Reactome | Turkey MYLK phosphorylates MRLCs of the non-muscle myosin II complex

Turkey MYLK phosphorylates MRLCs of the non-muscle myosin II complex

Stable Identifier

R-MGA-5672766

Type

Reaction [transition]

Species

Meleagris gallopavo

Compartment

cytosol

ReviewStatus

5/5

General

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Turkey MYLK phosphorylates MRLCs of the non-muscle myosin II complex

Phosphorylation of myosin regulatory light chains (MRLC) by myosin light chain kinase (MYLK, MLCK) was demonstrated using proteins isolated from turkey gizzard (Ikebe and Hartshorne 1985, Ikebe 1986).

Literature References

PubMed ID	Title	Journal	Year
3079756	Identification, phosphorylation, and dephosphorylation of a second site for myosin light chain kinase on the 20,000-dalton light chain of smooth muscle myosin Elzinga, M, Ikebe, M, Hartshorne, DJ	J Biol Chem	1986
3839510	Phosphorylation of smooth muscle myosin at two distinct sites by myosin light chain kinase Hartshorne, DJ, Ikebe, M	J. Biol. Chem.	1985

Participants

Input

Output

Catalyst Activity

protein serine/threonine kinase activity of MYLK:Ca2+:CALM1 [cytosol]

Physical Entity

MYLK:Ca2+:CALM1 [cytosol] (Meleagris gallopavo)

Activity

protein serine/threonine kinase activity (GO:0004674)

Orthologous Events

MYLK (MLCK) phosphorylates MRLCs of the non-muscle myosin II complex (Homo sapiens)

Authored

Orlic-Milacic, M (2015-02-02)

Rivero Crespo, F (2014-12-26)

Created

Orlic-Milacic, M (2015-02-06)

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