Reactome | p-S43,S744-FIRRM [cytosol]

p-S43,S744-FIRRM [cytosol]

Stable Identifier

R-HSA-9853437

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

p-S43,S744-Apolo1

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9NSG2 FIRRM

Gene Names

FIRRM, APOLO1, C1orf112

Chain

chain:1-853

Reference Genes

BioGPS Gene:55732 FIRRM

COSMIC (genes):C1orf112 FIRRM

CTD Gene:55732 FIRRM

dbSNP Gene:55732 FIRRM

ENSEMBL:ENSG00000000460 FIRRM

HGNC:25565 FIRRM

KEGG:hsa:55732 FIRRM

Monarch:55732 FIRRM

NCBI Gene:55732 FIRRM

UCSC:Q9NSG2 FIRRM

Reference Transcript

Other Identifiers

11725837_a_at

11747369_x_at

11752665_a_at

16673557

220840_PM_s_at

220840_s_at

2366582

2366583

2366584

2366594

2366595

2366596

2366597

2366598

2366599

2366600

2366601

2366602

2366603

2366604

2366606

2366607

2366608

2366609

2366610

2366611

2366614

2366615

2366621

2366622

2366623

2366624

2366625

2366626

2366627

2366628

2366629

2366630

2366631

2366635

2366636

2366637

2366638

2366639

2366640

2366641

2366642

2366643

2366644

2366645

2366646

2366647

2366651

2366652

2366653

2366654

2366655

2366661

34754_at

3551121

55732

7907183

A_14_P110548

A_14_P116543

A_14_P117149

A_23_P11862

GE82320

GO:0000278

GO:0000775

GO:0000776

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005730

GO:0005737

GO:0005819

GO:0005829

GO:0005856

GO:0007059

GO:0019901

GO:0030496

GO:0036297

GO:0043226

GO:0045859

GO:0051233

HMNXSV003032151

ILMN_1727540

PH_hs_0021261

TC01001476.hg

g8922604_3p_a_at

Participates

as an output of

PLK1 phosphorylates FIRMM at S744 (Homo sapiens)

Other forms of this molecule

FIRRM [nucleoplasm]

p-S43-FIRRM [cytosol]

FIRRM [cytosol]

Inferred To

phospho-FIRRM [cytosol] (Bos taurus)

phospho-FIRRM [cytosol] (Canis familiaris)

phospho-FIRRM [cytosol] (Gallus gallus)

phospho-FIRRM [cytosol] (Sus scrofa)

phospho-firrm [cytosol] (Danio rerio)

phospho-Firrm [cytosol] (Mus musculus)

phospho-Firrm [cytosol] (Rattus norvegicus)

Modified Residues

Name

O-phospho-L-serine at 43

Coordinate

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-serine at 744

Coordinate

744

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Cross References

RefSeq

XP_016857214.1, NP_001306980.1, NP_060656.2, NP_001353701.1, XP_047280715.1, NP_001353700.1, XP_047280718.1, XP_047280716.1, NP_001306976.1, XP_054193542.1, XP_054193549.1, XP_054193543.1, NP_001306977.1, NP_001350668.1, NP_001353702.1, XP_016857213.1, XP_054193544.1, XP_054193545.1, XP_054193546.1, NP_001306979.1, XP_047280699.1, XP_047280727.1, XP_011508037.1, XP_047280707.1, XP_047280708.1

OpenTargets

ENSG00000000460

ENSEMBL

ENSP00000389257, ENSP00000352276, ENSG00000000460, ENST00000413811, ENSP00000286031, ENST00000359326, ENST00000286031

HPA

ENSG00000000460-C1orf112

GeneCards

FIRRM

PRO

Q9NSG2

Pharos - Targets

Q9NSG2

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q6PIW4 FIGNL1	1	FIGNL1 [nucleoplasm] (R-HSA-9853365)	0.564	6
UniProt:Q7Z4N8 P4HA3	1	P4HA3 [endoplasmic reticulum lumen] (R-HSA-2980915)	0.556	3
UniProt:Q13304 GPR17	1	GPR17 [plasma membrane] (R-HSA-416429)	0.527	3
UniProt:Q86VZ1 P2RY8			0.527	3
UniProt:Q8N7X8 SIGL1			0.527	2
UniProt:Q96PE5 OPALI			0.527	2
UniProt:P41587 VIPR2	1	VIPR2 [plasma membrane] (R-HSA-420227)	0.527	3
UniProt:O95977 S1PR4	1	S1PR4 [plasma membrane] (R-HSA-419347)	0.527	2
UniProt:P25942 CD40			0.527	2
UniProt:Q8TDB4 HUMMR			0.527	2