Reactome | PSMG2 [cytosol]

PSMG2 [cytosol]

Stable Identifier

R-HSA-9908053

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Proteasome assembly chaperone 2, PSMG2_HUMAN, PAC2, Yeast Pba2 ortholog

Locations in the PathwayBrowser for interactor UniProt:Q9BQB4 SOST

Expand all

External Reference Information

External Reference

UniProt:Q969U7 PSMG2

Gene Names

PSMG2, HCCA3, PAC2, TNFSF5IP1

Chain

chain:1-264

Reference Genes

BioGPS Gene:56984 PSMG2

COSMIC (genes):PSMG2 PSMG2

CTD Gene:56984 PSMG2

dbSNP Gene:56984 PSMG2

ENSEMBL:ENSG00000128789 PSMG2

HGNC:24929 PSMG2

KEGG:hsa:56984 PSMG2

Monarch:56984 PSMG2

NCBI Gene:56984 PSMG2

OMIM:609702 PSMG2

UCSC:Q969U7 PSMG2

Reference Transcript

Other Identifiers

11718507_a_at

16851104

16851108

218467_PM_at

218467_at

3655406

3779683

3779685

3779686

3779687

3779688

3779690

3779693

3779694

3779695

3779696

3779697

3779698

3779700

3779701

3779703

3779704

3779705

3779706

3779707

3779708

3779709

3779710

3779711

3779712

3779713

3779714

3779715

56984

64113_at

80187_r_at

8020241

A_14_P113466

A_14_P127660

A_23_P118909

A_24_P399362

A_33_P3357653

GE54607

GO:0005515

GO:0005634

GO:0005829

GO:0007094

GO:0043066

GO:0043226

GO:0043248

GO:0051131

GO:0051726

GO:0060090

GO:0065003

GO:0101031

HMNXSV003043750

HMNXSV003045655

ILMN_2088410

PH_hs_0024404

PH_hs_0035884

TC18001006.hg

TC18001007.hg

g9910421_3p_at

g9910421_3p_s_at

p33479

p7915

Participates

as an input of

PSMG1 binds PSMG2 (Homo sapiens)

as a component of

PSMG1:PSMG2 [cytosol] (Homo sapiens)

Inferred To

PSMG2 [cytosol] (Bos taurus)

PSMG2 [cytosol] (Canis familiaris)

PSMG2 [cytosol] (Gallus gallus)

PSMG2 [cytosol] (Sus scrofa)

Psmg2 [cytosol] (Mus musculus)

Psmg2 [cytosol] (Rattus norvegicus)

psmg2 [cytosol] (Danio rerio)

psmg2 [cytosol] (Xenopus tropicalis)

ADD66 [cytosol] (Saccharomyces cerevisiae)

psmG2 [cytosol] (Dictyostelium discoideum)

Dmel\CG12321 [cytosol] (Drosophila melanogaster)

Ghost homologue of PSMG2 [cytosol] (Caenorhabditis elegans)

Ghost homologue of PSMG2 [cytosol] (Plasmodium falciparum)

Ghost homologue of PSMG2 [cytosol] (Schizosaccharomyces pombe)

Cross References

RefSeq

NP_064617.2, NP_671692.1

ENSEMBL

ENST00000699164, ENSP00000514171, ENSP00000325919, ENST00000585331, ENSP00000476763, ENST00000317615, ENSG00000128789

OpenTargets

ENSG00000128789

GeneCards

PSMG2

HPA

ENSG00000128789-PSMG2

PRO

Q969U7

Pharos - Targets

Q969U7

GlyGen

Q969U7

PDB

8QYM, 8QYS, 8TM3, 8TM4, 8QZ9, 8TM5, 8QYN, 8QYL, 8TM6, 8QYJ

Interactors (30)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9Y244 POMP	1	POMP [cytosol] (R-HSA-9908067)	0.848	8
UniProt:O95456 PSMG1	1	PSMG1 [cytosol] (R-HSA-9908050)	0.847	12
UniProt:P28065 PSMB9	3	PSMB9 [cytosol] (R-HSA-68765) pro-PSMB9 [cytosol] (R-HSA-9908136) PSMB9(1-20) [cytosol] (R-HSA-9908132)	0.725	6
UniProt:Q99436 PSMB7	7	PSMB7 [cytosol] (R-HSA-68759) PSMB7 [nucleoplasm] (R-HSA-174331) pro-PSMB7 [cytosol] (R-HSA-9908145) PSMB7(1-43) [cytosol] (R-HSA-9908129) PSMB7 [ficolin-1-rich granule lumen] (R-HSA-6803312) PSMB7 [extracellular region] (R-HSA-6806449) PSMB7 [secretory granule lumen] (R-HSA-6803279)	0.725	5
UniProt:Q9BT73 PSMG3	1	PSMG3 [cytosol] (R-HSA-9908033)	0.725	6
UniProt:Q5JS54 PSMG4	1	PSMG4 [cytosol] (R-HSA-9908036)	0.725	5
UniProt:Q15323 KRT31	1	KRT31 [cytosol] (R-HSA-6809616)	0.718	6
UniProt:P20618 PSMB1	7	PSMB1 [cytosol] (R-HSA-68738) PSMB1 [nucleoplasm] (R-HSA-174347) pro-PSMB1 [cytosol] (R-HSA-9908139) PSMB1(1-28) [cytosol] (R-HSA-9908143) PSMB1 [ficolin-1-rich granule lumen] (R-HSA-6803340) PSMB1 [extracellular region] (R-HSA-6806477) PSMB1 [secretory granule lumen] (R-HSA-6803287)	0.643	4
UniProt:Q92530 PSMF1	1	PSMF1 [cytosol] (R-HSA-68818)	0.643	4
UniProt:Q06323 PSME1	1	PSME1 [cytosol] (R-HSA-68812)	0.643	3
UniProt:P28066 PSMA5	5	PSMA5 [cytosol] (R-HSA-68732) PSMA5 [nucleoplasm] (R-HSA-174340) PSMA5 [ficolin-1-rich granule lumen] (R-HSA-6803328) PSMA5 [extracellular region] (R-HSA-6806459) PSMA5 [secretory granule lumen] (R-HSA-6803316)	0.643	5
UniProt:Q9NS85 CAH10			0.643	3
UniProt:Q9Y3I1 FBXO7	1	FBXO7 [cytosol] (R-HSA-8862627)	0.643	3
UniProt:P25786 PSMA1	2	PSMA1 [cytosol] (R-HSA-68724) PSMA1 [nucleoplasm] (R-HSA-174333)	0.569	7
UniProt:Q7Z3S9 NOTCH2NLA	3	NOTCH2NLA [extracellular region] (R-HSA-9908935) NOTCH2NLA(1-?) [extracellular region] (R-HSA-9911493) NOTCH2NLA(?-236) [extracellular region] (R-HSA-9911490)	0.556	3
UniProt:P15884 TCF4	1	TCF4 [nucleoplasm] (R-HSA-445672)	0.556	3
UniProt:Q96FE5 LINGO1	1	LINGO1 [plasma membrane] (R-HSA-3006563)	0.527	2
UniProt:P25787 PSMA2	5	PSMA2 [cytosol] (R-HSA-68726) PSMA2 [nucleoplasm] (R-HSA-174345) PSMA2 [ficolin-1-rich granule lumen] (R-HSA-6803285) PSMA2 [extracellular region] (R-HSA-6806506) PSMA2 [secretory granule lumen] (R-HSA-6803329)	0.527	4
UniProt:P49721 PSMB2	2	PSMB2 [cytosol] (R-HSA-68744) PSMB2 [nucleoplasm] (R-HSA-174335)	0.527	3
UniProt:Q9BQB4 SOST	1	SOST [extracellular region] (R-HSA-3769322)	0.527	2
UniProt:P49720 PSMB3	2	PSMB3 [cytosol] (R-HSA-68747) PSMB3 [nucleoplasm] (R-HSA-174341)	0.527	4
UniProt:O14818 PSMA7	2	PSMA7 [cytosol] (R-HSA-68736) PSMA7 [nucleoplasm] (R-HSA-174351)	0.527	3
UniProt:P25789 PSMA4	2	PSMA4 [cytosol] (R-HSA-68730) PSMA4 [nucleoplasm] (R-HSA-174324)	0.527	3
UniProt:P28070 PSMB4	4	PSMB4 [cytosol] (R-HSA-68750) PSMB4 [nucleoplasm] (R-HSA-174343) pro-PSMB4 [cytosol] (R-HSA-9908138) PSMB4(1-45) [cytosol] (R-HSA-9908122)	0.527	3
UniProt:Q9BRX9 WDR83	1	WDR83 [endosome membrane] (R-HSA-5672942)	0.527	2
UniProt:Q9NQ35 NRIP3			0.527	2
UniProt:Q6PJQ5 FOXR2			0.527	2
UniProt:Q8WTP9 XAGE3			0.527	2
UniProt:Q6RVD6 SPAT8			0.527	2
UniProt:Q9BSU1 PHAF1			0.527	2

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