Reactome | KIFAP3 [cytosol]

KIFAP3 [cytosol]

Stable Identifier

R-HSA-984736

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Kinesin-associated protein 3, KIFA3_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q6P6B1 ERIC5

Expand all

External Reference Information

External Reference

UniProt:Q92845 KIFAP3

Gene Names

KIFAP3, KIF3AP, SMAP

Chain

chain:1-792

Reference Genes

BioGPS Gene:22920 KIFAP3

COSMIC (genes):KIFAP3 KIFAP3

CTD Gene:22920 KIFAP3

dbSNP Gene:22920 KIFAP3

ENSEMBL:ENSG00000075945 KIFAP3

HGNC:17060 KIFAP3

Monarch:22920 KIFAP3

NCBI Gene:22920 KIFAP3

OMIM:601836 KIFAP3

UCSC:Q92845 KIFAP3

Reference Transcript

Other Identifiers

11739068_a_at

11746611_a_at

16696295

203333_PM_at

203333_at

22920

2443580

2443581

2443582

2443597

2443600

2443603

2443604

2443605

2443606

2443607

2443608

2443609

2443610

2443611

2443617

2443619

2443620

2443621

2443622

2443623

2443624

2443626

2443627

2443628

2443630

2443631

2443633

2443636

2443637

2443638

2443639

2443640

2443641

40779_at

7922268

A_23_P62920

GE61432

GO:0000228

GO:0000794

GO:0001750

GO:0001917

GO:0005515

GO:0005694

GO:0005783

GO:0005794

GO:0005813

GO:0005815

GO:0005829

GO:0005856

GO:0005871

GO:0005876

GO:0005929

GO:0005930

GO:0006915

GO:0007017

GO:0007018

GO:0007165

GO:0007405

GO:0007406

GO:0008092

GO:0008104

GO:0008283

GO:0010659

GO:0010667

GO:0012501

GO:0015630

GO:0016939

GO:0019894

GO:0019903

GO:0032391

GO:0035869

GO:0036064

GO:0043066

GO:0043226

GO:0044782

GO:0046587

GO:0065003

GO:0070242

GO:0070244

GO:0072383

GO:0097542

GO:0098794

GO:0098971

GO:0098978

GO:0120170

GO:1990075

HMNXSV003053237

ILMN_2119224

PH_hs_0025281

TC01003505.hg

U59919_at

g7657592_3p_at

Participates

as a component of

as an input of

Kinesin-2 is a heterotrimer (Homo sapiens)

Other forms of this molecule

KIFAP3 [cilium]

KIFAP3 [ciliary tip]

Inferred To

Kap3 [cytosol] (Drosophila melanogaster)

KIFAP3 [cytosol] (Canis familiaris)

KIFAP3 [cytosol] (Gallus gallus)

KIFAP3 [cytosol] (Sus scrofa)

Kifap3 [cytosol] (Mus musculus)

Kifap3 [cytosol] (Rattus norvegicus)

kap-1 [cytosol] (Caenorhabditis elegans)

Cross References

ENSEMBL

ENSP00000356739, ENSP00000444622, ENST00000367765, ENSP00000354560, ENST00000367767, ENST00000361580, ENSP00000356741, ENST00000538366

OpenTargets

ENSG00000075945

HPA

ENSG00000075945-KIFAP3

PRO

Q92845

Pharos - Targets

Q92845

GlyGen

Q92845

Interactors (25)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P19878 NCF2	2	NCF2 [cytosol] (R-HSA-1222600) p-T233-NCF2 [phagolysosome] (R-HSA-1996211)	0.926	14
UniProt:Q9Y496 KIF3A	3	KIF3A [cilium] (R-HSA-5610394) KIF3A [cytosol] (R-HSA-984767) KIF3A [ciliary tip] (R-HSA-5625377)	0.895	12
UniProt:O15066 KIF3B	3	KIF3B [ciliary tip] (R-HSA-5625378) KIF3B [cilium] (R-HSA-5624878) KIF3B [cytosol] (R-HSA-984662)	0.886	11
UniProt:P41227 NAA10			0.781	7
UniProt:P00540 MOS			0.556	3
UniProt:Q14D33 RTP5			0.556	3
UniProt:Q63ZY3 KANK2			0.556	3
UniProt:P09067 HXB5			0.556	3
UniProt:Q9H6X5-2 C19ORF44			0.556	3
UniProt:Q86VE0 MYPOP			0.556	3
UniProt:Q9BSU3 NAA11			0.556	3
UniProt:Q9NRI5 DISC1			0.553	2
UniProt:P62834 RAP1A	4	RAP1A [plasma membrane] (R-HSA-354118) RAP1A [endosome membrane] (R-HSA-190053) RAP1A [cytosol] (R-HSA-169884) RAP1A [specific granule membrane] (R-HSA-6806137)	0.527	2
UniProt:Q9BRG1 VPS25	1	VPS25 [cytosol] (R-HSA-917697)	0.527	2
UniProt:Q6P6B1 ERIC5			0.527	2
UniProt:O14782 KIF3C	3	KIF3C [ciliary tip] (R-HSA-5625380) KIF3C [cilium] (R-HSA-5624880) KIF3C [cytosol] (R-HSA-984660)	0.527	3
UniProt:Q99584 S10AD			0.527	2
UniProt:Q13177 PAK2	11	p-S141,T402-PAK2 [cytosol] (R-HSA-399824) PAK2 [cytosol] (R-HSA-211604) p-5S-PAK2 [cytosol] (R-HSA-211609) PAK2(213-524) [cytosol] (R-HSA-211653) p-5S-PAK2(2-212) [cytosol] (R-HSA-211588) p-T402-PAK2(213-524) [cytosol] (R-HSA-211654) p-T402-PAK2(213-524) [nucleoplasm] (R-HSA-211709) K48polyUb-p-T402-PAK-2p43 [cytosol] (R-HSA-3095873) p-Y130,S141,T402-PAK2 [cytosol] (R-HSA-5218705) PAK2(1-524) [plasma membrane] (R-HSA-164946) p-S141,T402-PAK2 [plasma membrane] (R-HSA-5096524)	0.527	2
UniProt:Q15836 VAMP3	6	VAMP3 [recycling endosome membrane] (R-HSA-2029063) VAMP3 [phagocytic vesicle membrane] (R-HSA-2029013) VAMP3 [plasma membrane] (R-HSA-8867599) VAMP3 [trans-Golgi network membrane] (R-HSA-6814624) VAMP3 [transport vesicle] (R-HSA-6814625) VAMP3 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869130)	0.527	2
UniProt:P17677 GAP43	2	GAP43 [plasma membrane] (R-HSA-452888) PALM-C3,4-GAP43 [plasma membrane] (R-HSA-8933482)	0.527	2
UniProt:Q9Y2R5 MRPS17	1	MRPS17 [mitochondrial inner membrane] (R-HSA-5368241)	0.508	2
UniProt:Q5SW79 CE170			0.508	2
UniProt:P82663 MRPS25	1	MRPS25 [mitochondrial inner membrane] (R-HSA-5368204)	0.508	2
UniProt:Q15599 NHRF2			0.508	2
UniProt:Q86VI3 IQGAP3	1	IQGAP3 [cytosol] (R-HSA-5625977)	0.508	2

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