260I [cytosol]
(R-HSA-9656136)
p-S621-RAF1 T260R [cytosol]
(R-HSA-9656139)
p-S621-RAF1 V263A [cytosol]
(R-HSA-9656148)
p-S621-RAF1 R256S [cytosol]
(R-HSA-9656119)
p-S621-RAF1 T491I [cytosol]
(R-HSA-9656143)
p-S621-RAF1 D486N [cytosol]
(R-HSA-9656088)
p-S621-RAF1 S427G [cytosol]
(R-HSA-9656134)
p-S621-RAF1 L613V [cytosol]
(R-HSA-9656098)
0.536
2
UniProt:P24468 NR2F2
1
NR2F2 [nucleoplasm]
(R-HSA-1183002)
0.527
2
UniProt:P38646 HSPA9
6
HSPA9 [mitochondrial matrix]
(R-HSA-8878802)
HSPA9 [mitochondrial inner membrane]
(R-HSA-1252206)
HSPA9(1-679) [cytosol]
(R-HSA-1267964)
HSPA9(1-679) [mitochondrial intermembrane space]
(R-HSA-1267968)
HSPA9 [nucleoplasm]
(R-HSA-5252128)
HSPA9 [cytosol]
(R-HSA-5251993)
0.527
3
UniProt:P07900 HSP90AA1
8
HSP90AA1 [secretory granule lumen]
(R-HSA-6801515)
HSP90AA1 [ficolin-1-rich granule lumen]
(R-HSA-6801470)
HSP90AA1 [plasma membrane]
(R-HSA-534996)
HSP90AA1 [endocytic vesicle lumen]
(R-HSA-3221912)
HSP90AA1 [extracellular region]
(R-HSA-3221946)
HSP90AA1 [nucleoplasm]
(R-HSA-5082401)
HSP90AA1 [cytosol]
(R-HSA-192864)
HSP90AA1 [lysosomal lumen]
(R-HSA-9622850)
0.527
3
UniProt:Q96S96 PEBP4
0.524
2
UniProt:P29067
3
Arrb2 [endocytic vesicle membrane]
(R-RNO-9910881)
Arrb2 [cytosol]
(R-RNO-6783000)
Arrb2 [cytosol]
(R-RNO-416464)
0.524
2
UniProt:Q83730 MT5
0.524
3
UniProt:P20248 CCNA2
3
PolyUb-CCNA2 [nucleoplasm]
(R-HSA-6783099)
CCNA2 [cytosol]
(R-HSA-157444)
CCNA2 [nucleoplasm]
(R-HSA-68905)
0.524
2
UniProt:Q9UKG1 APPL1
1
APPL1 [endosome membrane]
(R-HSA-373630)
0.519
2
UniProt:Q9NYB0 TERF2IP
1
TERF2IP [nucleoplasm]
(R-HSA-174873)
0.508
2
UniProt:Q8IXJ9 ASXL1
1
ASXL1 [nucleoplasm]
(R-HSA-5689645)
0.508
2
IntAct:EBI-4399559 UBIQ
0.499
2
UniProt:Q92793 CREBBP
4
monoSUMO1-K998,K1033,K1056-CREBBP [nucleoplasm]
(R-HSA-3927877)
FOXO4-S-S-CREBBP [nucleoplasm]
(R-HSA-9617684)
CREBBP [cytosol]
(R-HSA-9756493)
CREBBP [nucleoplasm]
(R-HSA-193545)
0.499
3
UniProt:P10636 MAPT
3
MAPT(422-758) [cytosol]
(R-HSA-350642)
MAPT(2-421) [cytosol]
(R-HSA-350628)
MAPT [cytosol]
(R-HSA-201574)
0.499
2
UniProt:P04792 HSBP1
3
HSPB1 [cytosol]
(R-HSA-450563)
p-S15,S78,S82-HSP27 [cytosol]
(R-HSA-5218697)
p-S78,S82 HSPB1 [cytosol]
(R-HSA-5687009)
0.483
3
UniProt:P11021 HSPA5
6
HSPA5 [extracellular region]
(R-HSA-351322)
HSPA5 [endoplasmic reticulum lumen]
(R-HSA-387190)
HSPA5 [endoplasmic reticulum membrane]
(R-HSA-351315)
HSPA5 [cytosol]
(R-HSA-5252115)
HSPA5 [nucleoplasm]
(R-HSA-5252042)
HSPA5 [lumenal side of endoplasmic reticulum membrane]
(R-HSA-985498)
0.471
2
UniProt:P10276 RARA
3
SUMO2-K166,177,399-p-S219,269-RARA [nucleoplasm]
(R-HSA-5334830)
polySUMO2-K166,K171,K399-RARA [nucleoplasm]
(R-HSA-4341042)
RARA [nucleoplasm]
(R-HSA-446164)
0.463
2
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