Reactome | BCL11B [nucleoplasm]

BCL11B [nucleoplasm]

Stable Identifier

R-HSA-9933971

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

B-cell lymphoma/leukemia 11B, BC11B_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9C0K0 BCL11B

Gene Names

BCL11B, CTIP2, RIT1

Chain

chain:1-894

Reference Genes

BioGPS Gene:64919 BCL11B

COSMIC (genes):BCL11B BCL11B

COSMIC (genes):RIT1 BCL11B

CTD Gene:64919 BCL11B

dbSNP Gene:64919 BCL11B

ENSEMBL:ENSG00000127152 BCL11B

HGNC:13222 BCL11B

KEGG:hsa:64919 BCL11B

Monarch:64919 BCL11B

NCBI Gene:64919 BCL11B

OMIM:606558 BCL11B

UCSC:Q9C0K0 BCL11B

Reference Transcript

Other Identifiers

11733620_a_at

16796590

219528_PM_s_at

219528_s_at

222895_PM_s_at

222895_s_at

224310_PM_s_at

224310_s_at

3579115

3579116

3579117

3579118

3579119

3579120

3579121

3579122

3579123

3579146

3579147

3579163

3579173

3579174

3579175

3579200

44390_at

54401_at

64919

7981242

83823_at

A_23_P205738

A_33_P3358392

GE56909

GO:0000978

GO:0001228

GO:0002376

GO:0003334

GO:0003382

GO:0003677

GO:0003700

GO:0005515

GO:0005634

GO:0006310

GO:0006351

GO:0006355

GO:0006366

GO:0006915

GO:0007409

GO:0008285

GO:0009791

GO:0010468

GO:0010837

GO:0012501

GO:0016514

GO:0019216

GO:0021773

GO:0021902

GO:0021953

GO:0030154

GO:0031077

GO:0033077

GO:0033153

GO:0035701

GO:0042475

GO:0043005

GO:0043226

GO:0043368

GO:0043565

GO:0043588

GO:0045664

GO:0045944

GO:0046632

GO:0046872

GO:0048538

GO:0048856

GO:0048870

GO:0070231

GO:0070233

GO:0070242

GO:0070244

GO:0071678

GO:0097535

GO:0140110

GO:1990837

HMNXSV003030218

Hs.57987.0.S1_3p_a_at

ILMN_1665761

ILMN_1667885

PH_hs_0003725

TC14001497.hg

g12597634_3p_a_at

g13094150_3p_a_at

Participates

as a member of

BCL11A, BCL11B [nucleoplasm] (Homo sapiens)

Inferred To

Bcl11b [nucleoplasm] (Mus musculus)

Bcl11b [nucleoplasm] (Rattus norvegicus)

Cph [nucleoplasm] (Drosophila melanogaster)

bcl-11 [nucleoplasm] (Caenorhabditis elegans)

BCL11B [nucleoplasm] (Bos taurus)

BCL11B [nucleoplasm] (Canis familiaris)

BCL11B [nucleoplasm] (Gallus gallus)

BCL11B [nucleoplasm] (Sus scrofa)

Cross References

ENSEMBL

ENST00000345514, ENSG00000127152, ENSP00000349723, ENSP00000280435, ENST00000357195

OpenTargets

ENSG00000127152

GeneCards

BCL11B

HPA

ENSG00000127152-BCL11B

PRO

Q9C0K0

Pharos - Targets

Q9C0K0

GlyGen

Q9C0K0

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q92769 HDAC2	2	HDAC2 [nucleoplasm] (R-HSA-205135) monoSUMO1-K462-HDAC2 [nucleoplasm] (R-HSA-4615958)	0.695	5
UniProt:Q13547 HDAC1	2	HDAC1 [nucleoplasm] (R-HSA-205021) monoSUMO1-K444,K476-HDAC1 [nucleoplasm] (R-HSA-4616030)	0.695	5
UniProt:O43463 SUV39H1	1	SUV39H1 [nucleoplasm] (R-HSA-427517)	0.556	3
UniProt:P46531 NOTCH1	20	NOTCH1 L1678P S2 cleavage fragment [extracellular region] (R-HSA-2730745) NOTCH1 I1680N S2 cleavage fragment [extracellular region] (R-HSA-2730744) NOTCH1 I1718T S2 cleavage fragment [extracellular region] (R-HSA-2730757) NOTCH1 A1701P S2 cleavage fragment [plasma membrane] (R-HSA-2730742) NOTCH1 V1676D S2 cleavage fragment [extracellular region] (R-HSA-2730755) NOTCH1 I1680N Transmembrane Fragment [plasma membrane] (R-HSA-2684869) NOTCH1 I1718T Transmembrane Fragment [plasma membrane] (R-HSA-2684881) NOTCH1 I1616T Extracellular Fragment [extracellular region] (R-HSA-2684866) NOTCH1 L1596H Extracellular Fragment [extracellular region] (R-HSA-2684853) NOTCH1 L1678P Transmembrane Fragment [plasma membrane] (R-HSA-1485591) NOTCH1 A1701P Transmembrane Fragment [plasma membrane] (R-HSA-1485585) NOTCH1 I1616N Extracellular Fragment [extracellular region] (R-HSA-2684862) NOTCH1 L1593P Extracellular Fragment [extracellular region] (R-HSA-1485584) NOTCH1 R1598P Extracellular Fragment [extracellular region] (R-HSA-1485592) NOTCH1 V1576E Extracellular Fragment [extracellular region] (R-HSA-2684852) NOTCH1 V1676D Transmembrane Fragment [plasma membrane] (R-HSA-2684874) NOTCH1 F1592S Extracellular Fragment [extracellular region] (R-HSA-2684847) NOTCH1 L1574Q Extracellular Fragment [extracellular region] (R-HSA-2691203) p-NICD1 Q2440* [nucleoplasm] (R-HSA-2902207) p-NICD1 Q2395* [nucleoplasm] (R-HSA-2902205)	0.462	2

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