Reactome | ZMYM2 [nucleoplasm]

ZMYM2 [nucleoplasm]

Stable Identifier

R-HSA-9930820

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser for interactor UniProt:O14978 ZNF263

Expand all

Cell-Cell communication (Homo sapiens)

- Cell junction organization (Homo sapiens)
  - Cell-cell junction organization (Homo sapiens)
    - Adherens junctions interactions (Homo sapiens)
      - Regulation of Homotypic Cell-Cell Adhesion (Homo sapiens)
        
        Regulation of Expression and Function of Type I Classical Cadherins (Homo sapiens)
        
        Regulation of CDH1 Expression and Function (Homo sapiens)
        
        Regulation of CDH1 Gene Transcription (Homo sapiens)
        
        Negative Regulation of CDH1 Gene Transcription (Homo sapiens)
        
        DNTTIP1 recruits KDM1A to CDH1 gene promoter (Homo sapiens)
        
        ZMYM2 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9UBW7 ZMYM2

Gene Names

ZMYM2, FIM, RAMP, ZNF198

Chain

chain:1-1377

Reference Genes

BioGPS Gene:7750 ZMYM2

COSMIC (genes):ZMYM2 ZMYM2

CTD Gene:7750 ZMYM2

dbSNP Gene:7750 ZMYM2

ENSEMBL:ENSG00000121741 ZMYM2

HGNC:12989 ZMYM2

KEGG:hsa:7750 ZMYM2

Monarch:7750 ZMYM2

NCBI Gene:7750 ZMYM2

OMIM:602221 ZMYM2

UCSC:Q9UBW7 ZMYM2

Reference Transcript

Other Identifiers

11739414_a_at

11752025_s_at

11759305_at

11759306_s_at

16772942

202778_PM_s_at

202778_s_at

210281_PM_s_at

210281_s_at

210282_PM_at

210282_at

226512_PM_at

226512_at

240642_PM_at

240642_at

242597_PM_at

242597_at

3480130

3480131

3480132

3480133

3480134

3480135

3480136

3480137

3480138

3480141

3480147

3480148

3480149

3480150

3480153

3480154

3480155

3480156

3480157

3480158

3480159

3480160

3480161

3480162

3480163

3480164

3480165

3480166

3480167

3480168

3480171

3480172

3480173

3480174

3480175

3480176

3480177

3480179

3480182

3480184

3480185

3480186

3480187

3480188

3480189

3480190

3480194

3480196

3480197

3480199

3480201

3480202

3480203

3480204

3480206

3480243

3480244

3480246

3504069

3504082

41436_at

45184_at

48606_at

53216_at

62170_at

67358_at

7750

7967900

83358_at

85956_at

A_14_P137536

A_23_P99405

A_24_P237757

GE495605

GE55255

GO:0005515

GO:0005634

GO:0005829

GO:0006355

GO:0008270

GO:0016605

GO:0031624

GO:0045892

GO:0046872

HMNXSV003026538

HMNXSV003041916

HMNXSV003057218

Hs.26490.0.A1_3p_at

Hs.26490.1.A1_3p_at

Hs.41167.0.A1_3p_at

ILMN_1661636

ILMN_2403823

PH_hs_0029730

TC13000021.hg

TC13000927.hg

g12052767_3p_at

g4508010_3p_a_at

This entity regulates

Positively

DNTTIP1 recruits KDM1A to CDH1 gene promoter (Homo sapiens)

Other forms of this molecule

ZMYM2(1-913)-p-FGFR1(429-822) fusion [cytosol]

ZMYM2(1-913)-FGFR1(429-822) fusion [cytosol]

ZMYM2(1-1059)-p-4Y-FLT3(594-993) fusion [cytosol]

ZMYM2(1-1057)-p-5Y-FLT3(586-993) fusion [cytosol]

ZMYM2(1-1059)-FLT3(594-993) fusion [cytosol]

ZMYM2(1-1057)-FLT3(586-993) fusion [cytosol]

Inferred To

Zmym2 [nucleoplasm] (Mus musculus)

Zmym2 [nucleoplasm] (Rattus norvegicus)

ZMYM2 [nucleoplasm] (Bos taurus)

ZMYM2 [nucleoplasm] (Canis familiaris)

ZMYM2 [nucleoplasm] (Gallus gallus)

ZMYM2 [nucleoplasm] (Sus scrofa)

woc [nucleoplasm] (Drosophila melanogaster)

Cross References

RefSeq

NP_001340086.1, XP_005266577.1, XP_047286546.1, XP_016876218.1, NP_003444.1, XP_047286547.1, NP_932072.1, NP_001177893.1, XP_047286544.1, XP_011533526.1, NP_001177894.1, XP_047286545.1, XP_054230903.1, XP_054230904.1, NP_001340093.1, XP_054230905.1, NP_001340091.1, XP_054230906.1, NP_001340088.1

OpenTargets

ENSG00000121741

ENSEMBL

ENST00000382871, ENSP00000479904, ENST00000382874, ENSP00000372327, ENSP00000372324, ENSG00000121741, ENST00000610343

HPA

ENSG00000121741-ZMYM2

GeneCards

ZMYM2

PRO

Q9UBW7

Pharos - Targets

Q9UBW7

GlyGen

Q9UBW7

Interactors (22)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13547 HDAC1	2	HDAC1 [nucleoplasm] (R-HSA-205021) monoSUMO1-K444,K476-HDAC1 [nucleoplasm] (R-HSA-4616030)	0.837	7
UniProt:Q92769 HDAC2	2	HDAC2 [nucleoplasm] (R-HSA-205135) monoSUMO1-K462-HDAC2 [nucleoplasm] (R-HSA-4615958)	0.788	5
UniProt:Q9BUG6 ZSA5A			0.725	5
UniProt:Q8N5I2 ARRD1			0.725	4
UniProt:P63167 DYNLL1	6	DYNLL1 [cytosol] (R-HSA-387105) DYNLL1 [plasma membrane] (R-HSA-54017) DYNLL1 [ficolin-1-rich granule membrane] (R-HSA-6801518) DYNLL1 [tertiary granule membrane] (R-HSA-6801482) DYNLL1 [cilium] (R-HSA-5624863) DYNLL1 [ciliary tip] (R-HSA-5625335)	0.725	4
UniProt:Q96FJ2 DYNLL2	4	DYNLL2 [cytosol] (R-HSA-2029024) DYNLL2 [plasma membrane] (R-HSA-140527) DYNLL2 [cilium] (R-HSA-5624865) DYNLL2 [ciliary tip] (R-HSA-5625337)	0.643	3
UniProt:O95125 ZNF202	1	ZNF202 [nucleoplasm] (R-HSA-975010)	0.643	3
UniProt:Q9UHL9 GT2D1			0.581	5
UniProt:Q9UKT9 IKZF3			0.556	3
UniProt:P22234 PAICS	1	PAICS [cytosol] (R-HSA-62502)	0.556	3
UniProt:Q96IK5 GMCL1			0.556	3
UniProt:Q8N831 TSYL6			0.527	2
UniProt:O14978 ZNF263	1	ZNF263 [nucleoplasm] (R-HSA-1027393)	0.527	3
UniProt:Q16822 PCK2	1	PCK2 [mitochondrial matrix] (R-HSA-372815)	0.527	3
UniProt:Q5VZL5 ZMYM4			0.527	2
UniProt:Q16518 RPE65	1	RPE65 [plasma membrane] (R-HSA-74853)	0.527	2
UniProt:P48431 SOX2	1	SOX2 [nucleoplasm] (R-HSA-452271)	0.527	2
UniProt:Q9UDY6 TRIM10	1	TRIM10 [cytosol] (R-HSA-5624341)	0.527	2
UniProt:Q15198 PGFRL			0.527	2
UniProt:P23246 SFPQ	3	SFPQ [nucleoplasm] (R-HSA-3900138) p-Y-SFPQ [nucleoplasm] (R-HSA-8849461) SFPQ [cytosol] (R-HSA-9635505)	0.524	4
UniProt:P26599 PTBP1	1	PTBP1 [nucleoplasm] (R-HSA-71923)	0.524	2
UniProt:Q83D60 Q83D60			0.488	2

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