Reactome | PSMG3 [cytosol]

PSMG3 [cytosol]

Stable Identifier

R-HSA-9908033

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Proteasome assembly chaperone 3, PSMG3_HUMAN, PAC3, Yeast Pba3 ortholog

Locations in the PathwayBrowser for interactor UniProt:Q9UDW3 ZMAT5

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External Reference Information

External Reference

UniProt:Q9BT73 PSMG3

Gene Names

PSMG3, C7orf48, PAC3

Chain

chain:1-122

Reference Genes

BioGPS Gene:84262 PSMG3

COSMIC (genes):PSMG3 PSMG3

CTD Gene:84262 PSMG3

dbSNP Gene:84262 PSMG3

ENSEMBL:ENSG00000157778 PSMG3

HGNC:22420 PSMG3

KEGG:hsa:84262 PSMG3

Monarch:84262 PSMG3

NCBI Gene:84262 PSMG3

OMIM:617528 PSMG3

UCSC:Q9BT73 PSMG3

Reference Transcript

Other Identifiers

11716555_at

17054460

223363_PM_at

223363_at

3035409

3035410

3035411

3035412

3035413

3035414

3035415

3035416

8137798

84262

91671_at

A_24_P21044

GE83369

GO:0005515

GO:0032991

GO:0043248

GO:0044877

GO:0051131

GO:0060090

GO:0065003

HMNXSV003045712

ILMN_1802627

PH_hs_0026083

TC07001088.hg

g13279190_3p_at

Participates

as an input of

PSMG3 binds PSMG4 (Homo sapiens)

as a component of

PSMG3:PSMG4 [cytosol] (Homo sapiens)

Inferred To

psmg3 [cytosol] (Danio rerio)

psmg3 [cytosol] (Xenopus tropicalis)

BcDNA:AT13539 [cytosol] (Drosophila melanogaster)

psmG3 [cytosol] (Dictyostelium discoideum)

Ghost homologue of PSMG3 [cytosol] (Plasmodium falciparum)

Ghost homologue of PSMG3 [cytosol] (Saccharomyces cerevisiae)

PSMG3 [cytosol] (Bos taurus)

PSMG3 [cytosol] (Canis familiaris)

PSMG3 [cytosol] (Gallus gallus)

PSMG3 [cytosol] (Schizosaccharomyces pombe)

PSMG3 [cytosol] (Sus scrofa)

Psmg3 [cytosol] (Rattus norvegicus)

mPsmg3 [cytosol] (Mus musculus)

Cross References

OpenTargets

ENSG00000157778

ENSEMBL

ENST00000404674, ENSP00000288607, ENSP00000252329, ENSP00000384799, ENSG00000157778, ENST00000288607, ENST00000252329

HPA

ENSG00000157778-PSMG3

GeneCards

PSMG3

ZINC - Substances

PSMG3_HUMAN

ZINC target

Q9BT73

PRO

Q9BT73

Pharos - Targets

Q9BT73

GlyGen

Q9BT73

ZINC - Predictions - Purchasable

PSMG3_HUMAN

PDB

8QYJ, 6JPT, 2Z5E, 8TM3

Interactors (22)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q969U7 PSMG2	1	PSMG2 [cytosol] (R-HSA-9908053)	0.643	5
UniProt:P28065 PSMB9	3	PSMB9 [cytosol] (R-HSA-68765) pro-PSMB9 [cytosol] (R-HSA-9908136) PSMB9(1-20) [cytosol] (R-HSA-9908132)	0.643	5
UniProt:Q8NAJ2 CI106			0.589	2
UniProt:P25786 PSMA1	2	PSMA1 [cytosol] (R-HSA-68724) PSMA1 [nucleoplasm] (R-HSA-174333)	0.569	6
UniProt:P49720 PSMB3	2	PSMB3 [cytosol] (R-HSA-68747) PSMB3 [nucleoplasm] (R-HSA-174341)	0.527	3
UniProt:Q12950 FOXD4			0.527	3
UniProt:Q9BQB4 SOST	1	SOST [extracellular region] (R-HSA-3769322)	0.527	2
UniProt:Q9NPC8 SIX2	1	SIX2 [nucleoplasm] (R-HSA-9831037)	0.527	3
UniProt:Q9NS85 CAH10			0.527	3
UniProt:O43674 NDUFB5	1	NDUFB5 [mitochondrial inner membrane] (R-HSA-163944)	0.527	3
UniProt:P25787 PSMA2	5	PSMA2 [cytosol] (R-HSA-68726) PSMA2 [nucleoplasm] (R-HSA-174345) PSMA2 [ficolin-1-rich granule lumen] (R-HSA-6803285) PSMA2 [extracellular region] (R-HSA-6806506) PSMA2 [secretory granule lumen] (R-HSA-6803329)	0.527	4
UniProt:Q6RVD6 SPAT8			0.527	2
UniProt:Q9UDW3 ZMAT5	1	ZMAT5 [nucleoplasm] (R-HSA-6787850)	0.527	3
UniProt:P28066 PSMA5	5	PSMA5 [cytosol] (R-HSA-68732) PSMA5 [nucleoplasm] (R-HSA-174340) PSMA5 [ficolin-1-rich granule lumen] (R-HSA-6803328) PSMA5 [extracellular region] (R-HSA-6806459) PSMA5 [secretory granule lumen] (R-HSA-6803316)	0.527	4
UniProt:P24592 IGFBP6	1	IGFBP6 [extracellular region] (R-HSA-381475)	0.527	2
UniProt:P62280 RPS11	2	RPS11 [cytosol] (R-HSA-72327) RPS11 [nucleoplasm] (R-HSA-6791212)	0.527	2
UniProt:Q8TCI5 CMAP3			0.527	2
UniProt:Q96S79 RSLAB			0.527	3
UniProt:Q99436 PSMB7	7	PSMB7 [cytosol] (R-HSA-68759) PSMB7 [nucleoplasm] (R-HSA-174331) pro-PSMB7 [cytosol] (R-HSA-9908145) PSMB7(1-43) [cytosol] (R-HSA-9908129) PSMB7 [ficolin-1-rich granule lumen] (R-HSA-6803312) PSMB7 [extracellular region] (R-HSA-6806449) PSMB7 [secretory granule lumen] (R-HSA-6803279)	0.527	3
UniProt:P82930 MRPS34	1	MRPS34 [mitochondrial inner membrane] (R-HSA-5368186)	0.527	3
UniProt:O14818 PSMA7	2	PSMA7 [cytosol] (R-HSA-68736) PSMA7 [nucleoplasm] (R-HSA-174351)	0.527	2
UniProt:P61289 PSME3	1	PSME3 [cytosol] (R-HSA-68816)	0.527	2

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