Reactome | PSMB9(1-20) [cytosol]

PSMB9(1-20) [cytosol]

Stable Identifier

R-HSA-9908132

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Propeptide of immunoproteasome subunit beta-1i

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P28065 PSMB9

Gene Names

PSMB9, LMP2, PSMB6i, RING12

Chain

propeptide:1-20, chain:21-219

Reference Genes

BioGPS Gene:5698 PSMB9

COSMIC (genes):PSMB9 PSMB9

CTD Gene:5698 PSMB9

dbSNP Gene:5698 PSMB9

ENSEMBL:ENSG00000240065 PSMB9

HGNC:9546 PSMB9

KEGG:hsa:5698 PSMB9

Monarch:5698 PSMB9

NCBI Gene:5698 PSMB9

OMIM:177045 PSMB9

UCSC:P28065 PSMB9

Reference Transcript

RefSeq:NM_002800.5 PSMB9

Other Identifiers

11726677_a_at

11735623_a_at

11761758_at

17007307

17028360

17033661

17038644

204279_PM_at

204279_at

2903286

2903298

2903304

2903305

2903306

2903307

2903308

2903309

2903310

2903311

2903312

2903313

2903314

2903315

2903316

2903318

2903319

38287_at

5698

8118571

8178211

8179495

A_14_P109897

A_21_P0010486

A_23_P111000

GE60353

GE728820

GO:0000502

GO:0002376

GO:0004175

GO:0004298

GO:0005515

GO:0005634

GO:0005737

GO:0005829

GO:0005839

GO:0006508

GO:0008233

GO:0016787

GO:0019774

GO:0030163

GO:0043161

GO:0051603

GO:0070062

GO:1990111

HMNXSV003043627

HMNXSV003054514

ILMN_1798233

ILMN_2376108

PH_hs_0013087

PH_hs_0018571

PH_hs_0033030

TC06004082.hg

TC6_apd_hap1000122.hg

TC6_cox_hap2000259.hg

TC6_dbb_hap3000226.hg

TC6_mann_hap4000190.hg

TC6_mcf_hap5000202.hg

TC6_qbl_hap6000215.hg

TC6_ssto_hap7000193.hg

X66401_cds1_at

g4506204_3p_at

p30027

Participates

as an output of

Other forms of this molecule

PSMB9 [cytosol]

pro-PSMB9 [cytosol]

Cross References

RefSeq

NP_002791.1

Guide to Pharmacology - Targets

2409

OpenTargets

ENSG00000240065

ENSEMBL

ENSP00000372721, ENSP00000407810, ENSG00000240508, ENST00000422729, ENSP00000372595, ENSP00000407233, ENSG00000240118, ENST00000453059, ENSP00000363993, ENSG00000243958, ENSG00000242711, ENSG00000240065, ENST00000444284, ENSG00000243067, ENSG00000243594, ENSP00000412027, ENST00000374859, ENSP00000396813, ENST00000383234, ENST00000427870, ENST00000383114, ENST00000434471, ENSG00000239836, ENSP00000393744

ZINC - Substances

PSB9_HUMAN

ZINC target

P28065

PRO

P28065

GlyGen

P28065

PDB

6E5B, 6AVO, 7B12, 7AWE, 9FST

GeneCards

PSMB9

HPA

ENSG00000240065-PSMB9

Pharos - Targets

P28065

ZINC - Predictions - Purchasable

PSB9_HUMAN

Interactors (51)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q99436 PSMB7	7	PSMB7 [cytosol] (R-HSA-68759) PSMB7 [nucleoplasm] (R-HSA-174331) pro-PSMB7 [cytosol] (R-HSA-9908145) PSMB7(1-43) [cytosol] (R-HSA-9908129) PSMB7 [secretory granule lumen] (R-HSA-6803279) PSMB7 [extracellular region] (R-HSA-6806449) PSMB7 [ficolin-1-rich granule lumen] (R-HSA-6803312)	0.845	11
UniProt:Q9Y244 POMP	1	POMP [cytosol] (R-HSA-9908067)	0.738	6
UniProt:P28066 PSMA5	5	PSMA5 [cytosol] (R-HSA-68732) PSMA5 [nucleoplasm] (R-HSA-174340) PSMA5 [secretory granule lumen] (R-HSA-6803316) PSMA5 [extracellular region] (R-HSA-6806459) PSMA5 [ficolin-1-rich granule lumen] (R-HSA-6803328)	0.725	7
UniProt:Q969U7 PSMG2	1	PSMG2 [cytosol] (R-HSA-9908053)	0.725	6
UniProt:P62195 PSMC5	2	PSMC5 [cytosol] (R-HSA-68780) PSMC5 [nucleoplasm] (R-HSA-174312)	0.643	4
UniProt:P49721 PSMB2	2	PSMB2 [cytosol] (R-HSA-68744) PSMB2 [nucleoplasm] (R-HSA-174335)	0.643	5
UniProt:P51665 PSMD7	5	PSMD7 [cytosol] (R-HSA-68806) PSMD7 [nucleoplasm] (R-HSA-174309) PSMD7 [secretory granule lumen] (R-HSA-6801008) PSMD7 [extracellular region] (R-HSA-6806488) PSMD7 [ficolin-1-rich granule lumen] (R-HSA-6800406)	0.643	5
UniProt:P28074 PSMB5	4	PSMB5 [cytosol] (R-HSA-68753) PSMB5 [nucleoplasm] (R-HSA-174344) pro-PSMB5 [cytosol] (R-HSA-9908135) PSMB5(1-59) [cytosol] (R-HSA-9908134)	0.643	5
UniProt:O14818 PSMA7	2	PSMA7 [cytosol] (R-HSA-68736) PSMA7 [nucleoplasm] (R-HSA-174351)	0.643	5
UniProt:Q06323 PSME1	1	PSME1 [cytosol] (R-HSA-68812)	0.643	5
UniProt:Q9BT73 PSMG3	1	PSMG3 [cytosol] (R-HSA-9908033)	0.643	5
UniProt:P60900 PSMA6	2	PSMA6 [cytosol] (R-HSA-68734) PSMA6 [nucleoplasm] (R-HSA-174314)	0.643	5
UniProt:Q9Y3I1 FBXO7	1	FBXO7 [cytosol] (R-HSA-8862627)	0.643	5
UniProt:Q9UL46 PSME2	2	PSME2 [cytosol] (R-HSA-68814) PSME2 [nucleoplasm] (R-HSA-174350)	0.643	5
UniProt:P25787 PSMA2	5	PSMA2 [cytosol] (R-HSA-68726) PSMA2 [nucleoplasm] (R-HSA-174345) PSMA2 [secretory granule lumen] (R-HSA-6803329) PSMA2 [extracellular region] (R-HSA-6806506) PSMA2 [ficolin-1-rich granule lumen] (R-HSA-6803285)	0.643	6
UniProt:P20618 PSMB1	7	PSMB1 [cytosol] (R-HSA-68738) PSMB1 [nucleoplasm] (R-HSA-174347) pro-PSMB1 [cytosol] (R-HSA-9908139) PSMB1(1-28) [cytosol] (R-HSA-9908143) PSMB1 [secretory granule lumen] (R-HSA-6803287) PSMB1 [extracellular region] (R-HSA-6806477) PSMB1 [ficolin-1-rich granule lumen] (R-HSA-6803340)	0.643	5
UniProt:P49720 PSMB3	2	PSMB3 [cytosol] (R-HSA-68747) PSMB3 [nucleoplasm] (R-HSA-174341)	0.643	6
UniProt:Q14657 LAGE3	1	LAGE3 [nucleoplasm] (R-HSA-6784525)	0.601	4
UniProt:Q9Y6Q9 NCOA3	2	NCOA3 [nucleoplasm] (R-HSA-442488) p-S857 NCOA3 [nucleoplasm] (R-HSA-5687005)	0.581	3
UniProt:Q9Y3R0 GRIP1	2	GRIP1 [plasma membrane] (R-HSA-416638) GRIP1 [cytosol] (R-HSA-416633)	0.581	3
UniProt:Q15788 NCOA1	3	NCOA1 [nucleoplasm] (R-HSA-442496) NCOA1 (868-1441) [nucleoplasm] (R-HSA-5603230) monoSUMO1-K732,K774-NCOA1 [nucleoplasm] (R-HSA-4085291)	0.581	3
UniProt:Q24JT5 Q24JT5			0.556	3
UniProt:Q96D03 DDT4L			0.556	3
UniProt:P28070 PSMB4	4	PSMB4 [cytosol] (R-HSA-68750) PSMB4 [nucleoplasm] (R-HSA-174343) pro-PSMB4 [cytosol] (R-HSA-9908138) PSMB4(1-45) [cytosol] (R-HSA-9908122)	0.527	4
UniProt:Q9GZU8 PIP30			0.527	4
UniProt:P17980 PSMC3	5	PSMC3 [cytosol] (R-HSA-68774) PSMC3 [nucleoplasm] (R-HSA-174313) PSMC3 [secretory granule lumen] (R-HSA-6800917) PSMC3 [extracellular region] (R-HSA-6806496) PSMC3 [ficolin-1-rich granule lumen] (R-HSA-6800429)	0.527	4
UniProt:O00487 PSMD14	5	PSMD14 [cytosol] (R-HSA-68722) PSMD14 [nucleoplasm] (R-HSA-174329) PSMD14 [secretory granule lumen] (R-HSA-6800926) PSMD14 [extracellular region] (R-HSA-6806511) PSMD14 [ficolin-1-rich granule lumen] (R-HSA-6800419)	0.527	3
UniProt:P28062 PSMB8	4	PSMB8 [cytosol] (R-HSA-68762) pro-PSMB8 [cytosol] (R-HSA-9908127) PSMB8(1-72) [cytosol] (R-HSA-9908131) PSMB8 [nucleoplasm] (R-HSA-174336)	0.527	2
UniProt:P25786 PSMA1	2	PSMA1 [cytosol] (R-HSA-68724) PSMA1 [nucleoplasm] (R-HSA-174333)	0.527	5
UniProt:P62333 PSMC6	2	PSMC6 [cytosol] (R-HSA-68783) PSMC6 [nucleoplasm] (R-HSA-174319)	0.527	4
UniProt:P48556 PSMD8	2	PSMD8 [cytosol] (R-HSA-68808) PSMD8 [nucleoplasm] (R-HSA-174318)	0.527	2
UniProt:O43242 PSMD3	5	PSMD3 [cytosol] (R-HSA-68798) PSMD3 [nucleoplasm] (R-HSA-174328) PSMD3 [secretory granule lumen] (R-HSA-6800873) PSMD3 [extracellular region] (R-HSA-6806443) PSMD3 [ficolin-1-rich granule lumen] (R-HSA-6800408)	0.527	4
UniProt:O95456 PSMG1	1	PSMG1 [cytosol] (R-HSA-9908050)	0.527	4
UniProt:Q9P0P0 RNF181	1	RNF181 [cytoplasm] (R-HSA-8939317)	0.527	3
UniProt:P55036 PSMD4	1	PSMD4 [cytosol] (R-HSA-68800)	0.527	3
UniProt:O00231 PSMD11	5	PSMD11 [cytosol] (R-HSA-68790) PSMD11 [nucleoplasm] (R-HSA-174327) PSMD11 [secretory granule lumen] (R-HSA-6800943) PSMD11 [extracellular region] (R-HSA-6806441) PSMD11 [ficolin-1-rich granule lumen] (R-HSA-6800436)	0.527	4
UniProt:P35998 PSMC2	5	PSMC2 [cytosol] (R-HSA-68771) PSMC2 [nucleoplasm] (R-HSA-174332) PSMC2 [secretory granule lumen] (R-HSA-6800994) PSMC2 [extracellular region] (R-HSA-6806472) PSMC2 [ficolin-1-rich granule lumen] (R-HSA-6800421)	0.527	4
UniProt:Q92530 PSMF1	1	PSMF1 [cytosol] (R-HSA-68818)	0.527	4
UniProt:P61289 PSME3	1	PSME3 [cytosol] (R-HSA-68816)	0.527	4
UniProt:Q5JS54 PSMG4	1	PSMG4 [cytosol] (R-HSA-9908036)	0.527	4
UniProt:O00232 PSMD12	5	PSMD12 [cytosol] (R-HSA-68792) PSMD12 [nucleoplasm] (R-HSA-174339) PSMD12 [secretory granule lumen] (R-HSA-6800934) PSMD12 [extracellular region] (R-HSA-6806480) PSMD12 [ficolin-1-rich granule lumen] (R-HSA-6800416)	0.527	4
UniProt:Q13200 PSMD2	5	PSMD2 [cytosol] (R-HSA-68796) PSMD2 [nucleoplasm] (R-HSA-174311) PSMD2 [secretory granule lumen] (R-HSA-6800919) PSMD2 [extracellular region] (R-HSA-6806479) PSMD2 [ficolin-1-rich granule lumen] (R-HSA-6800435)	0.527	4
UniProt:Q9NX31 OSER1			0.527	2
UniProt:P62191 PSMC1	2	PSMC1 [cytosol] (R-HSA-68768) PSMC1 [nucleoplasm] (R-HSA-174338)	0.527	3
UniProt:P06732 CKM	1	CKM [cytosol] (R-HSA-200350)	0.527	2
UniProt:Q14997 PSME4	1	PSME4 [cytosol] (R-HSA-947606)	0.527	4
UniProt:Q15008 PSMD6	5	PSMD6 [cytosol] (R-HSA-68804) PSMD6 [nucleoplasm] (R-HSA-174316) PSMD6 [secretory granule lumen] (R-HSA-6801036) PSMD6 [extracellular region] (R-HSA-6806486) PSMD6 [ficolin-1-rich granule lumen] (R-HSA-6800440)	0.527	4
UniProt:P25789 PSMA4	2	PSMA4 [cytosol] (R-HSA-68730) PSMA4 [nucleoplasm] (R-HSA-174324)	0.527	4
UniProt:P25788 PSMA3	2	PSMA3 [cytosol] (R-HSA-68728) PSMA3 [nucleoplasm] (R-HSA-174323)	0.527	4
UniProt:Q9WMX2-PRO_0000037551			0.508	2
UniProt:Q9WMX2-PRO_0000037548			0.508	2

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