Reactome | PSMG4 [cytosol]

PSMG4 [cytosol]

Stable Identifier

R-HSA-9908036

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Proteasome assembly chaperone 4, PSMG4_HUMAN, PAC4, Yeast Pba4 ortholog

Locations in the PathwayBrowser for interactor UniProt:Q9UDW3 ZMAT5

Expand all

External Reference Information

External Reference

UniProt:Q5JS54 PSMG4

Gene Names

PSMG4, C6orf86, PAC4

Chain

chain:1-123

Reference Genes

BioGPS Gene:389362 PSMG4

COSMIC (genes):PSMG4 PSMG4

CTD Gene:389362 PSMG4

dbSNP Gene:389362 PSMG4

ENSEMBL:ENSG00000180822 PSMG4

HGNC:21108 PSMG4

KEGG:hsa:389362 PSMG4

Monarch:389362 PSMG4

NCBI Gene:389362 PSMG4

OMIM:617550 PSMG4

UCSC:Q5JS54 PSMG4

Reference Transcript

Other Identifiers

11731252_a_at

11738272_a_at

11738273_at

11738274_x_at

11743499_a_at

11743500_x_at

17004342

228217_PM_s_at

228217_s_at

233443_PM_at

233443_at

242623_PM_x_at

242623_x_at

2892454

2892455

2892456

2892457

2892458

2892460

2892461

2892462

2892463

2892465

2892466

2892467

2892468

2892469

2892470

2892471

2892472

2892473

2892474

2892475

2892476

2892477

2892478

2892479

2892480

2892481

2892482

2892486

2892487

2892489

2892490

2892492

2892494

2892506

389362

76063_s_at

78289_at

8116655

84862_at

90030_at

A_14_P123665

A_33_P3259053

A_33_P3259058

A_33_P3390960

GE833485

GE87623

GO:0032991

GO:0043248

GO:0044877

GO:0065003

HMNXSV003000301

HMNXSV003033975

HMNXSV003048309

Hs.175382.0.A1_3p_at

Hs.284298.0.S1_3p_a_at

PH_hs_0038307

TC06002472.hg

TC06002474.hg

p33824

Participates

as an input of

PSMG3 binds PSMG4 (Homo sapiens)

as a component of

PSMG3:PSMG4 [cytosol] (Homo sapiens)

Inferred To

mPsmg4 [cytosol] (Mus musculus)

Ghost homologue of PSMG4 [cytosol] (Danio rerio)

Ghost homologue of PSMG4 [cytosol] (Saccharomyces cerevisiae)

psmg4 [cytosol] (Xenopus tropicalis)

Psmg4 [cytosol] (Rattus norvegicus)

PSMG4 [cytosol] (Bos taurus)

PSMG4 [cytosol] (Canis familiaris)

PSMG4 [cytosol] (Gallus gallus)

PSMG4 [cytosol] (Plasmodium falciparum)

PSMG4 [cytosol] (Schizosaccharomyces pombe)

PSMG4 [cytosol] (Sus scrofa)

BcDNA:GH19585 [cytosol] (Drosophila melanogaster)

psmG4 [cytosol] (Dictyostelium discoideum)

Cross References

ENSEMBL

ENSP00000413353, ENST00000438998, ENSP00000392353, ENSG00000180822, ENST00000473000, ENST00000419065, ENSP00000418241

OpenTargets

ENSG00000180822

GeneCards

PSMG4

HPA

ENSG00000180822-PSMG4

PRO

Q5JS54

Pharos - Targets

Q5JS54

GlyGen

Q5JS54

PDB

5WTQ, 8QYJ, 8TM3

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q969U7 PSMG2	1	PSMG2 [cytosol] (R-HSA-9908053)	0.643	4
UniProt:P25786 PSMA1	2	PSMA1 [cytosol] (R-HSA-68724) PSMA1 [nucleoplasm] (R-HSA-174333)	0.569	5
UniProt:A2VCK2 DCD2B			0.527	2
UniProt:Q9NS85 CAH10			0.527	2
UniProt:P82930 MRPS34	1	MRPS34 [mitochondrial inner membrane] (R-HSA-5368186)	0.527	3
UniProt:Q9NV31 IMP3	1	IMP3 [nucleoplasm] (R-HSA-6790664)	0.527	3
UniProt:Q9UDW3 ZMAT5	1	ZMAT5 [nucleoplasm] (R-HSA-6787850)	0.527	2
UniProt:Q12950 FOXD4			0.527	3
UniProt:P28066 PSMA5	5	PSMA5 [cytosol] (R-HSA-68732) PSMA5 [nucleoplasm] (R-HSA-174340) PSMA5 [ficolin-1-rich granule lumen] (R-HSA-6803328) PSMA5 [extracellular region] (R-HSA-6806459) PSMA5 [secretory granule lumen] (R-HSA-6803316)	0.527	4
UniProt:P28065 PSMB9	3	PSMB9 [cytosol] (R-HSA-68765) pro-PSMB9 [cytosol] (R-HSA-9908136) PSMB9(1-20) [cytosol] (R-HSA-9908132)	0.527	4
UniProt:P25787 PSMA2	5	PSMA2 [cytosol] (R-HSA-68726) PSMA2 [nucleoplasm] (R-HSA-174345) PSMA2 [ficolin-1-rich granule lumen] (R-HSA-6803285) PSMA2 [extracellular region] (R-HSA-6806506) PSMA2 [secretory granule lumen] (R-HSA-6803329)	0.527	4
UniProt:P49720 PSMB3	2	PSMB3 [cytosol] (R-HSA-68747) PSMB3 [nucleoplasm] (R-HSA-174341)	0.527	3

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