Reactome | TMEM223 [mitochondrial inner membrane]

TMEM223 [mitochondrial inner membrane]

Stable Identifier

R-HSA-9865797

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Locations in the PathwayBrowser for interactor UniProt:P10321 HLA-C

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External Reference Information

External Reference

UniProt:A0PJW6 TMEM223

Gene Names

TMEM223

Chain

chain:1-202

Reference Genes

BioGPS Gene:79064 TMEM223

COSMIC (genes):TMEM223 TMEM223

CTD Gene:79064 TMEM223

dbSNP Gene:79064 TMEM223

ENSEMBL:ENSG00000168569 TMEM223

HGNC:28464 TMEM223

KEGG:hsa:79064 TMEM223

Monarch:79064 TMEM223

NCBI Gene:79064 TMEM223

OMIM:620434 TMEM223

UCSC:A0PJW6 TMEM223

Reference Transcript

RefSeq:NM_001080501.2 TMEM223

Other Identifiers

11742713_at

16739543

213818_PM_x_at

213818_x_at

213961_PM_s_at

213961_s_at

220934_PM_s_at

220934_s_at

238981_PM_at

238981_at

242213_PM_at

242213_at

3376136

3376138

3376139

3376141

3376142

3376145

3376146

3376147

3376149

3376150

3376153

3376154

39907_at

44091_at

44751_at

79064

7948836

82203_at

88144_at

A_23_P1956

GE58079

GE82793

GO:0005739

GO:0005743

GO:0007399

GO:0016020

GO:0033617

GO:0043226

GO:0048856

GO:0065003

GO:0097177

HMNXSV003045146

HMNXSV003052152

Hs.131846.0.A1_3p_s_at

Hs.132445.0.A1_3p_at

Hs.146428.3.A1_3p_a_at

Hs.22792.0.A1_3p_at

ILMN_1722674

ILMN_2263144

PH_hs_0036151

TC11001879.hg

g13129079_3p_a_at

p2324

This entity regulates

Positively

MT-CO1 mRNA is translated (Homo sapiens)

Cross References

ENSEMBL

ENSP00000303987, ENST00000307366

OpenTargets

ENSG00000168569

HPA

ENSG00000168569-TMEM223

PRO

A0PJW6

Pharos - Targets

A0PJW6

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8NFQ8 TOIP2			0.527	2
UniProt:Q9H8X2 IPPK	2	IPPK [cytosol] (R-HSA-1604598) IPPK [nucleoplasm] (R-HSA-2023949)	0.527	2
UniProt:P08473 MME	2	MME [secretory granule membrane] (R-HSA-6806156) MME [plasma membrane] (R-HSA-2022342)	0.527	2
UniProt:P30825 SLC7A1	1	SLC7A1 [plasma membrane] (R-HSA-375771)	0.527	2
UniProt:Q13061 TRDN	1	TRDN [sarcoplasmic reticulum lumen] (R-HSA-2855215)	0.527	3
UniProt:P10321 HLA-C	8	HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [phagocytic vesicle membrane] (R-HSA-1236760) HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [recycling endosome membrane] (R-HSA-8863915) HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [early endosome membrane] (R-HSA-1236799) HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [ER to Golgi transport vesicle membrane] (R-HSA-983354) HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [Golgi membrane] (R-HSA-983387) HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [plasma membrane] (R-HSA-199595) HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [secretory granule membrane] (R-HSA-6803292) HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [lumenal side of endoplasmic reticulum membrane] (R-HSA-983044)	0.527	2
UniProt:P22460 KCNA5	1	KCNA5 [plasma membrane] (R-HSA-977472)	0.527	2
UniProt:P42898 MTHFR	1	MTHFR [cytosol] (R-HSA-200663)	0.527	2
UniProt:Q53GT1 KLHL22	1	KLHL22 [cytosol] (R-HSA-8863210)	0.527	2
UniProt:Q6ZMH5 SLC39A5	1	SLC39A5 [plasma membrane] (R-HSA-442360)	0.527	2

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