Reactome | DHRSX [endoplasmic reticulum membrane]

DHRSX [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-9937274

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

fullName evidence="12"Polyprenol dehydrogenase ecNumber evidence="8"1.3.-.-, DHRSX_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q9Y5Q0 FADS3

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External Reference Information

External Reference

UniProt:Q8N5I4 DHRSX

Gene Names

DHRSX, CXorf11, DHRS5X, SDR46C1, SDR7C6, UNQ6508/PRO21433

Chain

initiator methionine:, chain:2-330

Reference Genes

BioGPS Gene:207063 DHRSX

COSMIC (genes):DHRSX DHRSX

CTD Gene:207063 DHRSX

dbSNP Gene:207063 DHRSX

ENSEMBL:ENSG00000169084 DHRSX

HGNC:18399 DHRSX

KEGG:hsa:207063 DHRSX

Monarch:207063 DHRSX

NCBI Gene:207063 DHRSX

OMIM:301034 DHRSX

OMIM:400049 DHRSX

UCSC:Q8N5I4 DHRSX

Reference Transcript

RefSeq:NM_145177.2 DHRSX

Other Identifiers

11729180_at

11729181_at

17108745

17116748

207063

225503_PM_at

225503_at

238053_PM_at

238053_at

3997542

3997544

3997574

3997575

3997576

4033344

4033364

4033365

47913_at

54578_at

65130_at

72464_at

A_24_P378987

A_33_P3334908

GE56677

GO:0003824

GO:0005515

GO:0005576

GO:0010508

GO:0016491

HMNXSV003011145

Hs.11779.0.S1_3p_at

Hs.16129.0.A1_3p_at

ILMN_1704139

PH_hs_0030993

PH_hs_0034921

Inferred To

Dhrsx [endoplasmic reticulum membrane] (Rattus norvegicus)

DHRSX [endoplasmic reticulum membrane] (Caenorhabditis elegans)

DHRSX [endoplasmic reticulum membrane] (Canis familiaris)

DHRSX [endoplasmic reticulum membrane] (Danio rerio)

DHRSX [endoplasmic reticulum membrane] (Sus scrofa)

LOC102159510 [endoplasmic reticulum membrane] (Sus scrofa)

Homologues of DHRSX [endoplasmic reticulum membrane] (Sus scrofa)

dhrsx [endoplasmic reticulum membrane] (Xenopus tropicalis)

Dmel\CG11200 [endoplasmic reticulum membrane] (Drosophila melanogaster)

Cross References

ENSEMBL

ENSP00000334113, ENST00000334651, ENSP00000518604, ENSG00000169084, ENSG00000292338, ENST00000711204

OpenTargets

ENSG00000169084

GeneCards

DHRSX

HPA

ENSG00000169084-DHRSX

PRO

Q8N5I4

Pharos - Targets

Q8N5I4

Interactors (18)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O96006 ZBED1	1	ZBED1 [nucleoplasm] (R-HSA-8956376)	0.589	3
UniProt:Q96DZ9-2 CMTM5			0.556	3
IntAct:EBI-22326698 CCSB ORF ID			0.556	3
UniProt:Q96MV8 ZDH15			0.556	3
UniProt:Q8NBQ5 HSD17B11	1	HSD17B11 [cytosol] (R-HSA-5693370)	0.556	3
UniProt:O15173 PGRMC2	4	PGRMC2 [nuclear envelope] (R-HSA-9707674) PGRMC2 [nucleoplasm] (R-HSA-9707859) PGRMC2 [endoplasmic reticulum membrane] (R-HSA-9714349) PGRMC2 [endosome membrane] (R-HSA-9715090)	0.556	3
UniProt:Q96GQ5 RUSF1			0.556	3
UniProt:Q96MV1 TLCD4			0.556	3
UniProt:Q96AN5 TM143			0.556	3
UniProt:P02654 APOC1	1	APOC1 [extracellular region] (R-HSA-8855541)	0.556	3
UniProt:Q86VR2 RETR3			0.556	3
UniProt:Q9UHD4 CIDEB			0.556	3
UniProt:Q13520 AQP6	1	AQP6 [transport vesicle membrane] (R-HSA-431741)	0.556	3
UniProt:Q9Y5Q0 FADS3			0.556	3
UniProt:Q9NUH8 TM14B			0.556	3
UniProt:Q12797-6 ASPH			0.556	3
UniProt:P57054 PIGP	1	PIGP(26-158) [endoplasmic reticulum membrane] (R-HSA-162761)	0.556	3
UniProt:Q8N661 TMEM86B	1	TMEM86B [endoplasmic reticulum membrane] (R-HSA-8874443)	0.556	3

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