Reactome | Xyl-GlcA-Xyl-RboP-RboP-GalNAc-GlcNAc-Man6P-DAG1 [Golgi lumen]

O-mannosyl-L-threonine (3-O-(α-D-Xyl-(1→3)-β-D-GlcA-(1→4)-β-D-Xyl-(1→4)-Rib-ol-P-Rib-ol-P-3-β-D-GalNAc-(1→3)-β-D-GlcNAc-(1→4)-O-6-P-α-D-Man)-L-threonine residue) at 367

Coordinate

367

Modification

3-O-(α-D-Xyl-(1→3)-β-D-GlcA-(1→4)-β-D-Xyl-(1→4)-Rib-ol-P-Rib-ol-P-3-β-D-GalNAc-(1→3)-β-D-GlcNAc-(1→4)-O-6-P-α-D-Man)-L-threonine residue

PsiMod Name

O-mannosyl-L-threonine

PsiMod Definition

a protein modification that effectively forms a O3-mannosylthreonine

Name

O-mannosyl-L-threonine (N-acetyl-beta-D-glucosaminyl-(1-2)-alpha-D-mannosyl group) at 423

Coordinate

423

Modification

N-acetyl-beta-D-glucosaminyl-(1-2)-alpha-D-mannosyl group

PsiMod Name

O-mannosyl-L-threonine

PsiMod Definition

a protein modification that effectively forms a O3-mannosylthreonine

Name

O-mannosyl-L-threonine (N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-D-glucosaminyl-1,2)-beta-D-mannosyl group) at 481

Coordinate

481

Modification

N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-D-glucosaminyl-1,2)-beta-D-mannosyl group

PsiMod Name

O-mannosyl-L-threonine

PsiMod Definition

a protein modification that effectively forms a O3-mannosylthreonine

Cross References

RefSeq

XP_047303514.1, NP_001171114.2, XP_047303516.1, NP_001171108.2, NP_001171112.2, XP_047303534.1, XP_047303495.1, NP_001171106.2, XP_047303508.1, XP_047303506.1, NP_001159400.3, XP_047303529.1, XP_047303523.1, XP_047303532.1, XP_047303522.1, XP_047303519.1, NP_001171111.2, XP_047303515.1, XP_047303510.1, XP_047303526.1, NP_001171105.2, XP_047303512.1, NP_001171109.2, XP_047303505.1, XP_047303503.1, XP_047303524.1, NP_001171107.2, XP_047303498.1, XP_047303535.1, XP_047303521.1, XP_047303518.1, XP_047303525.1, XP_047303502.1, XP_047303504.1, XP_047303527.1, NP_001171110.2, XP_047303497.1, NP_001171113.2, XP_047303500.1, XP_047303499.1, XP_047303511.1, XP_047303530.1, XP_047303520.1, NP_001171115.2, XP_047303501.1, XP_047303517.1, XP_047303513.1, XP_047303531.1, XP_047303507.1, XP_047303509.1, XP_047303533.1, NP_004384.5, XP_047303496.1, XP_047303528.1

OpenTargets

ENSG00000173402

ENSEMBL

ENST00000418588, ENST00000452317, ENSP00000401805, ENST00000469139, ENST00000308775, ENST00000673708, ENSP00000410145, ENST00000496474, ENSP00000312435, ENST00000435508, ENST00000431960, ENST00000430636, ENSP00000401382, ENST00000466701, ENSP00000412067, ENST00000428779, ENST00000697271, ENSP00000415321, ENSP00000388833, ENSP00000405859, ENSG00000173402, ENSP00000501140, ENSP00000513216, ENSP00000501165, ENSP00000513217, ENSP00000513218, ENST00000452060, ENSP00000387859, ENST00000421560

GeneCards

DAG1

HPA

ENSG00000173402-DAG1

PRO

Q14118

Pharos - Targets

Q14118

GlyGen

Q14118

Orphanet

DAG1

PDB

2MK7, 6JJY, 7E9L, 7E9K, 5GGP, 1EG4, 5LLK

Interactors (16)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q14118 DAG1	20	DAG1(654-895) [plasma membrane] (R-HSA-2328154) DAG1(30-653) [extracellular region] (R-HSA-2328152) DAG1(30-653) [cytosol] (R-HSA-5615641) DAG1(30-653) [endoplasmic reticulum lumen] (R-HSA-8931890) Man-DAG1 [endoplasmic reticulum lumen] (R-HSA-5615647) DAG1 [endoplasmic reticulum membrane] (R-HSA-9913254) DAG1(654-895) [endoplasmic reticulum membrane] (R-HSA-9913257) Core M1,3-DAG1 [Golgi lumen] (R-HSA-5617087) Core M1,2,3-DAG1 [Golgi lumen] (R-HSA-8932424) Core M3-DAG1 [Golgi lumen] (R-HSA-9940750) GalNAc-GlcNAc-Man6P-DAG1 [endoplasmic reticulum lumen] (R-HSA-8931659) GalNAc-GlcNAc-Man-DAG1 [endoplasmic reticulum lumen] (R-HSA-8931656) GlcNAc-Man-DAG1 [endoplasmic reticulum lumen] (R-HSA-8931673) RboP-RboP-GalNAc-GlcNAc-Man6P-DAG1 [Golgi lumen] (R-HSA-9940668) Xyl-RboP-RboP-GalNAc-GlcNAc-Man6P-DAG1 [Golgi lumen] (R-HSA-9940723) RboP-GalNAc-GlcNAc-Man6P-DAG1 [Golgi lumen] (R-HSA-9940763) GlcA-Xyl-RboP-RboP-GalNAc-GlcNAc-Man6P-DAG1 [Golgi lumen] (R-HSA-9940727) Xyl-GlcA-Xyl-RboP-RboP-GalNAc-GlcNAc-Man6P-DAG1 [Golgi lumen] (R-HSA-9940697) Matriglycan-DAG1 [Golgi lumen] (R-HSA-9940706) 3S-Matriglycan-DAG1 [Golgi lumen] (R-HSA-9940731)	0.558	2
UniProt:P46939 UTRN	1	UTRN [cytosol] (R-HSA-5216039)	0.527	2
UniProt:P33151 CDH5	2	p-S665-VE-cadherin [plasma membrane] (R-HSA-5357435) VE-cadherin [plasma membrane] (R-HSA-418992)	0.527	2
UniProt:O00214 LEG8			0.527	2
UniProt:Q9NU53 GINM1			0.527	2
UniProt:Q9Y5G4 PCDG9			0.527	2
UniProt:Q8WXA8 HTR3C	1	HTR3C [plasma membrane] (R-HSA-975312)	0.527	2
UniProt:O95302 FKBP9	1	FKBP9 [cytosol] (R-HSA-391306)	0.527	2
UniProt:Q9Y5F2 PCDBB			0.527	2
UniProt:P01375 TNF	5	TNF(1-233) [plasma membrane] (R-HSA-66220) TNF(77-233) [extracellular region] (R-HSA-976821) TNF(1-76) [plasma membrane] (R-HSA-8863120) TNF(1-34) [plasma membrane] (R-HSA-8863367) TNF(52-76) [extracellular region] (R-HSA-8863375)	0.527	2
UniProt:Q96GX1 TCTN2	1	TCTN2 [ciliary membrane] (R-HSA-5626661)	0.527	2
UniProt:P20036 HLA-DPA1	9	HLA class II histocompatibility antigen, DP alpha chain precursor [plasma membrane] (R-HSA-197586) HLA class II histocompatibility antigen, DP alpha chain precursor [lysosomal membrane] (R-HSA-2130639) HLA class II histocompatibility antigen, DP alpha chain precursor [endocytic vesicle membrane] (R-HSA-2130435) HLA class II histocompatibility antigen, DP alpha chain precursor [clathrin-coated endocytic vesicle membrane] (R-HSA-2130485) HLA class II histocompatibility antigen, DP alpha chain precursor [transport vesicle membrane] (R-HSA-2130648) HLA class II histocompatibility antigen, DP alpha chain precursor [trans-Golgi network membrane] (R-HSA-2130337) HLA class II histocompatibility antigen, DP alpha chain precursor [Golgi membrane] (R-HSA-2214387) HLA class II histocompatibility antigen, DP alpha chain precursor [ER to Golgi transport vesicle membrane] (R-HSA-2130739) HLA class II histocompatibility antigen, DP alpha chain precursor [lumenal side of endoplasmic reticulum membrane] (R-HSA-2130667)	0.527	2
UniProt:Q14627 IL13RA2	1	IL13RA2 [extracellular region] (R-HSA-449666)	0.527	2
UniProt:P32971 TNFSF8	1	TNFSF8 [plasma membrane] (R-HSA-5667148)	0.527	3
UniProt:Q9UK22 FBXO2	1	FBXO2 [cytosol] (R-HSA-976044)	0.527	2
UniProt:P21926 CD9	4	CD9 [plasma membrane] (R-HSA-51717) CD9 [endocytic vesicle membrane] (R-HSA-5334774) CD9 [clathrin-coated endocytic vesicle membrane] (R-HSA-5334779) CD9 [platelet alpha granule membrane] (R-HSA-114585)	0.462	2

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