Reactome | DXO [nucleoplasm]

DXO [nucleoplasm]

Stable Identifier

R-HSA-9935314

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

fullName evidence="12"Decapping and exoribonuclease protein, DXO_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O77932 DXO

Gene Names

DXO, DOM3L, DOM3Z, NG6

Chain

chain:1-396

Reference Genes

BioGPS Gene:1797 DXO

COSMIC (genes):DXO DXO

CTD Gene:1797 DXO

dbSNP Gene:1797 DXO

ENSEMBL:ENSG00000204348 DXO

HGNC:2992 DXO

KEGG:hsa:1797 DXO

Monarch:1797 DXO

NCBI Gene:1797 DXO

OMIM:605996 DXO

UCSC:O77932 DXO

Reference Transcript

Other Identifiers

11732379_a_at

11756558_s_at

17017602

17029456

17032242

17036949

17039692

17042197

1797

204522_PM_at

204522_at

215982_PM_s_at

215982_s_at

2949590

2949591

2949592

2949593

2949594

2949595

2949596

2949597

2949598

2949599

2949600

2949601

2949602

2949604

2949605

2949606

2949607

2949608

2949609

2949610

2949611

2949613

38157_PM_at

38157_at

8125220

8178699

8179926

A_32_P181020

GE54548

GO:0000166

GO:0000287

GO:0000956

GO:0003723

GO:0003729

GO:0003824

GO:0004518

GO:0004527

GO:0005515

GO:0005634

GO:0005654

GO:0005829

GO:0005886

GO:0006402

GO:0008409

GO:0016071

GO:0016787

GO:0034353

GO:0046872

GO:0050779

GO:0071028

GO:0090304

GO:0110152

GO:0110155

GO:0140098

HMNXSV003018311

HMNXSV003023580

Hs.153299.1.S1_3p_s_at

ILMN_1726990

PH_hs_0009220

TC06001553.hg

TC06003595.hg

TC6_cox_hap2000181.hg

TC6_dbb_hap3000170.hg

TC6_mcf_hap5000156.hg

TC6_qbl_hap6000171.hg

TC6_ssto_hap7000149.hg

Participates

as a component of

DXO:Mg2+ [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_054186990.1, XP_054210391.1, XP_006715068.1, XP_047274218.1, NP_005501.2, XP_054185719.1, XP_054186754.1, XP_054187256.1

OpenTargets

ENSG00000204348

ENSEMBL

ENSG00000224313, ENSG00000225682, ENST00000454430, ENST00000399937, ENST00000453742, ENST00000383330, ENSG00000206346, ENSG00000204348, ENST00000399936, ENSP00000415675, ENST00000375349, ENST00000419797, ENSP00000395262, ENSG00000236765, ENSP00000391123, ENSP00000364498, ENSP00000410404, ENSP00000382818, ENSP00000391349, ENSP00000400173, ENSP00000372820, ENSP00000382819, ENST00000414092, ENSP00000337759, ENST00000446967, ENST00000426498, ENSP00000364505, ENST00000432110, ENST00000443250, ENST00000458308, ENST00000337523, ENSP00000411380, ENSP00000401315, ENSP00000391532, ENST00000375356, ENST00000427690, ENSP00000394167, ENSG00000234798, ENSP00000413860, ENST00000439989, ENSP00000406143, ENST00000427627

GeneCards

DXO

HPA

ENSG00000204348-DXO

PRO

O77932

Pharos - Targets

O77932

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P16284 PECAM1	5	PECAM1 [plasma membrane] (R-HSA-114686) p-Y663,Y686-PECAM1(27-?) [plasma membrane] (R-HSA-210007) PECAM1 [secretory granule membrane] (R-HSA-6804778) p-Y713-PECAM1 [plasma membrane] (R-HSA-9860772) PECAM1 [platelet alpha granule membrane] (R-HSA-61489)	0.556	3
UniProt:P08670 VIM	12	Vimentin [lysosomal lumen] (R-HSA-9659977) Vimentin [cytosol] (R-HSA-9646687) Vimentin [microtubule organizing center] (R-HSA-9657898) Vimentin [late endosome lumen] (R-HSA-9660019) VIM [cytosol] (R-HSA-201600) VIM(2-259) [cytosol] (R-HSA-350323) VIM(260-466) [cytosol] (R-HSA-350314) VIM(2-429) [cytosol] (R-HSA-350317) VIM(430-466) [cytosol] (R-HSA-350316) VIM(86-466) [cytosol] (R-HSA-350294) VIM(2-85) [cytosol] (R-HSA-350264) p39-VIM [cytosol] (R-HSA-9948102)	0.556	3
UniProt:P04792 HSPB1	3	HSPB1 [cytosol] (R-HSA-450563) p-S15,S78,S82-HSP27 [cytosol] (R-HSA-5218697) p-S78,S82 HSPB1 [cytosol] (R-HSA-5687009)	0.556	3
UniProt:P10809 HSPD1	6	HSPD1 [mitochondrial inner membrane] (R-HSA-1299455) HSPD1 [mitochondrial matrix] (R-HSA-1299448) HSPD1(1-573) [mitochondrial inner membrane] (R-HSA-1299442) HSPD1(1-26) [mitochondrial matrix] (R-HSA-8986171) HSPD1(1-573) [mitochondrial intermembrane space] (R-HSA-1267963) HSPD1(1-573) [cytosol] (R-HSA-1267989)	0.556	3
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:P54652 HSPA2	2	HSPA2 [cytosol] (R-HSA-3371408) HSPA2 [nucleoplasm] (R-HSA-912480)	0.488	2

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