JMJD1C demethylates H3K9 mono- and di-methylation

Stable Identifier
R-HSA-997263
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
JMJD1C demethylates H3K9 mono- and di-methylation
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

JMJD1C specifically demethylates histone H3K9 mono- and di-methylation, thereby mediating transcriptional activation.

Literature References
PubMed ID Title Journal Year
20530532 Regulation of mouse steroidogenesis by WHISTLE and JMJD1C through histone methylation balance

Kook, H, Kook, H, Seol, JE, Bhak, YY, Nam, KI, Kim, DW, Cho, IH, Lee, SE, Kim, SM, Kim, JR, Seo, SB, Choe, NW, Kim, JY

Nucleic Acids Res 2010
Participants
Input
Output
Participates
as an event of
Catalyst Activity

histone H3-methyl-lysine-9 demethylase activity of JMJD1C [nucleoplasm]

Physical Entity
JMJD1C [nucleoplasm] (Homo sapiens)
Activity
histone H3-methyl-lysine-9 demethylase activity (GO:0032454)
Orthologous Events
JMJD1C demethylates H3K9 mono- and di-methylation (Bos taurus)
JMJD1C demethylates H3K9 mono- and di-methylation (Canis familiaris)
JMJD1C demethylates H3K9 mono- and di-methylation (Danio rerio)
JMJD1C demethylates H3K9 mono- and di-methylation (Drosophila melanogaster)
JMJD1C demethylates H3K9 mono- and di-methylation (Gallus gallus)
JMJD1C demethylates H3K9 mono- and di-methylation (Mus musculus)
JMJD1C demethylates H3K9 mono- and di-methylation (Plasmodium falciparum)
JMJD1C demethylates H3K9 mono- and di-methylation (Rattus norvegicus)
JMJD1C demethylates H3K9 mono- and di-methylation (Sus scrofa)
JMJD1C demethylates H3K9 mono- and di-methylation (Xenopus tropicalis)
Authored
Ouwehand, WH  (2010-11-12)
Reviewed
Akkerman, JW  (2010-10-29)
Created
Jupe, S  (2010-11-08)
Cite Us!