Reactome | SGCB [endoplasmic reticulum membrane]

SGCB [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-9913185

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Beta-sarcoglycan, SGCB_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q08AM2 Q08AM2

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External Reference Information

External Reference

UniProt:Q16585 SGCB

Gene Names

SGCB

Chain

chain:1-318

Reference Genes

BioGPS Gene:6443 SGCB

COSMIC (genes):SGCB SGCB

CTD Gene:6443 SGCB

dbSNP Gene:6443 SGCB

ENSEMBL:ENSG00000163069 SGCB

HGNC:10806 SGCB

Monarch:6443 SGCB

NCBI Gene:6443 SGCB

OMIM:600900 SGCB

UCSC:Q16585 SGCB

Reference Transcript

RefSeq:NM_000232.4 SGCB

Other Identifiers

11723226_at

11723227_at

11723228_s_at

16975918

205120_PM_s_at

205120_s_at

205121_PM_at

205121_at

226112_PM_at

226112_at

228584_PM_at

228584_at

2768964

2768980

2768982

2768983

2768984

2768985

2768986

2768987

2768989

2768990

2768991

2768992

2768993

2768994

37223_at

52863_at

63294_at

6443

78662_at

8100318

A_23_P251104

A_33_P3357843

GE59072

GO:0005515

GO:0005737

GO:0005856

GO:0005886

GO:0007517

GO:0009749

GO:0010467

GO:0016010

GO:0016011

GO:0016012

GO:0016020

GO:0042383

GO:0042593

GO:0043226

GO:0044381

GO:0048856

GO:0055001

GO:0055013

GO:0055085

GO:0097084

HMNXSV003014064

Hs.274368.1.S1_3p_at

Hs.77501.1.A1_3p_at

ILMN_1810324

ILMN_2194467

PH_hs_0033439

TC04001194.hg

U31116_at

g1794188_3p_a_at

g4506912_3p_at

Participates

as an input of

SGCB binds SGCD (Homo sapiens)

as a component of

SGCB:SGCD [endoplasmic reticulum membrane] (Homo sapiens)

Other forms of this molecule

SGCB [Golgi membrane]

SGCB [plasma membrane]

Inferred To

Sgcb [endoplasmic reticulum membrane] (Mus musculus)

Sgcb [endoplasmic reticulum membrane] (Rattus norvegicus)

SGCB [endoplasmic reticulum membrane] (Bos taurus)

SGCB [endoplasmic reticulum membrane] (Canis familiaris)

SGCB [endoplasmic reticulum membrane] (Gallus gallus)

SGCB [endoplasmic reticulum membrane] (Sus scrofa)

sgcb-1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)

sgcb [endoplasmic reticulum membrane] (Danio rerio)

sgcb [endoplasmic reticulum membrane] (Xenopus tropicalis)

Scgbeta [endoplasmic reticulum membrane] (Drosophila melanogaster)

Cross References

ENSEMBL

ENSP00000370839, ENST00000381431

OpenTargets

ENSG00000163069

HPA

ENSG00000163069-SGCB

PRO

Q16585

Pharos - Targets

Q16585

GlyGen

Q16585

Orphanet

SGCB

Interactors (20)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q08AT0 Q08AT0			0.666	4
UniProt:Q96DZ9-2 CMTM5			0.556	3
UniProt:Q9BXN2-6 CLEC7A			0.556	3
UniProt:Q6PL45-2 BRICD5			0.556	3
UniProt:Q99735 MGST2	1	MGST2 [endoplasmic reticulum membrane] (R-HSA-176058)	0.556	3
UniProt:O95236-2 APOL3			0.556	3
UniProt:Q92982 NINJ1			0.556	3
UniProt:Q01453 PMP22	1	PMP22 [plasma membrane] (R-HSA-9615623)	0.556	3
UniProt:Q08426 EHHADH	2	EHHADH [peroxisomal matrix] (R-HSA-400155) EHHADH [cytosol] (R-HSA-9033147)	0.556	3
UniProt:P53801 PTTG			0.556	3
UniProt:P21145 MAL			0.556	3
UniProt:P01375 TNF	5	TNF(1-233) [plasma membrane] (R-HSA-66220) TNF(77-233) [extracellular region] (R-HSA-976821) TNF(1-76) [plasma membrane] (R-HSA-8863120) TNF(1-34) [plasma membrane] (R-HSA-8863367) TNF(52-76) [extracellular region] (R-HSA-8863375)	0.556	3
UniProt:Q9BZL3 SMIM3			0.556	3
UniProt:Q9NWF4 SLC52A1	1	SLC52A1 [plasma membrane] (R-HSA-5216118)	0.556	3
UniProt:P17152 TMEM11	1	TMEM11 [mitochondrial inner membrane] (R-HSA-8949578)	0.556	3
UniProt:Q08AM2 Q08AM2			0.556	3
UniProt:Q8WW62 TMED6			0.527	2
UniProt:Q07001 CHRND	1	CHRND [plasma membrane] (R-HSA-507847)	0.527	3
UniProt:Q96FV3 TSN17			0.527	3
UniProt:Q96GX1 TCTN2	1	TCTN2 [ciliary membrane] (R-HSA-5626661)	0.527	2

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