Reactome | pancreatic ductal cell

pancreatic ductal cell

Stable Identifier

R-HSA-9853405

Type

Cell

Species

Homo sapiens

Synonyms

pancreatic ductal epithelial cell, PDEC

Locations in the PathwayBrowser

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Cytology

Organ

pancreas (UBERON:0001264)

Tissue

exocrine pancreas (UBERON:0000017)

Cell Type

pancreatic ductal cell (CL:0002079)

Markers

Protein

ANXA1 [cytosol] (Homo sapiens)

- Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche.Proc Natl Acad Sci U S A117,10876-10887(2020)Lanzoni, G., Domínguez-Bendala, J., Johnson, K., Qadir, MMF., Navarro-Rubio, B., Pastori, RL., García, MT., Ricordi, C., van Dijk, J., Griswold, A., Klein, D., Díaz, Á., Muñiz-Anquela, R., Moreno-Hernández, YB., Sant, D., Álvarez-Cubela, S., Sadiq, S.

HNF1B [nucleoplasm] (Homo sapiens)

- Heterogeneity of SOX9 and HNF1β in Pancreatic Ducts Is Dynamic.Stem Cell Reports10,725-738(2018)Guo, L., Rezanejad, H., Hollister-Lock, J., Li, WC., Deng, S., Keyzer, CA., Sullivan, BA., Bonner-Weir, S., Lei, J., Markmann, J., Ouziel-Yahalom, L.
- Discovery and 3D imaging of a novel ΔNp63-expressing basal cell type in human pancreatic ducts with implications in disease.Gut71,2030-42(2021)Esni, F., Fernandez Ruiz, A., Van Bulck, M., Real, FX., Madhloum, H., Waelput, W., Bouchart, C., Bouwens, L., D'Haene, N., Martens, S., Arsenijevic, T., Van Laethem, JL., De Paep, DL., Rooman, I., Heimberg, H., El Kaoutari, A., Casamitjana, J., Leuckx, G., Dusetti, N., Coolens, K., Lefesvre, P., Martinez de Villareal, J., in't Veld, P., Rovira, M., Jacquemin, P., Heremans, Y.

SOX9 [nucleoplasm] (Homo sapiens)

- Heterogeneity of SOX9 and HNF1β in Pancreatic Ducts Is Dynamic.Stem Cell Reports10,725-738(2018)Guo, L., Rezanejad, H., Hollister-Lock, J., Li, WC., Deng, S., Keyzer, CA., Sullivan, BA., Bonner-Weir, S., Lei, J., Markmann, J., Ouziel-Yahalom, L.
- Discovery and 3D imaging of a novel ΔNp63-expressing basal cell type in human pancreatic ducts with implications in disease.Gut71,2030-42(2021)Esni, F., Fernandez Ruiz, A., Van Bulck, M., Real, FX., Madhloum, H., Waelput, W., Bouchart, C., Bouwens, L., D'Haene, N., Martens, S., Arsenijevic, T., Van Laethem, JL., De Paep, DL., Rooman, I., Heimberg, H., El Kaoutari, A., Casamitjana, J., Leuckx, G., Dusetti, N., Coolens, K., Lefesvre, P., Martinez de Villareal, J., in't Veld, P., Rovira, M., Jacquemin, P., Heremans, Y.

KRT23 [cytosol] (Homo sapiens)

- Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche.Proc Natl Acad Sci U S A117,10876-10887(2020)Lanzoni, G., Domínguez-Bendala, J., Johnson, K., Qadir, MMF., Navarro-Rubio, B., Pastori, RL., García, MT., Ricordi, C., van Dijk, J., Griswold, A., Klein, D., Díaz, Á., Muñiz-Anquela, R., Moreno-Hernández, YB., Sant, D., Álvarez-Cubela, S., Sadiq, S.

ANXA3 [cytosol] (Homo sapiens)

- Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche.Proc Natl Acad Sci U S A117,10876-10887(2020)Lanzoni, G., Domínguez-Bendala, J., Johnson, K., Qadir, MMF., Navarro-Rubio, B., Pastori, RL., García, MT., Ricordi, C., van Dijk, J., Griswold, A., Klein, D., Díaz, Á., Muñiz-Anquela, R., Moreno-Hernández, YB., Sant, D., Álvarez-Cubela, S., Sadiq, S.

KRT19 [cytosol] (Homo sapiens)

- Stem cell marker prominin-1/AC133 is expressed in duct cells of the adult human pancreas.Pancreas36,e1-6(2008)Lardon, J., Huttner, WB., Bouwens, L., Ling, Z., Corbeil, D.
- In vitro cultivation of human fetal pancreatic ductal stem cells and their differentiation into insulin-producing cells.World J Gastroenterol10,1452-6(2004)Yao, ZX., Liu, JJ., Chen, XS., Qin, ML., Zhou, DS.
- Changes in the distribution of intermediate filament proteins and collagen IV in fetal and adult human pancreas. I. Localization of cytokeratin polypeptides.Histochemistry96,271-7(1991)Stosiek, P., Kasper, M., von Dorsche, H.
- Intermediate filaments as differentiation markers of exocrine pancreas. II. Expression of cytokeratins of complex and stratified epithelia in normal pancreas and in pancreas cancer.Int J Cancer54,720-7(1993)Vilá, MR., Ramaekers, FC., Corominas, JM., Real, FX., Skoudy, A.
- Intermediate filaments as differentiation markers of normal pancreas and pancreas cancer.Am J Pathol140,559-68(1992)Ramaekers, F., Real, FX., Skoudy, A., Schüssler, MH.

ERICH5 [plasma membrane] (Homo sapiens)

- The human pancreas proteome defined by transcriptomics and antibody-based profiling.PLoS One9,e115421(2014)Pontén, F., Hallström, BM., Schwenk, JM., Korsgren, O., Danielsson, A., Fagerberg, L., Uhlén, M., Lindskog, C.

TFPI2 [endoplasmic reticulum lumen] (Homo sapiens)

- Immunohistochemical localization of tissue factor pathway inhibitor-2 in human tumor tissue.Thromb Haemost90,140-6(2003)Kisiel, W., Kozlowski, L., Sierko, E., Wojtukiewicz, MZ., Zimnoch, L.

AQP1 [plasma membrane] (Homo sapiens)

- The Importance of Aquaporin 1 in Pancreatitis and Its Relation to the CFTR Cl^- Channel.Front Physiol9,854(2018)Rakonczay, Z., Balla, Z., Tóth, E., Pallagi, P., Zvara, Á., Puskás, LG., Borka, K., Balázs, A., Lerch, MM., Mayerle, J., Sendler, M., Kemény, LV., Gál, E., Becskeházi, E., Kühn, JP., Hegyi, P., Venglovecz, V.
- Distribution of aquaporin water channels AQP1 and AQP5 in the ductal system of the human pancreas.Gut52,1008-16(2003)Rácz, GZ., Varga, G., Steward, MC., Elkaer, ML., Burghardt, B., Kwon, TH., Nielsen, S.

CFTR [plasma membrane] (Homo sapiens)

- A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure.Cell Syst3,346-360.e4(2016)Gaujoux, R., Shen-Orr, SS., Klein, AM., Veres, A., Melton, DA., Wagner, BK., Baron, M., Yanai, I., Ryu, JH., Faust, AL., Vetere, A., Wolock, SL.
- Guanylin in the human pancreas: a novel luminocrine regulatory pathway of electrolyte secretion via cGMP and CFTR in the ductal system.Histochem Cell Biol115,131-45(2001)Hönscheid, M., Schmid, A., Kulaksiz, H., Eissele, R., Klempnauer, J., Cetin, Y.
- AnnoSpat annotates cell types and quantifies cellular arrangements from spatial proteomics.Nat Commun15,3744(2024)Kaestner, KH., Powers, AC., Wang, YJ., Brissova, M., Zhou, Y., Mongia, A., Zohora, FT., Burget, NG., Naji, A., Faryabi, RB., Schwartz, GW., Vahedi, G., Saunders, DC.
- The human pancreas proteome defined by transcriptomics and antibody-based profiling.PLoS One9,e115421(2014)Pontén, F., Hallström, BM., Schwenk, JM., Korsgren, O., Danielsson, A., Fagerberg, L., Uhlén, M., Lindskog, C.
- Patient-derived pancreas-on-a-chip to model cystic fibrosis-related disorders.Nat Commun10,3124(2019)Shik Mun, K., Naren, AP., Nathan, JD., Yang, F., Arora, K., Appakalai, BN., Ramananda, Y., Huang, Y., Palermo, JJ., Abu-El-Haija, M., Yarlagadda, S.
- Localization of the cystic fibrosis transmembrane conductance regulator in pancreas.J Clin Invest88,712-6(1991)Gorelick, FS., Cohn, JA., Marino, CR., Matovcik, LM.

SLC4A4 [plasma membrane] (Homo sapiens)

- Molecular cloning, chromosomal localization, tissue distribution, and functional expression of the human pancreatic sodium bicarbonate cotransporter.J Biol Chem273,17689-95(1998)Newman, D., Boorer, K., Pushkin, A., Hwang, J., Abuladze, N., Kurtz, I., Lee, I.
- The human pancreas proteome defined by transcriptomics and antibody-based profiling.PLoS One9,e115421(2014)Pontén, F., Hallström, BM., Schwenk, JM., Korsgren, O., Danielsson, A., Fagerberg, L., Uhlén, M., Lindskog, C.
- Localization of Na+-HCO-3 cotransporter (NBC-1) variants in rat and human pancreas.Am J Physiol Cell Physiol284,C729-37(2003)Moriyama, N., Tsukamoto, K., Kawakami, H., Horita, S., Fujita, T., Iso-O, N., Endou, H., Kunimi, M., Hara, C., Inatomi, J., Satoh, H., Kudo, A., Seki, G., Igarashi, T., Goto, A., Yamada, H.

CLDN10 [plasma membrane] (Homo sapiens)

- The human pancreas proteome defined by transcriptomics and antibody-based profiling.PLoS One9,e115421(2014)Pontén, F., Hallström, BM., Schwenk, JM., Korsgren, O., Danielsson, A., Fagerberg, L., Uhlén, M., Lindskog, C.

KRT7 [cytosol] (Homo sapiens)

- Changes in the distribution of intermediate filament proteins and collagen IV in fetal and adult human pancreas. I. Localization of cytokeratin polypeptides.Histochemistry96,271-7(1991)Stosiek, P., Kasper, M., von Dorsche, H.
- Tissue distribution of keratin 7 as monitored by a monoclonal antibody.Exp Cell Res170,235-49(1987)Huysmans, A., Schaart, G., Ramaekers, F., Moesker, O., Vooijs, P.
- Intermediate filaments as differentiation markers of exocrine pancreas. II. Expression of cytokeratins of complex and stratified epithelia in normal pancreas and in pancreas cancer.Int J Cancer54,720-7(1993)Vilá, MR., Ramaekers, FC., Corominas, JM., Real, FX., Skoudy, A.
- Intermediate filaments as differentiation markers of normal pancreas and pancreas cancer.Am J Pathol140,559-68(1992)Ramaekers, F., Real, FX., Skoudy, A., Schüssler, MH.

KRT17 [cytosol] (Homo sapiens)

- Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche.Proc Natl Acad Sci U S A117,10876-10887(2020)Lanzoni, G., Domínguez-Bendala, J., Johnson, K., Qadir, MMF., Navarro-Rubio, B., Pastori, RL., García, MT., Ricordi, C., van Dijk, J., Griswold, A., Klein, D., Díaz, Á., Muñiz-Anquela, R., Moreno-Hernández, YB., Sant, D., Álvarez-Cubela, S., Sadiq, S.
- Intermediate filaments as differentiation markers of exocrine pancreas. II. Expression of cytokeratins of complex and stratified epithelia in normal pancreas and in pancreas cancer.Int J Cancer54,720-7(1993)Vilá, MR., Ramaekers, FC., Corominas, JM., Real, FX., Skoudy, A.

CD74 [plasma membrane] (Homo sapiens)

- Effect of CD74 on the prognosis of patients with resectable pancreatic cancer.Hepatobiliary Pancreat Dis Int13,81-6(2014)Hua, R., Liu, DJ., Huo, YM., Sun, YW., Zhang, JF., Liu, W.

CA2 [cytosol] (Homo sapiens)

- Stem cell marker prominin-1/AC133 is expressed in duct cells of the adult human pancreas.Pancreas36,e1-6(2008)Lardon, J., Huttner, WB., Bouwens, L., Ling, Z., Corbeil, D.
- Immunohistochemical localization of carbonic anhydrase isoenzymes in the human pancreas.Gastroenterology80,796-9(1981)Kumpulainen, T., Jalovaara, P.

ANXA2 [cytosol] (Homo sapiens)

- Enhanced expression of annexin II in human pancreatic carcinoma cells and primary pancreatic cancers.Carcinogenesis14,2575-9(1993)Hollingsworth, MA., Kumble, KD., Vishwanatha, JK., Chiang, Y., Pour, PM.

PROM1 [plasma membrane] (Homo sapiens)

- Stem cell marker prominin-1/AC133 is expressed in duct cells of the adult human pancreas.Pancreas36,e1-6(2008)Lardon, J., Huttner, WB., Bouwens, L., Ling, Z., Corbeil, D.
- Expression of the "stem cell marker" CD133 in pancreas and pancreatic ductal adenocarcinomas.BMC Cancer8,48(2008)Sakariassen, PØ., Immervoll, H., Hoem, D., Molven, A., Steffensen, OJ.
- The stem cell marker CD133 (Prominin-1) is expressed in various human glandular epithelia.J Histochem Cytochem56,977-93(2008)Huttner, WB., Jászai, J., Mokry, J., Subrtová, D., Fonseca, AV., Ehrmann, J., Missol-Kolka, E., Hollerová, H., Arl, S., Kolár, Z., Karbanová, J., Janich, P., Lorra, C., Freund, D., Liebers, C., Corbeil, D.
- CD133 expression pattern distinguishes intraductal papillary mucinous neoplasms from ductal adenocarcinomas of the pancreas.Pancreas38,e207-14(2009)Ku, Y., Itoh, T., Hori, Y., Shimizu, K., Shimizu, M.
- Visualization of CD44 and CD133 in normal pancreas and pancreatic ductal adenocarcinomas: non-overlapping membrane expression in cell populations positive for both markers.J Histochem Cytochem59,441-55(2011)Immervoll, H., Hoem, D., Molven, A., Miletic, H., Steffensen, OJ.

RNA

ANXA4 mRNA [cytosol] (Homo sapiens)

- A Single-Cell Transcriptome Atlas of the Human Pancreas.Cell Syst3,385-394.e3(2016)Groen, N., van Gurp, L., Carlotti, F., van Oudenaarden, A., Dharmadhikari, G., Jansen, E., Muraro, MJ., Engelse, MA., Dielen, T., Grün, D., de Koning, EJ.
- Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.Genome Res27,208-222(2017)Stitzel, ML., George, J., Sivakamasundari, V., Kycia, I., Lawlor, N., Kursawe, R., Sun, L., Bolisetty, M., Robson, P.
- Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.Cell Metab24,593-607(2016)Andersson, EM., Ämmälä, C., Andréasson, AC., Picelli, S., Bjursell, MK., Sun, X., Sabirsh, A., Kasper, M., Clausen, M., Smith, DM., Eliasson, P., Palasantza, A., Segerstolpe, Å., Sandberg, R.
- Single-cell transcriptomic and spatial landscapes of the developing human pancreas.Cell Metab35,184-199.e5(2023)Kannambath, S., Olaniru, OE., Vaikkinen, H., Dhami, P., Persaud, SJ., Fung, K., Kadolsky, U.
- Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.EMBO Rep17,178-87(2016)Berishvili, E., Kubicek, S., Li, J., Bock, C., Klughammer, J., Spittler, A., Penz, T., Barbieux, C., Farlik, M.

CFTR mRNA [cytosol] (Homo sapiens)

- Deciphering early human pancreas development at the single-cell level.Nat Commun14,5354(2023)Zhang, X., Chen, X., Zhao, Y., Song, E., Zhong, W., Ma, Z., Xu, T., Yi, H., Ma, Y.
- A Single-Cell Transcriptome Atlas of the Human Pancreas.Cell Syst3,385-394.e3(2016)Groen, N., van Gurp, L., Carlotti, F., van Oudenaarden, A., Dharmadhikari, G., Jansen, E., Muraro, MJ., Engelse, MA., Dielen, T., Grün, D., de Koning, EJ.
- A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure.Cell Syst3,346-360.e4(2016)Gaujoux, R., Shen-Orr, SS., Klein, AM., Veres, A., Melton, DA., Wagner, BK., Baron, M., Yanai, I., Ryu, JH., Faust, AL., Vetere, A., Wolock, SL.
- Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.Genome Res27,208-222(2017)Stitzel, ML., George, J., Sivakamasundari, V., Kycia, I., Lawlor, N., Kursawe, R., Sun, L., Bolisetty, M., Robson, P.
- Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.Cell Metab24,593-607(2016)Andersson, EM., Ämmälä, C., Andréasson, AC., Picelli, S., Bjursell, MK., Sun, X., Sabirsh, A., Kasper, M., Clausen, M., Smith, DM., Eliasson, P., Palasantza, A., Segerstolpe, Å., Sandberg, R.
- Single-cell transcriptomic and spatial landscapes of the developing human pancreas.Cell Metab35,184-199.e5(2023)Kannambath, S., Olaniru, OE., Vaikkinen, H., Dhami, P., Persaud, SJ., Fung, K., Kadolsky, U.
- Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.Cell Metab35,1944-1960.e7(2023)Almaça, J., Pugliese, A., Qadir, MMF., Álvarez-Cubela, S., Klein, D., Fraker, CA., Ricordi, C., Altilio, I., Doke, M., Domínguez-Bendala, J., Pastori, RL., Schulz, J., Mateus Gonçalves, L.
- Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.EMBO Rep17,178-87(2016)Berishvili, E., Kubicek, S., Li, J., Bock, C., Klughammer, J., Spittler, A., Penz, T., Barbieux, C., Farlik, M.

ANXA3 mRNA [cytosol] (Homo sapiens)

- A Single-Cell Transcriptome Atlas of the Human Pancreas.Cell Syst3,385-394.e3(2016)Groen, N., van Gurp, L., Carlotti, F., van Oudenaarden, A., Dharmadhikari, G., Jansen, E., Muraro, MJ., Engelse, MA., Dielen, T., Grün, D., de Koning, EJ.
- Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.Cell Metab24,593-607(2016)Andersson, EM., Ämmälä, C., Andréasson, AC., Picelli, S., Bjursell, MK., Sun, X., Sabirsh, A., Kasper, M., Clausen, M., Smith, DM., Eliasson, P., Palasantza, A., Segerstolpe, Å., Sandberg, R.
- Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.Cell Metab35,1944-1960.e7(2023)Almaça, J., Pugliese, A., Qadir, MMF., Álvarez-Cubela, S., Klein, D., Fraker, CA., Ricordi, C., Altilio, I., Doke, M., Domínguez-Bendala, J., Pastori, RL., Schulz, J., Mateus Gonçalves, L.
- Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.EMBO Rep17,178-87(2016)Berishvili, E., Kubicek, S., Li, J., Bock, C., Klughammer, J., Spittler, A., Penz, T., Barbieux, C., Farlik, M.

ANXA9 mRNA [cytosol] (Homo sapiens)

- A Single-Cell Transcriptome Atlas of the Human Pancreas.Cell Syst3,385-394.e3(2016)Groen, N., van Gurp, L., Carlotti, F., van Oudenaarden, A., Dharmadhikari, G., Jansen, E., Muraro, MJ., Engelse, MA., Dielen, T., Grün, D., de Koning, EJ.
- Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.Genome Res27,208-222(2017)Stitzel, ML., George, J., Sivakamasundari, V., Kycia, I., Lawlor, N., Kursawe, R., Sun, L., Bolisetty, M., Robson, P.
- Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.EMBO Rep17,178-87(2016)Berishvili, E., Kubicek, S., Li, J., Bock, C., Klughammer, J., Spittler, A., Penz, T., Barbieux, C., Farlik, M.

ERICH5 mRNA [cytosol] (Homo sapiens)

- A Single-Cell Transcriptome Atlas of the Human Pancreas.Cell Syst3,385-394.e3(2016)Groen, N., van Gurp, L., Carlotti, F., van Oudenaarden, A., Dharmadhikari, G., Jansen, E., Muraro, MJ., Engelse, MA., Dielen, T., Grün, D., de Koning, EJ.

SLC4A4 mRNA [cytosol] (Homo sapiens)

- A Single-Cell Transcriptome Atlas of the Human Pancreas.Cell Syst3,385-394.e3(2016)Groen, N., van Gurp, L., Carlotti, F., van Oudenaarden, A., Dharmadhikari, G., Jansen, E., Muraro, MJ., Engelse, MA., Dielen, T., Grün, D., de Koning, EJ.
- Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.Genome Res27,208-222(2017)Stitzel, ML., George, J., Sivakamasundari, V., Kycia, I., Lawlor, N., Kursawe, R., Sun, L., Bolisetty, M., Robson, P.
- Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.Cell Metab35,1944-1960.e7(2023)Almaça, J., Pugliese, A., Qadir, MMF., Álvarez-Cubela, S., Klein, D., Fraker, CA., Ricordi, C., Altilio, I., Doke, M., Domínguez-Bendala, J., Pastori, RL., Schulz, J., Mateus Gonçalves, L.

KRT17 mRNA [cytosol] (Homo sapiens)

- A Single-Cell Transcriptome Atlas of the Human Pancreas.Cell Syst3,385-394.e3(2016)Groen, N., van Gurp, L., Carlotti, F., van Oudenaarden, A., Dharmadhikari, G., Jansen, E., Muraro, MJ., Engelse, MA., Dielen, T., Grün, D., de Koning, EJ.

SOX9 mRNA [cytosol] (Homo sapiens)

- A Single-Cell Transcriptome Atlas of the Human Pancreas.Cell Syst3,385-394.e3(2016)Groen, N., van Gurp, L., Carlotti, F., van Oudenaarden, A., Dharmadhikari, G., Jansen, E., Muraro, MJ., Engelse, MA., Dielen, T., Grün, D., de Koning, EJ.
- Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche.Proc Natl Acad Sci U S A117,10876-10887(2020)Lanzoni, G., Domínguez-Bendala, J., Johnson, K., Qadir, MMF., Navarro-Rubio, B., Pastori, RL., García, MT., Ricordi, C., van Dijk, J., Griswold, A., Klein, D., Díaz, Á., Muñiz-Anquela, R., Moreno-Hernández, YB., Sant, D., Álvarez-Cubela, S., Sadiq, S.

KRT23 mRNA [cytosol] (Homo sapiens)

- A Single-Cell Transcriptome Atlas of the Human Pancreas.Cell Syst3,385-394.e3(2016)Groen, N., van Gurp, L., Carlotti, F., van Oudenaarden, A., Dharmadhikari, G., Jansen, E., Muraro, MJ., Engelse, MA., Dielen, T., Grün, D., de Koning, EJ.
- Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.Cell Metab35,1944-1960.e7(2023)Almaça, J., Pugliese, A., Qadir, MMF., Álvarez-Cubela, S., Klein, D., Fraker, CA., Ricordi, C., Altilio, I., Doke, M., Domínguez-Bendala, J., Pastori, RL., Schulz, J., Mateus Gonçalves, L.

KRT19 mRNA [cytosol] (Homo sapiens)

- A Single-Cell Transcriptome Atlas of the Human Pancreas.Cell Syst3,385-394.e3(2016)Groen, N., van Gurp, L., Carlotti, F., van Oudenaarden, A., Dharmadhikari, G., Jansen, E., Muraro, MJ., Engelse, MA., Dielen, T., Grün, D., de Koning, EJ.
- Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.Genome Res27,208-222(2017)Stitzel, ML., George, J., Sivakamasundari, V., Kycia, I., Lawlor, N., Kursawe, R., Sun, L., Bolisetty, M., Robson, P.
- Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.Cell Metab24,593-607(2016)Andersson, EM., Ämmälä, C., Andréasson, AC., Picelli, S., Bjursell, MK., Sun, X., Sabirsh, A., Kasper, M., Clausen, M., Smith, DM., Eliasson, P., Palasantza, A., Segerstolpe, Å., Sandberg, R.
- Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.Cell Metab35,1944-1960.e7(2023)Almaça, J., Pugliese, A., Qadir, MMF., Álvarez-Cubela, S., Klein, D., Fraker, CA., Ricordi, C., Altilio, I., Doke, M., Domínguez-Bendala, J., Pastori, RL., Schulz, J., Mateus Gonçalves, L.
- Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche.Proc Natl Acad Sci U S A117,10876-10887(2020)Lanzoni, G., Domínguez-Bendala, J., Johnson, K., Qadir, MMF., Navarro-Rubio, B., Pastori, RL., García, MT., Ricordi, C., van Dijk, J., Griswold, A., Klein, D., Díaz, Á., Muñiz-Anquela, R., Moreno-Hernández, YB., Sant, D., Álvarez-Cubela, S., Sadiq, S.

PROM1 mRNA [cytosol] (Homo sapiens)

- CellMarker 2.0: an updated database of manually curated cell markers in human/mouse and web tools based on scRNA-seq data.Nucleic Acids Resnull,null(2022)Jiang, W., Li, T., Wang, P., Li, F., Zhang, X., Chen, J., Li, X., Xu, Y., Ou, Q., Hu, C., Zhang, Y., Bai, J., Yang, K.
- A Single-Cell Transcriptome Atlas of the Human Pancreas.Cell Syst3,385-394.e3(2016)Groen, N., van Gurp, L., Carlotti, F., van Oudenaarden, A., Dharmadhikari, G., Jansen, E., Muraro, MJ., Engelse, MA., Dielen, T., Grün, D., de Koning, EJ.
- Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.Genome Res27,208-222(2017)Stitzel, ML., George, J., Sivakamasundari, V., Kycia, I., Lawlor, N., Kursawe, R., Sun, L., Bolisetty, M., Robson, P.
- Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.EMBO Rep17,178-87(2016)Berishvili, E., Kubicek, S., Li, J., Bock, C., Klughammer, J., Spittler, A., Penz, T., Barbieux, C., Farlik, M.

ANXA1 mRNA [cytosol] (Homo sapiens)

- A Single-Cell Transcriptome Atlas of the Human Pancreas.Cell Syst3,385-394.e3(2016)Groen, N., van Gurp, L., Carlotti, F., van Oudenaarden, A., Dharmadhikari, G., Jansen, E., Muraro, MJ., Engelse, MA., Dielen, T., Grün, D., de Koning, EJ.

CA2 mRNA [cytosol] (Homo sapiens)

- A Single-Cell Transcriptome Atlas of the Human Pancreas.Cell Syst3,385-394.e3(2016)Groen, N., van Gurp, L., Carlotti, F., van Oudenaarden, A., Dharmadhikari, G., Jansen, E., Muraro, MJ., Engelse, MA., Dielen, T., Grün, D., de Koning, EJ.
- Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.EMBO Rep17,178-87(2016)Berishvili, E., Kubicek, S., Li, J., Bock, C., Klughammer, J., Spittler, A., Penz, T., Barbieux, C., Farlik, M.

TFPI2 mRNA [cytosol] (Homo sapiens)

- A Single-Cell Transcriptome Atlas of the Human Pancreas.Cell Syst3,385-394.e3(2016)Groen, N., van Gurp, L., Carlotti, F., van Oudenaarden, A., Dharmadhikari, G., Jansen, E., Muraro, MJ., Engelse, MA., Dielen, T., Grün, D., de Koning, EJ.
- Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.Genome Res27,208-222(2017)Stitzel, ML., George, J., Sivakamasundari, V., Kycia, I., Lawlor, N., Kursawe, R., Sun, L., Bolisetty, M., Robson, P.
- Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.EMBO Rep17,178-87(2016)Berishvili, E., Kubicek, S., Li, J., Bock, C., Klughammer, J., Spittler, A., Penz, T., Barbieux, C., Farlik, M.

CLDN10 mRNA [cytosol] (Homo sapiens)

- A Single-Cell Transcriptome Atlas of the Human Pancreas.Cell Syst3,385-394.e3(2016)Groen, N., van Gurp, L., Carlotti, F., van Oudenaarden, A., Dharmadhikari, G., Jansen, E., Muraro, MJ., Engelse, MA., Dielen, T., Grün, D., de Koning, EJ.
- Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.Cell Metab24,593-607(2016)Andersson, EM., Ämmälä, C., Andréasson, AC., Picelli, S., Bjursell, MK., Sun, X., Sabirsh, A., Kasper, M., Clausen, M., Smith, DM., Eliasson, P., Palasantza, A., Segerstolpe, Å., Sandberg, R.
- Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.Cell Metab35,1944-1960.e7(2023)Almaça, J., Pugliese, A., Qadir, MMF., Álvarez-Cubela, S., Klein, D., Fraker, CA., Ricordi, C., Altilio, I., Doke, M., Domínguez-Bendala, J., Pastori, RL., Schulz, J., Mateus Gonçalves, L.

HNF1B mRNA [cytosol] (Homo sapiens)

- A Single-Cell Transcriptome Atlas of the Human Pancreas.Cell Syst3,385-394.e3(2016)Groen, N., van Gurp, L., Carlotti, F., van Oudenaarden, A., Dharmadhikari, G., Jansen, E., Muraro, MJ., Engelse, MA., Dielen, T., Grün, D., de Koning, EJ.

CD74 mRNA [cytosol] (Homo sapiens)

- A Single-Cell Transcriptome Atlas of the Human Pancreas.Cell Syst3,385-394.e3(2016)Groen, N., van Gurp, L., Carlotti, F., van Oudenaarden, A., Dharmadhikari, G., Jansen, E., Muraro, MJ., Engelse, MA., Dielen, T., Grün, D., de Koning, EJ.
- Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.Genome Res27,208-222(2017)Stitzel, ML., George, J., Sivakamasundari, V., Kycia, I., Lawlor, N., Kursawe, R., Sun, L., Bolisetty, M., Robson, P.
- Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.EMBO Rep17,178-87(2016)Berishvili, E., Kubicek, S., Li, J., Bock, C., Klughammer, J., Spittler, A., Penz, T., Barbieux, C., Farlik, M.

ANXA2 mRNA [cytosol] (Homo sapiens)

- A Single-Cell Transcriptome Atlas of the Human Pancreas.Cell Syst3,385-394.e3(2016)Groen, N., van Gurp, L., Carlotti, F., van Oudenaarden, A., Dharmadhikari, G., Jansen, E., Muraro, MJ., Engelse, MA., Dielen, T., Grün, D., de Koning, EJ.
- Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.Cell Metab24,593-607(2016)Andersson, EM., Ämmälä, C., Andréasson, AC., Picelli, S., Bjursell, MK., Sun, X., Sabirsh, A., Kasper, M., Clausen, M., Smith, DM., Eliasson, P., Palasantza, A., Segerstolpe, Å., Sandberg, R.
- Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.Cell Metab35,1944-1960.e7(2023)Almaça, J., Pugliese, A., Qadir, MMF., Álvarez-Cubela, S., Klein, D., Fraker, CA., Ricordi, C., Altilio, I., Doke, M., Domínguez-Bendala, J., Pastori, RL., Schulz, J., Mateus Gonçalves, L.
- Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.EMBO Rep17,178-87(2016)Berishvili, E., Kubicek, S., Li, J., Bock, C., Klughammer, J., Spittler, A., Penz, T., Barbieux, C., Farlik, M.

AQP1 mRNA [cytosol] (Homo sapiens)

- A Single-Cell Transcriptome Atlas of the Human Pancreas.Cell Syst3,385-394.e3(2016)Groen, N., van Gurp, L., Carlotti, F., van Oudenaarden, A., Dharmadhikari, G., Jansen, E., Muraro, MJ., Engelse, MA., Dielen, T., Grün, D., de Koning, EJ.
- Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.Cell Metab24,593-607(2016)Andersson, EM., Ämmälä, C., Andréasson, AC., Picelli, S., Bjursell, MK., Sun, X., Sabirsh, A., Kasper, M., Clausen, M., Smith, DM., Eliasson, P., Palasantza, A., Segerstolpe, Å., Sandberg, R.
- Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.Cell Metab35,1944-1960.e7(2023)Almaça, J., Pugliese, A., Qadir, MMF., Álvarez-Cubela, S., Klein, D., Fraker, CA., Ricordi, C., Altilio, I., Doke, M., Domínguez-Bendala, J., Pastori, RL., Schulz, J., Mateus Gonçalves, L.
- Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.EMBO Rep17,178-87(2016)Berishvili, E., Kubicek, S., Li, J., Bock, C., Klughammer, J., Spittler, A., Penz, T., Barbieux, C., Farlik, M.

KRT7 mRNA [cytosol] (Homo sapiens)

- A Single-Cell Transcriptome Atlas of the Human Pancreas.Cell Syst3,385-394.e3(2016)Groen, N., van Gurp, L., Carlotti, F., van Oudenaarden, A., Dharmadhikari, G., Jansen, E., Muraro, MJ., Engelse, MA., Dielen, T., Grün, D., de Koning, EJ.
- Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.Cell Metab35,1944-1960.e7(2023)Almaça, J., Pugliese, A., Qadir, MMF., Álvarez-Cubela, S., Klein, D., Fraker, CA., Ricordi, C., Altilio, I., Doke, M., Domínguez-Bendala, J., Pastori, RL., Schulz, J., Mateus Gonçalves, L.
- Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.EMBO Rep17,178-87(2016)Berishvili, E., Kubicek, S., Li, J., Bock, C., Klughammer, J., Spittler, A., Penz, T., Barbieux, C., Farlik, M.

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Trunk bipotent pancreatic progenitor cell produces pancreatic ductal cell (Homo sapiens)

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