CLIP1(1-1083)-p-6Y LTK(488-864) fusion [plasma membrane]

Stable Identifier
R-HSA-9842573
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
CAP-Gly domain-containing linker protein 1, CLIP1_HUMAN
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
34819663 The CLIP1-LTK fusion is an oncogenic driverĀ in non-small-cell lung cancer

Ikeda, T, Nakachi, I, Watanabe, K, Kodani, M, Hayashi, K, Sakakibara-Konishi, J, Shibata, Y, Nishino, K, Izumi, H, Okamoto, I, Kirita, K, Goto, K, Nosaki, K, Yoh, K, Niho, S, Ishii, G, Matsumoto, S, Kuyama, S, Sakai, T, Liu, J, Furuya, N, Sugiyama, E, Nakai, T, Tanaka, K, Kumagai, S, Yamasaki, A, Daga, H, Zenke, Y, Taima, K, Ebi, N, Hayashida, T, Kato, T, Fukuhara, T, Mori, S, Kobayashi, SS, Udagawa, H, Ohtsu, A, Nakamura, A

Nature 2021
External Reference Information
External Reference
Gene Names
CLIP1, CYLN1, RSN
Chain
chain:1-1438
Other Identifiers
11740471_s_at
11740472_a_at
11740473_a_at
11743785_x_at
1558924_PM_s_at
1558924_s_at
16771680
201975_PM_at
201975_at
210716_PM_s_at
210716_s_at
2527359
34350_at
3475588
3475589
3475590
3475591
3475595
3475596
3475597
3475603
3475611
3475614
3475616
3475622
3475623
3475624
3475625
3475627
3475628
3475631
3475632
3475635
3475638
3475641
3475642
3475644
3475649
3475650
3475653
3475656
3475658
3475659
3475673
6249
75192_at
76751_at
7967255
A_23_P25003
A_24_P306425
GE59911
GO:0000278
GO:0000776
GO:0001578
GO:0001726
GO:0005515
GO:0005634
GO:0005694
GO:0005737
GO:0005768
GO:0005813
GO:0005815
GO:0005829
GO:0005856
GO:0005874
GO:0005882
GO:0005938
GO:0007010
GO:0008017
GO:0008092
GO:0008270
GO:0015630
GO:0015631
GO:0016020
GO:0030659
GO:0031116
GO:0031122
GO:0031410
GO:0035371
GO:0042802
GO:0042995
GO:0043226
GO:0044354
GO:0046872
GO:0051010
GO:0065003
HMNXSV003039292
Hs2.432908.1.A1_3p_s_at
ILMN_1684038
ILMN_1723058
ILMN_2404085
PH_hs_0030090
TC12002073.hg
TC12003131.hg
X64838_at
g180621_3p_a_at
g4506750_3p_at
Participates
Other forms of this molecule
Modified Residues
Name
Insertion of residues 488 to 864 at 1084 from UniProt:P29376 LTK
Coordinate
1084
Name
O4'-phospho-L-tyrosine at 485
Coordinate
485
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 672
Coordinate
672
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 721
Coordinate
721
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 753
Coordinate
753
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 779
Coordinate
779
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 862
Coordinate
862
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Disease
Name Identifier Synonyms
non-small cell lung carcinoma DOID:3908 Non-small cell lung cancer (disorder), NSCLC, NSCLC
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Interactors (5)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q15691 MAPRE1  1 0.672 3
 UniProt:P68366 TUBA4A  9 0.618 3
 UniProt:Q04864-2 REL      0.556 3
 UniProt:P0DTC6 6  4 0.547 2
 UniProt:P13569 CFTR  17 0.483 4
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