Reactome | Chromokinesins form dimers

Chromokinesins form dimers

Stable Identifier

R-HSA-984671

Type

Reaction [transition]

Species

Homo sapiens

Compartment

cytosol

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Chromokinesins consist of the kinesin-4 and kinesin-10 families.They act in various steps of mitosis, including chromosome condensation, metaphase alignment, chromosome segregation and cytokinesis (Mazumdar & Misteli 2005). Both families consist of homodimeric microtubule-based plus-end directed motor proteins (Sekine et al. 1994, Yajima et al. 2003).

Literature References

PubMed ID	Title	Journal	Year
8599929	Kid, a novel kinesin-like DNA binding protein, is localized to chromosomes and the mitotic spindle Tsukita, S, Inoue, J, Toyoshima, Y, Yamamota, T, Fujimoto-Nishiyama, A, Yonemura, S, Tokai, N	EMBO J	1996
15326200	Human chromokinesin KIF4A functions in chromosome condensation and segregation Sundareshan, S, Mazumdar, M, Misteli, T	J Cell Biol	2004