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SDHAF4 [mitochondrial matrix]
Stable Identifier
R-HSA-9854972
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial matrix
Locations in the PathwayBrowser for interactor UniProt:O75841 UPK1B
Expand all
Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Citric acid cycle (TCA cycle) (Homo sapiens)
Maturation of TCA enzymes and regulation of TCA cycle (Homo sapiens)
SDHA binds to SDHB (Homo sapiens)
SDHAF4 [mitochondrial matrix] (Homo sapiens)
SDHAF4 binds to FAD-SDHA (Homo sapiens)
SDHAF4 [mitochondrial matrix] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q5VUM1 SDHAF4
Gene Names
SDHAF4, C6orf57
Chain
transit peptide:1-20, chain:21-108
Reference Genes
BioGPS Gene:135154 SDHAF4
COSMIC (genes):SDHAF4 SDHAF4
CTD Gene:135154 SDHAF4
dbSNP Gene:135154 SDHAF4
ENSEMBL:ENSG00000154079 SDHAF4
HGNC:20957 SDHAF4
KEGG:hsa:135154 SDHAF4
Monarch:135154 SDHAF4
NCBI Gene:135154 SDHAF4
OMIM:619198 SDHAF4
UCSC:Q5VUM1 SDHAF4
Reference Transcript
RefSeq:NM_145267.2 SDHAF4
Other Identifiers
11730451_at
11759032_at
135154
17010147
238504_PM_at
238504_at
2912861
2912862
2912865
2912868
2912869
2912870
2912871
8120579
91298_at
A_14_P138193
A_23_P256279
A_33_P3361417
GE87340
GO:0002376
GO:0003674
GO:0005515
GO:0005575
GO:0005739
GO:0005759
GO:0006091
GO:0006099
GO:0006457
GO:0008047
GO:0034553
GO:0043226
GO:0044183
GO:0045087
GO:0045333
GO:0065003
GO:0098542
GO:0098772
HMNXSV003000582
Hs.71367.0.S1_3p_at
ILMN_1728057
PH_hs_0033259
TC06000717.hg
Participates
as an output of
SDHA binds to SDHB (Homo sapiens)
as a component of
FAD-SDHA:SDHAF4 [mitochondrial matrix] (Homo sapiens)
as an input of
SDHAF4 binds to FAD-SDHA (Homo sapiens)
Inferred To
SDH8 [mitochondrial matrix]
(Saccharomyces cerevisiae)
Sdhaf4 [mitochondrial matrix]
(Mus musculus)
A0A1D5PX55 [mitochondrial matrix]
(Gallus gallus)
Dmel\CG15283 [mitochondrial matrix]
(Drosophila melanogaster)
Q8MQG6 [mitochondrial matrix]
(Caenorhabditis elegans)
sdhaf4 [mitochondrial matrix]
(Danio rerio)
sdhaf4 [mitochondrial matrix]
(Xenopus tropicalis)
C6Y4C4 [mitochondrial matrix]
(Schizosaccharomyces pombe)
F6QGP7 [mitochondrial matrix]
(Bos taurus)
SDHAF4 [mitochondrial matrix]
(Canis familiaris)
SDHAF4 [mitochondrial matrix]
(Sus scrofa)
Q54Y25 [mitochondrial matrix]
(Dictyostelium discoideum)
Cross References
RefSeq
NP_660310.2
ENSEMBL
ENSP00000359505
,
ENST00000370474
OpenTargets
ENSG00000154079
HPA
ENSG00000154079-SDHAF4
PRO
Q5VUM1
Pharos - Targets
Q5VUM1
PDB
8DYE
,
8DYD
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O43169 CYB5B
2
CYB5B [endoplasmic reticulum membrane]
(R-HSA-9842695)
CYB5B [mitochondrial outer membrane]
(R-HSA-8943390)
0.556
3
UniProt:P60033 CD81
1
CD81 [plasma membrane]
(R-HSA-197933)
0.556
3
UniProt:O75841 UPK1B
0.556
3
UniProt:Q9NRP4 SDHAF3
1
SDHAF3 [mitochondrial matrix]
(R-HSA-9855015)
0.527
2
UniProt:P31040 SDHA
2
FAD-SDHA [mitochondrial matrix]
(R-HSA-70983)
SDHA [mitochondrial matrix]
(R-HSA-9854690)
0.527
3
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