Reactome | POMP [cytosol]

POMP [cytosol]

Stable Identifier

R-HSA-9908067

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Proteasome maturation protein, POMP_HUMAN, UMP1

Locations in the PathwayBrowser for interactor UniProt:O75935 DCTN3

Expand all

External Reference Information

External Reference

UniProt:Q9Y244 POMP

Gene Names

POMP, C13orf12, UMP1, HSPC014, HSPC036, PNAS-110

Chain

chain:1-141

Reference Genes

BioGPS Gene:51371 POMP

COSMIC (genes):POMP POMP

CTD Gene:51371 POMP

dbSNP Gene:51371 POMP

ENSEMBL:ENSG00000132963 POMP

HGNC:20330 POMP

KEGG:hsa:51371 POMP

Monarch:51371 POMP

NCBI Gene:51371 POMP

OMIM:613386 POMP

UCSC:Q9Y244 POMP

Reference Transcript

RefSeq:NM_015932.6 POMP

Other Identifiers

11718762_s_at

11718763_a_at

11757311_x_at

16773583

217769_PM_s_at

217769_s_at

222402_PM_at

222402_at

3483350

3483351

3483352

3483353

3483354

3483356

3483358

3483360

3483363

3483364

3483366

3483369

3483370

3483371

3483372

3483373

3483374

3483375

46940_r_at

51371

56436_at

7968297

A_23_P65254

A_33_P3240263

GE87641

GO:0005515

GO:0005634

GO:0005737

GO:0005783

GO:0005829

GO:0016020

GO:0016607

GO:0043248

GO:0065003

HMNXSV003022572

ILMN_1693287

ILMN_2093810

PH_hs_0023321

TC13000091.hg

g7705428_3p_a_at

Participates

as a component of

as an input of

POMP binds the 20S core particle outer ring (Homo sapiens)

Inferred To

Ghost homologue of POMP [cytosol] (Plasmodium falciparum)

UMP1 [cytosol] (Saccharomyces cerevisiae)

ump1 [cytosol] (Schizosaccharomyces pombe)

Pomp [cytosol] (Drosophila melanogaster)

Pomp [cytosol] (Mus musculus)

Pomp [cytosol] (Rattus norvegicus)

POMP [cytosol] (Bos taurus)

POMP [cytosol] (Caenorhabditis elegans)

POMP [cytosol] (Gallus gallus)

LOC119876205 [cytosol] (Canis familiaris)

pomp [cytosol] (Danio rerio)

pomp [cytosol] (Dictyostelium discoideum)

pomp [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_057016.1

OpenTargets

ENSG00000132963

ENSEMBL

ENST00000380842, ENSP00000370222, ENSG00000132963

HPA

ENSG00000132963-POMP

GeneCards

POMP

PRO

Q9Y244

Pharos - Targets

Q9Y244

PDB

8TM4, 8QZ9, 8TM5, 8QYL, 8QYN, 8TM6, 8QYJ, 8YIY, 8QYS, 8YIX, 8QYM

Interactors (25)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q99436 PSMB7	7	PSMB7 [cytosol] (R-HSA-68759) PSMB7 [nucleoplasm] (R-HSA-174331) pro-PSMB7 [cytosol] (R-HSA-9908145) PSMB7(1-43) [cytosol] (R-HSA-9908129) PSMB7 [secretory granule lumen] (R-HSA-6803279) PSMB7 [extracellular region] (R-HSA-6806449) PSMB7 [ficolin-1-rich granule lumen] (R-HSA-6803312)	0.906	10
UniProt:P49720 PSMB3	2	PSMB3 [cytosol] (R-HSA-68747) PSMB3 [nucleoplasm] (R-HSA-174341)	0.857	9
UniProt:P20618 PSMB1	7	PSMB1 [cytosol] (R-HSA-68738) PSMB1 [nucleoplasm] (R-HSA-174347) pro-PSMB1 [cytosol] (R-HSA-9908139) PSMB1(1-28) [cytosol] (R-HSA-9908143) PSMB1 [secretory granule lumen] (R-HSA-6803287) PSMB1 [extracellular region] (R-HSA-6806477) PSMB1 [ficolin-1-rich granule lumen] (R-HSA-6803340)	0.857	8
UniProt:Q969U7 PSMG2	1	PSMG2 [cytosol] (R-HSA-9908053)	0.848	8
UniProt:P49721 PSMB2	2	PSMB2 [cytosol] (R-HSA-68744) PSMB2 [nucleoplasm] (R-HSA-174335)	0.809	7
UniProt:P25786 PSMA1	2	PSMA1 [cytosol] (R-HSA-68724) PSMA1 [nucleoplasm] (R-HSA-174333)	0.763	9
UniProt:P28074 PSMB5	4	PSMB5 [cytosol] (R-HSA-68753) PSMB5 [nucleoplasm] (R-HSA-174344) pro-PSMB5 [cytosol] (R-HSA-9908135) PSMB5(1-59) [cytosol] (R-HSA-9908134)	0.756	6
UniProt:P28072 PSMB6	4	PSMB6 [cytosol] (R-HSA-68756) PSMB6 [nucleoplasm] (R-HSA-174342) pro-PSMB6 [cytosol] (R-HSA-9908130) PSMB6(1-34) [cytosol] (R-HSA-9908141)	0.756	5
UniProt:P28070 PSMB4	4	PSMB4 [cytosol] (R-HSA-68750) PSMB4 [nucleoplasm] (R-HSA-174343) pro-PSMB4 [cytosol] (R-HSA-9908138) PSMB4(1-45) [cytosol] (R-HSA-9908122)	0.752	6
UniProt:P28066 PSMA5	5	PSMA5 [cytosol] (R-HSA-68732) PSMA5 [nucleoplasm] (R-HSA-174340) PSMA5 [secretory granule lumen] (R-HSA-6803316) PSMA5 [extracellular region] (R-HSA-6806459) PSMA5 [ficolin-1-rich granule lumen] (R-HSA-6803328)	0.744	7
UniProt:P28065 PSMB9	3	PSMB9 [cytosol] (R-HSA-68765) pro-PSMB9 [cytosol] (R-HSA-9908136) PSMB9(1-20) [cytosol] (R-HSA-9908132)	0.738	6
UniProt:O14818 PSMA7	2	PSMA7 [cytosol] (R-HSA-68736) PSMA7 [nucleoplasm] (R-HSA-174351)	0.716	5
UniProt:P25789 PSMA4	2	PSMA4 [cytosol] (R-HSA-68730) PSMA4 [nucleoplasm] (R-HSA-174324)	0.678	4
UniProt:P60900 PSMA6	2	PSMA6 [cytosol] (R-HSA-68734) PSMA6 [nucleoplasm] (R-HSA-174314)	0.669	6
UniProt:O95456 PSMG1	1	PSMG1 [cytosol] (R-HSA-9908050)	0.657	4
UniProt:P25788 PSMA3	2	PSMA3 [cytosol] (R-HSA-68728) PSMA3 [nucleoplasm] (R-HSA-174323)	0.573	3
UniProt:Q5JS54 PSMG4	1	PSMG4 [cytosol] (R-HSA-9908036)	0.564	3
UniProt:Q9BT73 PSMG3	1	PSMG3 [cytosol] (R-HSA-9908033)	0.564	3
UniProt:P25787 PSMA2	5	PSMA2 [cytosol] (R-HSA-68726) PSMA2 [nucleoplasm] (R-HSA-174345) PSMA2 [secretory granule lumen] (R-HSA-6803329) PSMA2 [extracellular region] (R-HSA-6806506) PSMA2 [ficolin-1-rich granule lumen] (R-HSA-6803285)	0.564	5
UniProt:Q15777 MPPD2			0.556	3
UniProt:Q96FE5 LINGO1	1	LINGO1 [plasma membrane] (R-HSA-3006563)	0.527	2
UniProt:Q6PJQ5 FOXR2			0.527	2
UniProt:O75935 DCTN3	1	DCTN3 [cytosol] (R-HSA-380264)	0.527	2
UniProt:Q9BSU1 PHAF1			0.527	2
UniProt:P06929 VE6			0.488	2

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