Reactome | Dephosphorylation of JAK1 by SHP1

Dephosphorylation of JAK1 by SHP1

Stable Identifier

R-HSA-997314

Type

Reaction [transition]

Species

Homo sapiens

Compartment

cytosol, plasma membrane

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SHP1 directly associates with and dephosphorylates JAK1/2.

Literature References

PubMed ID	Title	Journal	Year
18508557	Protein tyrosine phosphatases in the JAK/STAT pathway Xu, D, Qu, CK	Front Biosci	2008
8943354	Direct association with and dephosphorylation of Jak2 kinase by the SH2-domain-containing protein tyrosine phosphatase SHP-1 Jiao, H, Platanias, LC, Yi, T, Yang, W, Tabrizi, M, Berrada, K	Mol Cell Biol	1996