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TFE3 [nucleoplasm]
Stable Identifier
R-HSA-9857366
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
fullName evidence="20"Transcription factor E3, TFE3_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
MITF-M-regulated melanocyte development (Homo sapiens)
MITF-M-dependent gene expression (Homo sapiens)
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence (Homo sapiens)
MITF-M-dependent MCM5 gene expression (Homo sapiens)
MITF dimer [nucleoplasm] (Homo sapiens)
MITF,TFE3,TFEB,TFEC [nucleoplasm] (Homo sapiens)
TFE3 [nucleoplasm] (Homo sapiens)
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation (Homo sapiens)
MITF-M-dependent CDC25B gene expression (Homo sapiens)
MITF dimer [nucleoplasm] (Homo sapiens)
MITF,TFE3,TFEB,TFEC [nucleoplasm] (Homo sapiens)
TFE3 [nucleoplasm] (Homo sapiens)
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition (Homo sapiens)
MITF-M-dependent CDH1 gene expression (Homo sapiens)
MITF dimer [nucleoplasm] (Homo sapiens)
MITF,TFE3,TFEB,TFEC [nucleoplasm] (Homo sapiens)
TFE3 [nucleoplasm] (Homo sapiens)
MITF-M-dependent GXYLT2 gene expression (Homo sapiens)
MITF dimer [nucleoplasm] (Homo sapiens)
MITF,TFE3,TFEB,TFEC [nucleoplasm] (Homo sapiens)
TFE3 [nucleoplasm] (Homo sapiens)
MITF-M-dependent SOX2 gene expression (Homo sapiens)
MITF dimer [nucleoplasm] (Homo sapiens)
MITF,TFE3,TFEB,TFEC [nucleoplasm] (Homo sapiens)
TFE3 [nucleoplasm] (Homo sapiens)
MITF-M-dependent STT3B gene expression (Homo sapiens)
MITF dimer [nucleoplasm] (Homo sapiens)
MITF,TFE3,TFEB,TFEC [nucleoplasm] (Homo sapiens)
TFE3 [nucleoplasm] (Homo sapiens)
MITF-M-dependent ZEB1 gene expression (Homo sapiens)
MITF dimer [nucleoplasm] (Homo sapiens)
MITF,TFE3,TFEB,TFEC [nucleoplasm] (Homo sapiens)
TFE3 [nucleoplasm] (Homo sapiens)
Transcriptional and post-translational regulation of MITF-M expression and activity (Homo sapiens)
MITF dimerizes (Homo sapiens)
MITF dimer [nucleoplasm] (Homo sapiens)
MITF,TFE3,TFEB,TFEC [nucleoplasm] (Homo sapiens)
TFE3 [nucleoplasm] (Homo sapiens)
MITF,TFE3,TFEB,TFEC [nucleoplasm] (Homo sapiens)
TFE3 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P19532 TFE3
Gene Names
TFE3, BHLHE33
Chain
chain:1-575
Reference Genes
BioGPS Gene:7030 TFE3
COSMIC (genes):TFE3 TFE3
CTD Gene:7030 TFE3
dbSNP Gene:7030 TFE3
ENSEMBL:ENSG00000068323 TFE3
HGNC:11752 TFE3
KEGG:hsa:7030 TFE3
Monarch:7030 TFE3
NCBI Gene:7030 TFE3
OMIM:314310 TFE3
UCSC:P19532 TFE3
Reference Transcript
RefSeq:NM_001282142.1 TFE3
RefSeq:NM_006521.5 TFE3
Other Identifiers
11743855_a_at
11748029_a_at
1565347_PM_s_at
1565347_s_at
17110745
206649_PM_s_at
206649_s_at
212457_PM_at
212457_at
34669_at
3959680
4007735
4007736
4007737
4007738
4007739
4007740
4007741
4007742
4007743
4007745
4007746
4007747
4007748
4007750
4007751
4007752
4007753
4007754
4007755
4007757
4007758
4007759
4007760
7030
7895004
8172520
A_23_P84952
A_33_P3370076
GE79190
GO:0000785
GO:0000976
GO:0000978
GO:0000981
GO:0001228
GO:0002250
GO:0002376
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005764
GO:0005765
GO:0005773
GO:0005829
GO:0006355
GO:0006357
GO:0006959
GO:0007040
GO:0016020
GO:0043226
GO:0045670
GO:0045785
GO:0045893
GO:0045944
GO:0046983
GO:0090336
GO:0120163
GO:0140110
GO:1990837
HMNXSV003039582
Hs2.433687.1.S1_3p_s_at
ILMN_1764826
PH_hs_0014125
TC0X001025.hg
X97160_rna1_at
g8659573_3p_a_at
Participates
as a member of
MITF,TFE3,TFEB,TFEC [nucleoplasm] (Homo sapiens)
Cross References
RefSeq
NP_006512.2
,
NP_001269071.1
ENSEMBL
ENST00000493583
,
ENSP00000314129
,
ENSG00000292217
,
ENST00000315869
,
ENST00000710095
,
ENST00000710096
,
ENSP00000476976
,
ENSP00000518054
,
ENSP00000518055
,
ENSG00000068323
OpenTargets
ENSG00000068323
GeneCards
TFE3
HPA
ENSG00000068323-TFE3
PRO
P19532
Pharos - Targets
P19532
GlyGen
P19532
Orphanet
TFE3
PDB
7F09
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P19484 TFEB
1
TFEB [nucleoplasm]
(R-HSA-9857368)
0.643
4
UniProt:O75030 MITF
2
MITF [nucleoplasm]
(R-HSA-201592)
monoSUMO1-K289,423-MITF [nucleoplasm]
(R-HSA-3232153)
0.564
2
UniProt:Q9UHA4 LAMTOR3
5
LAMTOR3 [lysosomal membrane]
(R-HSA-5653581)
LAMTOR3 [endosome membrane]
(R-HSA-5693294)
LAMTOR3 [specific granule membrane]
(R-HSA-6800178)
LAMTOR3 [plasma membrane]
(R-HSA-6806307)
LAMTOR3 [tertiary granule membrane]
(R-HSA-6800189)
0.556
3
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