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What is Reactome ?
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Ub [cytosol]
Stable Identifier
R-MMU-113595
Type
Set [DefinedSet]
Species
Mus musculus
Compartment
cytosol
Synonyms
ubiquitin
Locations in the PathwayBrowser
Expand all
Autophagy (Mus musculus)
Macroautophagy (Mus musculus)
Selective autophagy (Mus musculus)
Aggrephagy (Mus musculus)
Aggresome dissociates from dynein and microtubule (Mus musculus)
Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6 [cytosol] (Mus musculus)
PolyUb-Misfolded Proteins:HDAC6 [cytosol] (Mus musculus)
PolyUb-Misfolded Proteins [cytosol] (Mus musculus)
Ub-misfolded nascent CFTR [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Mus musculus)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Mus musculus)
PolyUb-Misfolded Proteins:HDAC6:Dynein complex [cytosol] (Mus musculus)
PolyUb-Misfolded Proteins:HDAC6 [cytosol] (Mus musculus)
PolyUb-Misfolded Proteins [cytosol] (Mus musculus)
Ub-misfolded nascent CFTR [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Mus musculus)
Misfolded proteins:PRKN:UBE2N:UBE2V1:Ub [cytosol] (Mus musculus)
Ub:UBE2N:UBE2V1:PRKN [cytosol] (Mus musculus)
Ub:UBE2N:UBE2V1 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:UBE2N:UBE2V1:PRKN [cytosol] (Mus musculus)
Ub:UBE2N:UBE2V1 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Parkin binds Ub:UBE2N:UBE2V1 (Mus musculus)
Ub:UBE2N:UBE2V1 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:UBE2N:UBE2V1:PRKN [cytosol] (Mus musculus)
Ub:UBE2N:UBE2V1 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Parkin transfers Ub to misfolded proteins (Mus musculus)
Misfolded proteins:PRKN:UBE2N:UBE2V1:Ub [cytosol] (Mus musculus)
Ub:UBE2N:UBE2V1:PRKN [cytosol] (Mus musculus)
Ub:UBE2N:UBE2V1 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:Misfolded proteins:PRKN:UBE2N:UBE2V1 [cytosol] (Mus musculus)
Ub-Misfolded Proteins [cytosol] (Mus musculus)
Ub-misfolded nascent CFTR [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
PolyUb-Misfolded Proteins:HDAC6 bind dynein motor (Mus musculus)
PolyUb-Misfolded Proteins:HDAC6 [cytosol] (Mus musculus)
PolyUb-Misfolded Proteins [cytosol] (Mus musculus)
Ub-misfolded nascent CFTR [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
PolyUb-Misfolded Proteins:HDAC6:Dynein complex [cytosol] (Mus musculus)
PolyUb-Misfolded Proteins:HDAC6 [cytosol] (Mus musculus)
PolyUb-Misfolded Proteins [cytosol] (Mus musculus)
Ub-misfolded nascent CFTR [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
PolyUb-Misfolded proteins bind vimentin to form aggresome (Mus musculus)
Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Mus musculus)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Mus musculus)
PolyUb-Misfolded Proteins:HDAC6:Dynein complex [cytosol] (Mus musculus)
PolyUb-Misfolded Proteins:HDAC6 [cytosol] (Mus musculus)
PolyUb-Misfolded Proteins [cytosol] (Mus musculus)
Ub-misfolded nascent CFTR [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Mus musculus)
PolyUb-Misfolded Proteins:HDAC6:Dynein complex [cytosol] (Mus musculus)
PolyUb-Misfolded Proteins:HDAC6 [cytosol] (Mus musculus)
PolyUb-Misfolded Proteins [cytosol] (Mus musculus)
Ub-misfolded nascent CFTR [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 (Mus musculus)
PolyUb-Misfolded Proteins [cytosol] (Mus musculus)
Ub-misfolded nascent CFTR [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
PolyUb:Misfolded proteins:PRKN:UBE2N:UBE2V1 [cytosol] (Mus musculus)
PolyUb-Misfolded Proteins [cytosol] (Mus musculus)
Ub-misfolded nascent CFTR [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Mus musculus)
PolyUb:Misfolded proteins:PRKN:UBE2N:UBE2V1 [cytosol] (Mus musculus)
PolyUb-Misfolded Proteins [cytosol] (Mus musculus)
Ub-misfolded nascent CFTR [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:Misfolded proteins:PRKN:UBE2N:UBE2V1 [cytosol] (Mus musculus)
Ub-Misfolded Proteins [cytosol] (Mus musculus)
Ub-misfolded nascent CFTR [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Mitophagy (Mus musculus)
PINK1-PRKN Mediated Mitophagy (Mus musculus)
PRKN ubiquitinates MOM substrates (Mus musculus)
Ub:Ub-UBE2D2,UBE2D3,UBE2N:UBE2V1,UBE2L3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Pexophagy (Mus musculus)
ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (Mus musculus)
Ub [cytosol] (Mus musculus)
USP30 deubiquitinates ATM dimer:Ub-p-PEX5 (Mus musculus)
Ub [cytosol] (Mus musculus)
Cell Cycle (Mus musculus)
Cell Cycle Checkpoints (Mus musculus)
G1/S DNA Damage Checkpoints (Mus musculus)
p53-Dependent G1/S DNA damage checkpoint (Mus musculus)
p53-Dependent G1 DNA Damage Response (Mus musculus)
Stabilization of p53 (Mus musculus)
Autodegradation of the E3 ubiquitin ligase COP1 (Mus musculus)
Autoubiquitination of phospho-COP1(Ser-387 ) (Mus musculus)
Ub [cytosol] (Mus musculus)
ubiquitinated phospho-COP1(ser-387) [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Proteasome mediated degradation of COP1 (Mus musculus)
Ub [cytosol] (Mus musculus)
ubiquitinated phospho-COP1(ser-387) [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
p53-Independent G1/S DNA damage checkpoint (Mus musculus)
p53-Independent DNA Damage Response (Mus musculus)
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A (Mus musculus)
Proteolytic degradation of ubiquitinated-Cdc25A (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub-p-S124-CDC25A [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
G2/M Checkpoints (Mus musculus)
GTSE1 facilitates proteasome-mediated degradation of TP53 (Mus musculus)
Ub [cytosol] (Mus musculus)
Cell Cycle, Mitotic (Mus musculus)
M Phase (Mus musculus)
Mitotic Metaphase and Anaphase (Mus musculus)
Mitotic Anaphase (Mus musculus)
Separation of Sister Chromatids (Mus musculus)
Degradation of multiubiquitinated Securin (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Mus musculus)
Ub [cytosol] (Mus musculus)
Mitotic G2-G2/M phases (Mus musculus)
G2/M Transition (Mus musculus)
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis (Mus musculus)
Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Mus musculus)
Ub [cytosol] (Mus musculus)
Proteasome-mediated degradation of PolyUb-FBXL7 (Mus musculus)
Ub [cytosol] (Mus musculus)
SCF-FBXL18 ubiquitinates FBXL7 (Mus musculus)
Ub [cytosol] (Mus musculus)
SCF-FBXL7 ubiquitinates AURKA (Mus musculus)
Ub [cytosol] (Mus musculus)
Regulation of PLK1 Activity at G2/M Transition (Mus musculus)
SCF-beta-TrCp1/2 ubiquitinates phosphorylated BORA (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub-p-S252,S497,T501-BORA [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
The role of GTSE1 in G2/M progression after G2 checkpoint (Mus musculus)
GTSE1 facilitates proteasome-mediated degradation of TP53 (Mus musculus)
Ub [cytosol] (Mus musculus)
Regulation of mitotic cell cycle (Mus musculus)
APC/C-mediated degradation of cell cycle proteins (Mus musculus)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Mus musculus)
Degradation of multiubiquitinated cell cycle proteins (Mus musculus)
Ub [cytosol] (Mus musculus)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Mus musculus)
Ub [cytosol] (Mus musculus)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Mus musculus)
APC/C:Cdc20 mediated degradation of mitotic proteins (Mus musculus)
APC/C:Cdc20 mediated degradation of Cyclin B (Mus musculus)
Degradation of multiubiquitinated Cyclin B (Mus musculus)
Ub [cytosol] (Mus musculus)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Mus musculus)
Ub [cytosol] (Mus musculus)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
APC/C:Cdc20 mediated degradation of Securin (Mus musculus)
Degradation of multiubiquitinated Securin (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Mus musculus)
Ub [cytosol] (Mus musculus)
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Mus musculus)
APC-Cdc20 mediated degradation of Nek2A (Mus musculus)
Degradation of multiubiquitinated Nek2A (Mus musculus)
Multiubiquitinated Nek2A [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Multiubiquitination of Nek2A (Mus musculus)
Multiubiquitinated Nek2A [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Mus musculus)
Degradation multiubiquitinated Cyclin A (Mus musculus)
Ub [cytosol] (Mus musculus)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Mus musculus)
Ub [cytosol] (Mus musculus)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Regulation of APC/C activators between G1/S and early anaphase (Mus musculus)
SCF-beta-TrCP mediated degradation of Emi1 (Mus musculus)
Ubiquitination of Emi1 by SCF-beta-TrCP (Mus musculus)
SCF-associated multiubiquitinated Emi1complexes [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
S Phase (Mus musculus)
Synthesis of DNA (Mus musculus)
Switching of origins to a post-replicative state (Mus musculus)
CDK-mediated phosphorylation and removal of Cdc6 (Mus musculus)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Mus musculus)
Ub [cytosol] (Mus musculus)
ubiquitinated Cdc6 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitinated Cdc6 is degraded by the proteasome (Mus musculus)
Ub [cytosol] (Mus musculus)
ubiquitinated Cdc6 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Orc1 removal from chromatin (Mus musculus)
Ubiquitinated Orc1 is degraded by the proteasome (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitin-dependent degradation of Cyclin D (Mus musculus)
Proteasome mediated degradation of Cyclin D1 (Mus musculus)
Ub [cytosol] (Mus musculus)
multi-ubiquitinated phospho-(T286) Cyclin D1 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular response to chemical stress (Mus musculus)
KEAP1-NFE2L2 pathway (Mus musculus)
26S proteasome degrades Ub-NFE2L2 (Mus musculus)
Ub [cytosol] (Mus musculus)
CUL3:RBX1 ubiquitinates KEAP1 (Mus musculus)
Ub [cytosol] (Mus musculus)
KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer (Mus musculus)
Ub [cytosol] (Mus musculus)
KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 (Mus musculus)
Ub [cytosol] (Mus musculus)
MUL1 ubiquitinates UBXN7 (Mus musculus)
Ub [cytosol] (Mus musculus)
TRIM21 ubiquitinates SQSTM1 (Mus musculus)
Ub [cytosol] (Mus musculus)
ub UBXN7 is degraded by the 26S proteasome (Mus musculus)
Ub [cytosol] (Mus musculus)
Cellular response to hypoxia (Mus musculus)
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Mus musculus)
Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha (Mus musculus)
UBE2D1,2,3:Ubiquitin [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1:LIMD1,AJUBA,WTIF:PHD2,3 [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Proteasome proteolyzes ub-HIF-alpha (Mus musculus)
Ub [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha:VCB (with or without LIMD1) [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1:LIMD1,AJUBA,WTIF:PHD2,3 [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol (Mus musculus)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
DNA Replication (Mus musculus)
Synthesis of DNA (Mus musculus)
Switching of origins to a post-replicative state (Mus musculus)
CDK-mediated phosphorylation and removal of Cdc6 (Mus musculus)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Mus musculus)
Ub [cytosol] (Mus musculus)
ubiquitinated Cdc6 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitinated Cdc6 is degraded by the proteasome (Mus musculus)
Ub [cytosol] (Mus musculus)
ubiquitinated Cdc6 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Orc1 removal from chromatin (Mus musculus)
Ubiquitinated Orc1 is degraded by the proteasome (Mus musculus)
Ub [cytosol] (Mus musculus)
Developmental Biology (Mus musculus)
Nervous system development (Mus musculus)
Axon guidance (Mus musculus)
Signaling by ROBO receptors (Mus musculus)
Regulation of expression of SLITs and ROBOs (Mus musculus)
USP33 deubiquitinates ROBO1 (Mus musculus)
Ub [cytosol] (Mus musculus)
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Mus musculus)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Mus musculus)
USP9X (FAM) deubiquitinates SMAD4 (Mus musculus)
Ub [cytosol] (Mus musculus)
Transcriptional regulation by RUNX1 (Mus musculus)
RUNX1 regulates transcription of genes involved in differentiation of HSCs (Mus musculus)
26S proteasome degrades TP73 polyubiquitinated by ITCH (Mus musculus)
Ub [cytosol] (Mus musculus)
ITCH polyubiquitinates TP73 (Mus musculus)
Ub [cytosol] (Mus musculus)
Transcriptional regulation by RUNX2 (Mus musculus)
Regulation of RUNX2 expression and activity (Mus musculus)
STUB1 polyubiquitinates RUNX2 (Mus musculus)
Ub [cytosol] (Mus musculus)
Transcriptional regulation by RUNX3 (Mus musculus)
Regulation of RUNX3 expression and activity (Mus musculus)
Polyubiquitinated RUNX3 is degraded by the proteasome (Mus musculus)
Ub [cytosol] (Mus musculus)
Immune System (Mus musculus)
Adaptive Immune System (Mus musculus)
Class I MHC mediated antigen processing & presentation (Mus musculus)
Antigen processing: Ubiquitination & Proteasome degradation (Mus musculus)
E1 mediated ubiquitin activation (Mus musculus)
E1 bound ubiquitin [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Interaction of E3 with substrate and E2-Ub complex (Mus musculus)
Ag-substrate:E3:E2:Ub [cytosol] (Mus musculus)
Ubiquitin:E2 conjugating enzymes [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitin:E2 conjugating enzymes [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Polyubiquitination of substrate (Mus musculus)
E3:Ub:substrate [cytosol] (Mus musculus)
Ub:substrate [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitin:E2 conjugating enzymes [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Proteasomal cleavage of substrate (Mus musculus)
Ub [cytosol] (Mus musculus)
Transfer of Ub from E2 to substrate and release of E2 (Mus musculus)
Ag-substrate:E3:E2:Ub [cytosol] (Mus musculus)
Ubiquitin:E2 conjugating enzymes [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
E3:Ub:substrate [cytosol] (Mus musculus)
Ub:substrate [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Transfer of ubiquitin from E1 to E2 (Mus musculus)
E1 bound ubiquitin [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitin:E2 conjugating enzymes [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Signaling by the B Cell Receptor (BCR) (Mus musculus)
Downstream signaling events of B Cell Receptor (BCR) (Mus musculus)
Activation of NF-kappaB in B cells (Mus musculus)
SCF-beta-TrCP ubiquitinylates IkB (Mus musculus)
Ub [cytosol] (Mus musculus)
Cytokine Signaling in Immune system (Mus musculus)
FLT3 Signaling (Mus musculus)
Negative regulation of FLT3 (Mus musculus)
Ubiquitination of FLT3 (Mus musculus)
Ub [cytosol] (Mus musculus)
Interferon Signaling (Mus musculus)
Interferon alpha/beta signaling (Mus musculus)
Recruitment of STAT2 to p-IFNAR1 (Mus musculus)
multiubiquitinated STAT2 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Signaling by CSF3 (G-CSF) (Mus musculus)
Inactivation of CSF3 (G-CSF) signaling (Mus musculus)
SOCS1,3 ubiquitinates CSF3R in SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 (Mus musculus)
Ub:UBE2D1,2,3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Signaling by Interleukins (Mus musculus)
Interleukin-1 family signaling (Mus musculus)
Interleukin-1 signaling (Mus musculus)
Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex (Mus musculus)
BTRC:CUL1:RBX1:SKP1:NFKB1:RELA:p-S32,S36-NFKBIA:Ub [cytosol] (Mus musculus)
NFKB1:RELA:p-S32,S36-NFKBIA:Ub [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Mus musculus)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Mus musculus)
Ub [cytosol] (Mus musculus)
SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2 (Mus musculus)
Ub [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Regulation of NF-kappa B signaling (Mus musculus)
TRAF2,6 ubiquitinates NLRC5 (Mus musculus)
Ub [cytosol] (Mus musculus)
USP14 deubiquitinates NLRC5 (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex (Mus musculus)
NFKB1:RELA:p-S32,S36-NFKBIA:Ub [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Interleukin-17 signaling (Mus musculus)
MAP kinase activation (Mus musculus)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Mus musculus)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Mus musculus)
Ub [cytosol] (Mus musculus)
SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2 (Mus musculus)
Ub [cytosol] (Mus musculus)
TNFR2 non-canonical NF-kB pathway (Mus musculus)
NIK-->noncanonical NF-kB signaling (Mus musculus)
26S proteasome processes p-7S-p100:RELB to form p52:RELB (Mus musculus)
Ub [cytosol] (Mus musculus)
Innate Immune System (Mus musculus)
Alpha-protein kinase 1 signaling pathway (Mus musculus)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon ALPK1:ADP-heptose stimulation (Mus musculus)
Ub [cytosol] (Mus musculus)
Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer (Mus musculus)
Ub [cytosol] (Mus musculus)
C-type lectin receptors (CLRs) (Mus musculus)
CLEC7A (Dectin-1) signaling (Mus musculus)
Dectin-1 mediated noncanonical NF-kB signaling (Mus musculus)
26S proteasome processes p-7S-p100:RELB to form p52:RELB (Mus musculus)
Ub [cytosol] (Mus musculus)
Cytosolic sensors of pathogen-associated DNA (Mus musculus)
Regulation of innate immune responses to cytosolic DNA (Mus musculus)
DDX41 ubiquitination by TRIM21 (Mus musculus)
Ub [cytosol] (Mus musculus)
DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3 (Mus musculus)
Ub [cytosol] (Mus musculus)
STING ubiquitination by TRIM32 or TRIM56 (Mus musculus)
Ub [cytosol] (Mus musculus)
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Mus musculus)
Negative regulators of DDX58/IFIH1 signaling (Mus musculus)
CYLD mediated deubiquitination of DDX58 (RIG-I) (Mus musculus)
Ub [cytosol] (Mus musculus)
Toll-like Receptor Cascades (Mus musculus)
Toll Like Receptor 10 (TLR10) Cascade (Mus musculus)
MyD88 cascade initiated on plasma membrane (Mus musculus)
IRAK2 mediated activation of TAK1 complex (Mus musculus)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Mus musculus)
Ub [cytosol] (Mus musculus)
Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 (Mus musculus)
Ub [cytosol] (Mus musculus)
MAP kinase activation (Mus musculus)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Mus musculus)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Mus musculus)
Ub [cytosol] (Mus musculus)
SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2 (Mus musculus)
Ub [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Regulation of NF-kappa B signaling (Mus musculus)
TRAF2,6 ubiquitinates NLRC5 (Mus musculus)
Ub [cytosol] (Mus musculus)
USP14 deubiquitinates NLRC5 (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
Ub [cytosol] (Mus musculus)
Toll Like Receptor 2 (TLR2) Cascade (Mus musculus)
Toll Like Receptor TLR1:TLR2 Cascade (Mus musculus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
IRAK2 mediated activation of TAK1 complex (Mus musculus)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Mus musculus)
Ub [cytosol] (Mus musculus)
Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 (Mus musculus)
Ub [cytosol] (Mus musculus)
MAP kinase activation (Mus musculus)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Mus musculus)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Mus musculus)
Ub [cytosol] (Mus musculus)
SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2 (Mus musculus)
Ub [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Regulation of NF-kappa B signaling (Mus musculus)
TRAF2,6 ubiquitinates NLRC5 (Mus musculus)
Ub [cytosol] (Mus musculus)
USP14 deubiquitinates NLRC5 (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
Ub [cytosol] (Mus musculus)
Toll Like Receptor TLR6:TLR2 Cascade (Mus musculus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
IRAK2 mediated activation of TAK1 complex (Mus musculus)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Mus musculus)
Ub [cytosol] (Mus musculus)
Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 (Mus musculus)
Ub [cytosol] (Mus musculus)
MAP kinase activation (Mus musculus)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Mus musculus)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Mus musculus)
Ub [cytosol] (Mus musculus)
SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2 (Mus musculus)
Ub [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Regulation of NF-kappa B signaling (Mus musculus)
TRAF2,6 ubiquitinates NLRC5 (Mus musculus)
Ub [cytosol] (Mus musculus)
USP14 deubiquitinates NLRC5 (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
Ub [cytosol] (Mus musculus)
Toll Like Receptor 3 (TLR3) Cascade (Mus musculus)
MAP kinase activation (Mus musculus)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Mus musculus)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Mus musculus)
Ub [cytosol] (Mus musculus)
SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2 (Mus musculus)
Ub [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Regulation of NF-kappa B signaling (Mus musculus)
TRAF2,6 ubiquitinates NLRC5 (Mus musculus)
Ub [cytosol] (Mus musculus)
USP14 deubiquitinates NLRC5 (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
Ub [cytosol] (Mus musculus)
Toll Like Receptor 4 (TLR4) Cascade (Mus musculus)
MyD88-independent TLR4 cascade (Mus musculus)
TRIF (TICAM1)-mediated TLR4 signaling (Mus musculus)
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) (Mus musculus)
Auto-ubiquitination of TRAF3 (Mus musculus)
Ub [cytosol] (Mus musculus)
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 (Mus musculus)
IKKε (IKBKE) is ubiquitinated within the activated TLR4 (Mus musculus)
Ub [cytosol] (Mus musculus)
TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 (Mus musculus)
Ub [cytosol] (Mus musculus)
TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TRIF:activated TLR4 (Mus musculus)
Ub [cytosol] (Mus musculus)
IKK complex recruitment mediated by RIP1 (Mus musculus)
K63-linked ubiquitination of RIP1 bound to the activated TLR complex (Mus musculus)
RIP1 ubiqutin ligases [cytosol] (Mus musculus)
c-IAP1:UBE2D [cytosol] (Mus musculus)
UBE2D1,2,3:Ubiquitin [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
c-IAP2:UBE2D [cytosol] (Mus musculus)
UBE2D1,2,3:Ubiquitin [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
MAP kinase activation (Mus musculus)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Mus musculus)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Mus musculus)
Ub [cytosol] (Mus musculus)
SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2 (Mus musculus)
Ub [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Regulation of NF-kappa B signaling (Mus musculus)
TRAF2,6 ubiquitinates NLRC5 (Mus musculus)
Ub [cytosol] (Mus musculus)
USP14 deubiquitinates NLRC5 (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
Ub [cytosol] (Mus musculus)
TRAF6-mediated induction of TAK1 complex within TLR4 complex (Mus musculus)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation (Mus musculus)
Ub [cytosol] (Mus musculus)
Auto ubiquitination of TRAF6 bound to the activated TLR4 complex (Mus musculus)
Ub [cytosol] (Mus musculus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
IRAK2 mediated activation of TAK1 complex (Mus musculus)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Mus musculus)
Ub [cytosol] (Mus musculus)
Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 (Mus musculus)
Ub [cytosol] (Mus musculus)
MAP kinase activation (Mus musculus)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Mus musculus)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Mus musculus)
Ub [cytosol] (Mus musculus)
SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2 (Mus musculus)
Ub [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Regulation of NF-kappa B signaling (Mus musculus)
TRAF2,6 ubiquitinates NLRC5 (Mus musculus)
Ub [cytosol] (Mus musculus)
USP14 deubiquitinates NLRC5 (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
Ub [cytosol] (Mus musculus)
Toll Like Receptor 5 (TLR5) Cascade (Mus musculus)
MyD88 cascade initiated on plasma membrane (Mus musculus)
IRAK2 mediated activation of TAK1 complex (Mus musculus)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Mus musculus)
Ub [cytosol] (Mus musculus)
Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 (Mus musculus)
Ub [cytosol] (Mus musculus)
MAP kinase activation (Mus musculus)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Mus musculus)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Mus musculus)
Ub [cytosol] (Mus musculus)
SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2 (Mus musculus)
Ub [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Regulation of NF-kappa B signaling (Mus musculus)
TRAF2,6 ubiquitinates NLRC5 (Mus musculus)
Ub [cytosol] (Mus musculus)
USP14 deubiquitinates NLRC5 (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
Ub [cytosol] (Mus musculus)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Mus musculus)
MyD88 dependent cascade initiated on endosome (Mus musculus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Mus musculus)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Mus musculus)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation (Mus musculus)
Ub [cytosol] (Mus musculus)
Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane (Mus musculus)
Ub [cytosol] (Mus musculus)
MAP kinase activation (Mus musculus)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Mus musculus)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Mus musculus)
Ub [cytosol] (Mus musculus)
SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2 (Mus musculus)
Ub [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Regulation of NF-kappa B signaling (Mus musculus)
TRAF2,6 ubiquitinates NLRC5 (Mus musculus)
Ub [cytosol] (Mus musculus)
USP14 deubiquitinates NLRC5 (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
Ub [cytosol] (Mus musculus)
Toll Like Receptor 9 (TLR9) Cascade (Mus musculus)
MyD88 dependent cascade initiated on endosome (Mus musculus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Mus musculus)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Mus musculus)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation (Mus musculus)
Ub [cytosol] (Mus musculus)
Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane (Mus musculus)
Ub [cytosol] (Mus musculus)
MAP kinase activation (Mus musculus)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Mus musculus)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Mus musculus)
Ub [cytosol] (Mus musculus)
SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2 (Mus musculus)
Ub [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Regulation of NF-kappa B signaling (Mus musculus)
TRAF2,6 ubiquitinates NLRC5 (Mus musculus)
Ub [cytosol] (Mus musculus)
USP14 deubiquitinates NLRC5 (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
Ub [cytosol] (Mus musculus)
Metabolism (Mus musculus)
Aerobic respiration and respiratory electron transport (Mus musculus)
Pyruvate metabolism (Mus musculus)
Regulation of pyruvate metabolism (Mus musculus)
CTLH E3 ligase ubiquitinates LDHA (Mus musculus)
Ub [cytosol] (Mus musculus)
CTLH E3 ligase ubiquitinates PKM-1 (Mus musculus)
Ub [cytosol] (Mus musculus)
Metabolism of RNA (Mus musculus)
Regulation of mRNA stability by proteins that bind AU-rich elements (Mus musculus)
AUF1 (hnRNP D0) binds and destabilizes mRNA (Mus musculus)
AUF1 (hnRNP D0) is ubiquitinylated (Mus musculus)
Ub [cytosol] (Mus musculus)
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Asparagine N-linked glycosylation (Mus musculus)
N-glycan trimming in the ER and Calnexin/Calreticulin cycle (Mus musculus)
Calnexin/calreticulin cycle (Mus musculus)
ER Quality Control Compartment (ERQC) (Mus musculus)
Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol (Mus musculus)
Ub-unfolded protein:(GlcNAc)2 (Man)9-5 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub-unfolded protein:(GlcNAc)2 (Man)9-5 [endoplasmic reticulum quality control compartment] (Mus musculus)
Ub [cytosol] (Mus musculus)
Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins (Mus musculus)
Ub-unfolded protein:(GlcNAc)2 (Man)9-5 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) (Mus musculus)
Ub-unfolded protein:(GlcNAc)2 (Man)9-5 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Deubiquitination (Mus musculus)
Ovarian tumor domain proteases (Mus musculus)
OTUD7A hydrolyses K11diUb (Mus musculus)
Ub [cytosol] (Mus musculus)
UCH proteinases (Mus musculus)
UCHL1, UCHL3 cleave ubiquitin adducts (Mus musculus)
UCHL1,UCHL3:Ub [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub-specific processing proteases (Mus musculus)
CYLD mediated deubiquitination of DDX58 (RIG-I) (Mus musculus)
Ub [cytosol] (Mus musculus)
USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 (Mus musculus)
Ub [cytosol] (Mus musculus)
USP34 deubiquitinates AXIN1,AXIN2 (Mus musculus)
Ub [cytosol] (Mus musculus)
USP5 cleaves polyubiquitin (Mus musculus)
USP5:Ub [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
USP8 deubiquitinates STAM2:HGS (Mus musculus)
Ub [cytosol] (Mus musculus)
USP9X (FAM) deubiquitinates SMAD4 (Mus musculus)
Ub [cytosol] (Mus musculus)
Neddylation (Mus musculus)
26S proteasome degrades HIFalpha (Mus musculus)
Ub [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:NEDD8-CUL2:RBX1:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
26S proteasome degrades Ub-NFE2L2 (Mus musculus)
Ub [cytosol] (Mus musculus)
KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 (Mus musculus)
Ub [cytosol] (Mus musculus)
MUL1 ubiquitinates UBXN7 (Mus musculus)
Ub [cytosol] (Mus musculus)
VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha (Mus musculus)
UBE2D1,2,3:Ubiquitin [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:NEDD8-CUL2:RBX1:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
ub UBXN7 is degraded by the 26S proteasome (Mus musculus)
Ub [cytosol] (Mus musculus)
Protein ubiquitination (Mus musculus)
E3 ubiquitin ligases ubiquitinate target proteins (Mus musculus)
PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 (Mus musculus)
PEX2:PEX10:PEX12:PEX5S,L:Ub:UBE2D1,2,3:PEX13:PEX14 [peroxisomal membrane] (Mus musculus)
Ub:UBE2D1,2,3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:UBE2D1,2,3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Mus musculus)
PEX2:PEX10:PEX12:PEX5S,L:Ub:UBE2D1,2,3:PEX13:PEX14 [peroxisomal membrane] (Mus musculus)
Ub:UBE2D1,2,3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 [peroxisomal membrane] (Mus musculus)
Ub:PEX5L [peroxisomal membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
RNF144A binds PRKDC and Ubiquitin:UBE2L3 (Mus musculus)
RNF144A:PRKDC:Ub:UBE2L3 [cytosol] (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
RNF144A polyubiquitinates PRKDC (Mus musculus)
RNF144A:PRKDC:Ub:UBE2L3 [cytosol] (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 (Mus musculus)
RNF152:RRAGA:GDP:Ub:UBE2N [lysosomal membrane] (Mus musculus)
Ub:UBE2N [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:UBE2N [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
RNF152 polyubiquitinates RRAGA (Mus musculus)
RNF152:RRAGA:GDP:Ub:UBE2N [lysosomal membrane] (Mus musculus)
Ub:UBE2N [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:UBE2N [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
RNF181 binds BCL10 and Ubiquitin:E2 (Mus musculus)
RNF181:BCL10:Ub:E2 [cytoplasm] (Mus musculus)
Ub:UBE2D1,UBE2D2,UBE2D3, UBE2E1,UBE2N [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:UBE2D1,UBE2D2,UBE2D3, UBE2E1,UBE2N [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
RNF181 polyubiquinates BCL10 (Mus musculus)
RNF181:BCL10:Ub:E2 [cytoplasm] (Mus musculus)
Ub:UBE2D1,UBE2D2,UBE2D3, UBE2E1,UBE2N [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:UBE2D1,UBE2D2,UBE2D3, UBE2E1,UBE2N [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Mus musculus)
UBA1 adenylates ubiquitin in the cytosol (Mus musculus)
Ub [cytosol] (Mus musculus)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Mus musculus)
Ub-Cys632-UBA1 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
UBA1 conjugates ubiquitin to cytosolic E2 enzymes (Mus musculus)
Ub-Cys632-UBA1:ubiquitin adenylate [cytosol] (Mus musculus)
Ub-Cys632-UBA1 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:E2 (UBA1 substrate) [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
UBA6 conjugates ubiquitin to cytosolic E2 enzymes (Mus musculus)
Ub-Cys625-UBA6:ubiquitin adenylate [cytosol] (Mus musculus)
Ub-Cys625-UBA6 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:E2 (UBA6 substrate) [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub-Cys632-UBA1 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub-Cys632-UBA1:ubiquitin adenylate [cytosol] (Mus musculus)
Ub-Cys632-UBA1 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Programmed Cell Death (Mus musculus)
Regulated Necrosis (Mus musculus)
RIPK1-mediated regulated necrosis (Mus musculus)
Regulation of necroptotic cell death (Mus musculus)
ITCH polyubiquitinates MLKL at K50 (Mus musculus)
p-S-RIPK1:p-S-RIPK3:p-T,S-MLKL:ITCH:Ub:UBE2L3 [cytosol] (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
MLKL binds ITCH (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
p-S-RIPK1:p-S-RIPK3:p-T,S-MLKL:ITCH:Ub:UBE2L3 [cytosol] (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
PRKN polyubiquitinates RIPK3 (Mus musculus)
RIPK3:p-S9-PRKN:Ub:UBE2L3 [cytosol] (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
RIPK3 binds p-S9-PRKN (Mus musculus)
RIPK3:p-S9-PRKN:Ub:UBE2L3 [cytosol] (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
STUB1 ubiquitinates RIPK3 at K55, K363 (Mus musculus)
Ub [cytosol] (Mus musculus)
Protein localization (Mus musculus)
Peroxisomal protein import (Mus musculus)
PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol (Mus musculus)
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14:PEX1:PEX6:PEX26:ZFAND6 [peroxisomal membrane] (Mus musculus)
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 [peroxisomal membrane] (Mus musculus)
Ub:PEX5L [peroxisomal membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:PEX5L [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 (Mus musculus)
PEX2:PEX10:PEX12:PEX5L:Ub:UBE2D1,2,3:PEX7:PEX13:PEX14 [peroxisomal membrane] (Mus musculus)
Ub:UBE2D1,2,3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:UBE2D1,2,3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 (Mus musculus)
PEX2:PEX10:PEX12:PEX5S,L:Ub:UBE2D1,2,3:PEX13:PEX14 [peroxisomal membrane] (Mus musculus)
Ub:UBE2D1,2,3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:UBE2D1,2,3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 (Mus musculus)
PEX2:PEX10:PEX12:PEX5L:Ub:UBE2D1,2,3:PEX7:PEX13:PEX14 [peroxisomal membrane] (Mus musculus)
Ub:UBE2D1,2,3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 [peroxisomal membrane] (Mus musculus)
Ub:PEX5L [peroxisomal membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Mus musculus)
PEX2:PEX10:PEX12:PEX5S,L:Ub:UBE2D1,2,3:PEX13:PEX14 [peroxisomal membrane] (Mus musculus)
Ub:UBE2D1,2,3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 [peroxisomal membrane] (Mus musculus)
Ub:PEX5L [peroxisomal membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 (Mus musculus)
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 [peroxisomal membrane] (Mus musculus)
Ub:PEX5L [peroxisomal membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14:PEX1:PEX6:PEX26:ZFAND6 [peroxisomal membrane] (Mus musculus)
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 [peroxisomal membrane] (Mus musculus)
Ub:PEX5L [peroxisomal membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 (Mus musculus)
PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 [peroxisomal membrane] (Mus musculus)
Ub:PEX5L [peroxisomal membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX1:PEX6:PEX26:ZFAND6 [peroxisomal membrane] (Mus musculus)
PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 [peroxisomal membrane] (Mus musculus)
Ub:PEX5L [peroxisomal membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
USP9X binds Ub:PEX5L (Mus musculus)
USP9X:Ub:PEX5L [cytosol] (Mus musculus)
Ub:PEX5L [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:PEX5L [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin (Mus musculus)
USP9X:Ub:PEX5L [cytosol] (Mus musculus)
Ub:PEX5L [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Death Receptor Signaling (Mus musculus)
TNF signaling (Mus musculus)
Regulation of TNFR1 signaling (Mus musculus)
CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex (Mus musculus)
Ub [cytosol] (Mus musculus)
CYLD hydrolyses M1polyUb on RIPK1 within the TNFR1 complex (Mus musculus)
Ub [cytosol] (Mus musculus)
K63polyUb-RIPK1 is deubiquitinated (Mus musculus)
Ub [cytosol] (Mus musculus)
LUBAC ubiquitinates RIPK1 at K627 (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
MIB2 binds CFLAR (Mus musculus)
CFLAR:MIB2:Ub:UBE2D1 [cytosol] (Mus musculus)
Ub:UBE2D1 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:UBE2D1 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
MIB2 binds CYLD (Mus musculus)
MIB2:CYLD:UBE2D2 [cytosol] (Mus musculus)
Ub:UBE2D2 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:UBE2D2 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
MIB2 binds RIPK1 within TNF-α:TNFR1:TRADD:RIPK1:TRAF2 (Mus musculus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2:MIB2:Ub:UBE2D1 [plasma membrane] (Mus musculus)
Ub:UBE2D1 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:UBE2D1 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
MIB2 ubiquitinates CFLAR (Mus musculus)
CFLAR:MIB2:Ub:UBE2D1 [cytosol] (Mus musculus)
Ub:UBE2D1 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
MIB2 ubiquitinates CYLD at K338, K530 (Mus musculus)
MIB2:CYLD:UBE2D2 [cytosol] (Mus musculus)
Ub:UBE2D2 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
MIB2 ubiquitinates RIPK1 at K377, K604, K634 (Mus musculus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2:MIB2:Ub:UBE2D1 [plasma membrane] (Mus musculus)
Ub:UBE2D1 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
RIPK1 binds STUB1 (Mus musculus)
RIPK1:STUB1:Ub:UBE2D3 [cytosol] (Mus musculus)
Ub:UBE2D3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:UBE2D3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
STUB1 ubiquitinates RIPK1 at K571, K604, K627 (Mus musculus)
RIPK1:STUB1:Ub:UBE2D3 [cytosol] (Mus musculus)
Ub:UBE2D3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
p75 NTR receptor-mediated signalling (Mus musculus)
Cell death signalling via NRAGE, NRIF and NADE (Mus musculus)
NRIF signals cell death from the nucleus (Mus musculus)
Polyubiquitinated NRIF binds to p62 (Sequestosome) (Mus musculus)
Ubiquitinated NRIF [cytosol] (Mus musculus)
K63 linked polyubiquitin chain [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitinated NRIF:Sequestosome [cytosol] (Mus musculus)
K63 linked polyubiquitin chain [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Polyubiquitinated NRIF migrates to the nucleus (Mus musculus)
Ubiquitinated NRIF:Sequestosome [cytosol] (Mus musculus)
K63 linked polyubiquitin chain [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
TRAF6 polyubiquitinates NRIF (Mus musculus)
K63 linked polyubiquitin chain [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitinated NRIF [cytosol] (Mus musculus)
K63 linked polyubiquitin chain [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
p75NTR signals via NF-kB (Mus musculus)
NF-kB is activated and signals survival (Mus musculus)
IkB is ubiquitinated and degraded (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitinated phospho-IkB [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
p75NTR recruits signalling complexes (Mus musculus)
TRAF6 is auto-ubiquitinated (Mus musculus)
Ub [cytosol] (Mus musculus)
Intracellular signaling by second messengers (Mus musculus)
PIP3 activates AKT signaling (Mus musculus)
PTEN Regulation (Mus musculus)
Regulation of PTEN localization (Mus musculus)
PTEN undergoes monoubiquitination (Mus musculus)
Ub [cytosol] (Mus musculus)
Regulation of PTEN stability and activity (Mus musculus)
MKRN1 polyubiquitinates PTEN (Mus musculus)
Ub [cytosol] (Mus musculus)
NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Mus musculus)
Ub [cytosol] (Mus musculus)
Proteasome degrades polyubiquitinated PTEN (Mus musculus)
Ub [cytosol] (Mus musculus)
RNF146 polyubiquitinates PARylated PTEN (Mus musculus)
Ub [cytosol] (Mus musculus)
TRIM27 polyubiquitinates PTEN (Mus musculus)
Ub [cytosol] (Mus musculus)
USP13 and OTUD3 deubiquitinate PTEN (Mus musculus)
Ub [cytosol] (Mus musculus)
MAPK family signaling cascades (Mus musculus)
MAPK1/MAPK3 signaling (Mus musculus)
RAF/MAP kinase cascade (Mus musculus)
Negative regulation of MAPK pathway (Mus musculus)
BRAP autoubiquitinates (Mus musculus)
Ub [cytosol] (Mus musculus)
Regulation of RAS by GAPs (Mus musculus)
KBTBD7:CUL3:RBX1 ubiquitinates NF1 (Mus musculus)
Ub [cytosol] (Mus musculus)
MAPK6/MAPK4 signaling (Mus musculus)
MAPK6 is degraded by the 26S proteasome (Mus musculus)
Ub [cytosol] (Mus musculus)
Signaling by Hedgehog (Mus musculus)
Hedgehog 'off' state (Mus musculus)
Degradation of GLI1 by the proteasome (Mus musculus)
SCF(beta-TrCP) ubiquitinates p-GLI1 (Mus musculus)
Ub [cytosol] (Mus musculus)
GLI3 is processed to GLI3R by the proteasome (Mus musculus)
SCF(beta-TrCP) ubiquitinates p-GLI3 (Mus musculus)
Ub [cytosol] (Mus musculus)
Hedgehog 'on' state (Mus musculus)
NUMB:ITCH ubiquitinates GLI1 (Mus musculus)
Ub [cytosol] (Mus musculus)
ub-GLI is degraded by the proteasome (Mus musculus)
Ub [cytosol] (Mus musculus)
Hedgehog ligand biogenesis (Mus musculus)
Hh C-terminal fragments are degraded by the proteasome (Mus musculus)
Ub [cytosol] (Mus musculus)
SYVN1 ubiquitinates Hh C-terminal fragments (Mus musculus)
Ub [cytosol] (Mus musculus)
Signaling by NOTCH (Mus musculus)
Signaling by NOTCH1 (Mus musculus)
Activated NOTCH1 Transmits Signal to the Nucleus (Mus musculus)
ITCH ubiquitinates DTX (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub-DTX:ITCH [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Signaling by NOTCH3 (Mus musculus)
NOTCH3 Activation and Transmission of Signal to the Nucleus (Mus musculus)
WWP2 ubiquitinates NOTCH3 (Mus musculus)
Ub [cytosol] (Mus musculus)
Signaling by Non-Receptor Tyrosine Kinases (Mus musculus)
Signaling by PTK6 (Mus musculus)
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 (Mus musculus)
CBL autoubiquitinates (Mus musculus)
Ub [cytosol] (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by EGFR (Mus musculus)
EGFR downregulation (Mus musculus)
CBL binds and ubiquitinates phosphorylated Sprouty (Mus musculus)
EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane] (Mus musculus)
Ub-p-Y53/55-SPRY1/2 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub-Beta-Pix:CDC42:GTP [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
CBL ubiquitinates Sprouty (Mus musculus)
EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane] (Mus musculus)
Ub-p-Y53/55-SPRY1/2 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
CBL-mediated ubiquitination of CIN85 (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitination of stimulated EGFR (CBL) (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitination of stimulated EGFR (CBL:GRB2) (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Signaling by ERBB2 (Mus musculus)
Downregulation of ERBB2 signaling (Mus musculus)
CHIP (STUB1) mediates ubiquitination of ERBB2 (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub-ERBB2:ERBIN:Ub-HSP90:CDC37 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
CUL5 mediates ubiquitination of ERBB2 (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub-ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Downregulation of ERBB2:ERBB3 signaling (Mus musculus)
Deubiquitination of RNF41 by P-USP8 (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub-RNF41:p-USP8 [cytosol] (Mus musculus)
Ub-RNF41 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
RNF41 ubiquitinates ERBB3 (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub-ERBB3 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
RNF41 ubiquitinates activated ERBB3 (Mus musculus)
NRG1/2:Ub-p-10Y-ERBB3:p-ERBB2 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Self-ubiquitination of RNF41 (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub-RNF41 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitinated RNF41 binds P-USP8 (Mus musculus)
Ub-RNF41 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub-RNF41:p-USP8 [cytosol] (Mus musculus)
Ub-RNF41 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Signaling by ERBB4 (Mus musculus)
Downregulation of ERBB4 signaling (Mus musculus)
ERBB4 ubiquitination by WWP1/ITCH (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub-ERBB4:WWP1/ITCH [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
NEDD4 ubiquitinates ERBB4jmAcyt1s80 dimer (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub-ERBB4jmAcyt1s80:NEDD4 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Signaling by FGFR (Mus musculus)
Signaling by FGFR1 (Mus musculus)
Negative regulation of FGFR1 signaling (Mus musculus)
CBL ubiquitinates FRS2 and FGFR1 (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub-Activated FGFR1 complex:Ub-p-FRS2 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Spry regulation of FGF signaling (Mus musculus)
CBL dissociates from ubiquitinated p-SPRY2 (Mus musculus)
Ub-(Y55/Y227)p-SPRY2 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:Y55/Y227-pSPRY2:CBL [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Phosphorylated SPRY2 is ubiquitinated by CBL (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:Y55/Y227-pSPRY2:CBL [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Signaling by FGFR2 (Mus musculus)
Negative regulation of FGFR2 signaling (Mus musculus)
CBL ubiquitinates FRS2 and FGFR2 (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub-Activated FGFR2 complex:Ub-p-FRS2 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Spry regulation of FGF signaling (Mus musculus)
CBL dissociates from ubiquitinated p-SPRY2 (Mus musculus)
Ub-(Y55/Y227)p-SPRY2 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:Y55/Y227-pSPRY2:CBL [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Phosphorylated SPRY2 is ubiquitinated by CBL (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:Y55/Y227-pSPRY2:CBL [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Signaling by FGFR3 (Mus musculus)
Negative regulation of FGFR3 signaling (Mus musculus)
CBL ubiquitinates FRS2 and FGFR3 (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub-Activated FGFR3 complex:Ub-p-FRS2 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Spry regulation of FGF signaling (Mus musculus)
CBL dissociates from ubiquitinated p-SPRY2 (Mus musculus)
Ub-(Y55/Y227)p-SPRY2 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:Y55/Y227-pSPRY2:CBL [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Phosphorylated SPRY2 is ubiquitinated by CBL (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:Y55/Y227-pSPRY2:CBL [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Signaling by FGFR4 (Mus musculus)
Negative regulation of FGFR4 signaling (Mus musculus)
CBL ubiquitinates FRS2 and FGFR4 (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub-Activated FGFR4 complex:Ub-p-FRS2 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Spry regulation of FGF signaling (Mus musculus)
CBL dissociates from ubiquitinated p-SPRY2 (Mus musculus)
Ub-(Y55/Y227)p-SPRY2 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:Y55/Y227-pSPRY2:CBL [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Phosphorylated SPRY2 is ubiquitinated by CBL (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub:Y55/Y227-pSPRY2:CBL [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Signaling by MET (Mus musculus)
Negative regulation of MET activity (Mus musculus)
CBL monoubiquitinates activated MET (Mus musculus)
Ub [cytosol] (Mus musculus)
USP8 deubiquitinates LRIG1 (Mus musculus)
Ub [cytosol] (Mus musculus)
Signaling by TGFB family members (Mus musculus)
Signaling by TGF-beta Receptor Complex (Mus musculus)
TGF-beta receptor signaling activates SMADs (Mus musculus)
Downregulation of TGF-beta receptor signaling (Mus musculus)
Degradation of TGF-beta receptor complex (Mus musculus)
TGFB1:TGFBR2:Ub-p-TGFBR1:Ub-SMAD7 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Degradation of ubiquitinated SMAD2 (Mus musculus)
Ub-SMAD2 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Degradation of ubiquitinated SMAD3 (Mus musculus)
Ub-SMAD3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
SMURF2 ubiquitinates SMAD2 (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub-SMAD2 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
STUB1 (CHIP) ubiquitinates SMAD3 (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub-SMAD3 [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) (Mus musculus)
Disassembly of tight junctions (Mus musculus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Mus musculus)
Ub [cytosol] (Mus musculus)
SMURF1 ubiquitinates RHOA (Mus musculus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Mus musculus)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Mus musculus)
USP9X (FAM) deubiquitinates SMAD4 (Mus musculus)
Ub [cytosol] (Mus musculus)
Signaling by WNT (Mus musculus)
Beta-catenin independent WNT signaling (Mus musculus)
PCP/CE pathway (Mus musculus)
Asymmetric localization of PCP proteins (Mus musculus)
SMURF1/2 ubiquitinates PRICKLE1 (Mus musculus)
Ub [cytosol] (Mus musculus)
Degradation of beta-catenin by the destruction complex (Mus musculus)
Degradation of ubiquitinated beta catenin by the proteasome (Mus musculus)
Ub [cytosol] (Mus musculus)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Mus musculus)
Ub [cytosol] (Mus musculus)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
TCF dependent signaling in response to WNT (Mus musculus)
Degradation of AXIN (Mus musculus)
AXIN is ubiquitinated by SMURF2 (Mus musculus)
Ub [cytosol] (Mus musculus)
RNF146 ubiquitinates ADP-ribosylated AXIN (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub-RibC-AXIN is degraded by the proteasome (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitinated AXIN is degraded by the proteasome (Mus musculus)
Ub [cytosol] (Mus musculus)
Degradation of DVL (Mus musculus)
DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Mus musculus)
Ub [cytosol] (Mus musculus)
DVL1 is ubiquitinated by HECW1 (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitinated DVL is degraded by the proteasome (Mus musculus)
Ub [cytosol] (Mus musculus)
Ubiquitinated DVL1 is degraded by the proteasome (Mus musculus)
Ub [cytosol] (Mus musculus)
Regulation of FZD by ubiquitination (Mus musculus)
USP8 deubiquitinates FZD to potentiate WNT signaling (Mus musculus)
Ub [cytosol] (Mus musculus)
ZNRF3 autoubiquitinates to promote its internalization (Mus musculus)
Ub [cytosol] (Mus musculus)
ZNRF3 ubiquitinates FZD to promote its downregulation (Mus musculus)
Ub [cytosol] (Mus musculus)
USP34 deubiquitinates AXIN1,AXIN2 (Mus musculus)
Ub [cytosol] (Mus musculus)
Transport of small molecules (Mus musculus)
ABC-family proteins mediated transport (Mus musculus)
RNF5 and RNF185 ubiquitinate misfolded CFTR (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] (Mus musculus)
Ub-misfolded nascent CFTR [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Mus musculus)
Ub-misfolded nascent CFTR [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] (Mus musculus)
Ub-misfolded nascent CFTR [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
misfolded CFTR is degraded by the 26S proteasome (Mus musculus)
Ub [cytosol] (Mus musculus)
Ub-misfolded nascent CFTR [cytosol] (Mus musculus)
Ub [cytosol] (Mus musculus)
Ion channel transport (Mus musculus)
Stimuli-sensing channels (Mus musculus)
RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels (Mus musculus)
Ub [cytosol] (Mus musculus)
Iron uptake and transport (Mus musculus)
SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 (Mus musculus)
Ub [cytosol] (Mus musculus)
Vesicle-mediated transport (Mus musculus)
Membrane Trafficking (Mus musculus)
Clathrin-mediated endocytosis (Mus musculus)
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Mus musculus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Mus musculus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
BAR domain proteins recruit dynamin (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Mus musculus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Mus musculus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Cargo recognition for clathrin-mediated endocytosis (Mus musculus)
Epsin family proteins bind ubiquitinated cargo (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Clathrin recruits PIK3C2A (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Clathrin recruits auxilins to the clathrin-coated vesicle (Mus musculus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Mus musculus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Mus musculus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Endophilins recruit synaptojanins to the clathrin-coated pit (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Mus musculus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Mus musculus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
F- and N- BAR domain proteins bind the clathrin-coated pit (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Mus musculus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Mus musculus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Mus musculus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
RAB5 and GAPVD1 bind AP-2 (Mus musculus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Mus musculus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Mus musculus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Mus musculus)
Ub [cytosol] (Mus musculus)
Participants
members
Ubiquitin (Pps27a) [cytosol]
(Mus musculus)
Ubiquitin (Uba52) [cytosol]
(Mus musculus)
Ubiquitin (Ubc 1) [cytosol]
(Mus musculus)
Ubiquitin (Ubc 2) [cytosol]
(Mus musculus)
Ubiquitin (Ubc 3) [cytosol]
(Mus musculus)
Ubiquitin (Ubb 1) [cytosol]
(Mus musculus)
Ubiquitin (Ubb 2) [cytosol]
(Mus musculus)
Ubiquitin (Ubb 3) [cytosol]
(Mus musculus)
Ubiquitin (Ubb 4) [cytosol]
(Mus musculus)
Ubb [cytosol]
(Mus musculus)
Participates
as a component of
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Ub:PEX5L [cytosol] (Mus musculus)
USP5:Ub [cytosol] (Mus musculus)
UCHL1,UCHL3:Ub [cytosol] (Mus musculus)
Ub:E2 (UBA6 substrate) [cytosol] (Mus musculus)
Ub-Cys625-UBA6 [cytosol] (Mus musculus)
Ub:E2 (UBA1 substrate) [cytosol] (Mus musculus)
Ub-Cys632-UBA1 [cytosol] (Mus musculus)
Ub:PEX5L [peroxisomal membrane] (Mus musculus)
Ub:UBE2D1,UBE2D2,UBE2D3, UBE2E1,UBE2N [cytosol] (Mus musculus)
Ub:UBE2N [cytosol] (Mus musculus)
Ub:UBE2D1,2,3 [cytosol] (Mus musculus)
Ub-ERBB4:WWP1/ITCH [plasma membrane] (Mus musculus)
Ub-ERBB4jmAcyt1s80:NEDD4 [cytosol] (Mus musculus)
Ub-DTX:ITCH [cytosol] (Mus musculus)
Ub:UBE2D1 [cytosol] (Mus musculus)
Ub:UBE2D2 [cytosol] (Mus musculus)
ubiquitinated Cdc6 [cytosol] (Mus musculus)
Ub-Activated FGFR4 complex:Ub-p-FRS2 [plasma membrane] (Mus musculus)
Ub-p-S124-CDC25A [cytosol] (Mus musculus)
ubiquitinated phospho-COP1(ser-387) [cytosol] (Mus musculus)
Ub-Activated FGFR3 complex:Ub-p-FRS2 [plasma membrane] (Mus musculus)
Ub-unfolded protein:(GlcNAc)2 (Man)9-5 [endoplasmic reticulum quality control compartment] (Mus musculus)
Ub-unfolded protein:(GlcNAc)2 (Man)9-5 [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
Ub-Activated FGFR2 complex:Ub-p-FRS2 [plasma membrane] (Mus musculus)
NFKB1:RELA:p-S32,S36-NFKBIA:Ub [cytosol] (Mus musculus)
multi-ubiquitinated phospho-(T286) Cyclin D1 [cytosol] (Mus musculus)
Ub-p-S252,S497,T501-BORA [cytosol] (Mus musculus)
K63 linked polyubiquitin chain [cytosol] (Mus musculus)
Ubiquitinated phospho-IkB [cytosol] (Mus musculus)
Ub-Activated FGFR1 complex:Ub-p-FRS2 [plasma membrane] (Mus musculus)
Ub-(Y55/Y227)p-SPRY2 [plasma membrane] (Mus musculus)
Ub:Y55/Y227-pSPRY2:CBL [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Mus musculus)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL [plasma membrane] (Mus musculus)
Ub-p-Y53/55-SPRY1/2 [cytosol] (Mus musculus)
Ub-Beta-Pix:CDC42:GTP [cytosol] (Mus musculus)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Mus musculus)
Ub-ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Mus musculus)
NRG1/2:Ub-p-10Y-ERBB3:p-ERBB2 [plasma membrane] (Mus musculus)
Ub-ERBB3 [plasma membrane] (Mus musculus)
Ub-RNF41 [cytosol] (Mus musculus)
Ub-ERBB2:ERBIN:Ub-HSP90:CDC37 [plasma membrane] (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ub:UBE2D3 [cytosol] (Mus musculus)
UBE2D1,2,3:Ubiquitin [cytosol] (Mus musculus)
multiubiquitinated STAT2 [cytosol] (Mus musculus)
E1 bound ubiquitin [cytosol] (Mus musculus)
Ubiquitin:E2 conjugating enzymes [cytosol] (Mus musculus)
Ub:substrate [cytosol] (Mus musculus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Mus musculus)
TGFB1:TGFBR2:Ub-p-TGFBR1:Ub-SMAD7 [plasma membrane] (Mus musculus)
Ub-misfolded nascent CFTR [cytosol] (Mus musculus)
Ub:UBE2N:UBE2V1 [cytosol] (Mus musculus)
Ub:Ub-UBE2D2,UBE2D3,UBE2N:UBE2V1,UBE2L3 [cytosol] (Mus musculus)
SCF-associated multiubiquitinated Emi1complexes [cytosol] (Mus musculus)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Mus musculus)
Multiubiquitinated Nek2A [cytosol] (Mus musculus)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Mus musculus)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Mus musculus)
Ub-SMAD3 [cytosol] (Mus musculus)
Ub-SMAD2 [cytosol] (Mus musculus)
as an input of
AUF1 (hnRNP D0) is ubiquitinylated (Mus musculus)
Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol (Mus musculus)
UBA1 adenylates ubiquitin in the cytosol (Mus musculus)
SYVN1 ubiquitinates Hh C-terminal fragments (Mus musculus)
Ubiquitination of FLT3 (Mus musculus)
TRIM21 ubiquitinates SQSTM1 (Mus musculus)
MUL1 ubiquitinates UBXN7 (Mus musculus)
RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels (Mus musculus)
RNF5 and RNF185 ubiquitinate misfolded CFTR (Mus musculus)
CUL3:RBX1 ubiquitinates KEAP1 (Mus musculus)
KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer (Mus musculus)
KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 (Mus musculus)
ERBB4 ubiquitination by WWP1/ITCH (Mus musculus)
NEDD4 ubiquitinates ERBB4jmAcyt1s80 dimer (Mus musculus)
ITCH polyubiquitinates TP73 (Mus musculus)
NUMB:ITCH ubiquitinates GLI1 (Mus musculus)
SCF(beta-TrCP) ubiquitinates p-GLI1 (Mus musculus)
STUB1 polyubiquitinates RUNX2 (Mus musculus)
SCF(beta-TrCP) ubiquitinates p-GLI3 (Mus musculus)
WWP2 ubiquitinates NOTCH3 (Mus musculus)
ITCH ubiquitinates DTX (Mus musculus)
DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3 (Mus musculus)
DDX41 ubiquitination by TRIM21 (Mus musculus)
STING ubiquitination by TRIM32 or TRIM56 (Mus musculus)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Mus musculus)
CBL ubiquitinates FRS2 and FGFR4 (Mus musculus)
Autoubiquitination of phospho-COP1(Ser-387 ) (Mus musculus)
SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 (Mus musculus)
CBL ubiquitinates FRS2 and FGFR3 (Mus musculus)
CTLH E3 ligase ubiquitinates PKM-1 (Mus musculus)
CTLH E3 ligase ubiquitinates LDHA (Mus musculus)
CBL ubiquitinates FRS2 and FGFR2 (Mus musculus)
Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex (Mus musculus)
SCF-beta-TrCp1/2 ubiquitinates phosphorylated BORA (Mus musculus)
SCF-FBXL18 ubiquitinates FBXL7 (Mus musculus)
SCF-FBXL7 ubiquitinates AURKA (Mus musculus)
SCF-beta-TrCP ubiquitinylates IkB (Mus musculus)
IkB is ubiquitinated and degraded (Mus musculus)
TRAF6 is auto-ubiquitinated (Mus musculus)
CBL monoubiquitinates activated MET (Mus musculus)
CBL ubiquitinates FRS2 and FGFR1 (Mus musculus)
Phosphorylated SPRY2 is ubiquitinated by CBL (Mus musculus)
Ubiquitination of stimulated EGFR (CBL:GRB2) (Mus musculus)
Ubiquitination of stimulated EGFR (CBL) (Mus musculus)
CBL binds and ubiquitinates phosphorylated Sprouty (Mus musculus)
CBL ubiquitinates Sprouty (Mus musculus)
CBL-mediated ubiquitination of CIN85 (Mus musculus)
CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix (Mus musculus)
CBL autoubiquitinates (Mus musculus)
Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Mus musculus)
AXIN is ubiquitinated by SMURF2 (Mus musculus)
RNF146 ubiquitinates ADP-ribosylated AXIN (Mus musculus)
DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Mus musculus)
DVL1 is ubiquitinated by HECW1 (Mus musculus)
ZNRF3 autoubiquitinates to promote its internalization (Mus musculus)
ZNRF3 ubiquitinates FZD to promote its downregulation (Mus musculus)
SMURF1/2 ubiquitinates PRICKLE1 (Mus musculus)
CUL5 mediates ubiquitination of ERBB2 (Mus musculus)
RNF41 ubiquitinates ERBB3 (Mus musculus)
RNF41 ubiquitinates activated ERBB3 (Mus musculus)
Self-ubiquitination of RNF41 (Mus musculus)
CHIP (STUB1) mediates ubiquitination of ERBB2 (Mus musculus)
KBTBD7:CUL3:RBX1 ubiquitinates NF1 (Mus musculus)
BRAP autoubiquitinates (Mus musculus)
MKRN1 polyubiquitinates PTEN (Mus musculus)
RNF146 polyubiquitinates PARylated PTEN (Mus musculus)
TRIM27 polyubiquitinates PTEN (Mus musculus)
NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Mus musculus)
PTEN undergoes monoubiquitination (Mus musculus)
STUB1 ubiquitinates RIPK3 at K55, K363 (Mus musculus)
IKKε (IKBKE) is ubiquitinated within the activated TLR4 (Mus musculus)
TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 (Mus musculus)
Auto-ubiquitination of TRAF3 (Mus musculus)
TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TRIF:activated TLR4 (Mus musculus)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation (Mus musculus)
Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
E1 mediated ubiquitin activation (Mus musculus)
SMURF1 ubiquitinates RHOA (Mus musculus)
ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (Mus musculus)
Ubiquitination of Emi1 by SCF-beta-TrCP (Mus musculus)
Multiubiquitination of Nek2A (Mus musculus)
Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Mus musculus)
Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Mus musculus)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Mus musculus)
Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 (Mus musculus)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Mus musculus)
Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer (Mus musculus)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon ALPK1:ADP-heptose stimulation (Mus musculus)
TRAF2,6 ubiquitinates NLRC5 (Mus musculus)
Auto ubiquitination of TRAF6 bound to the activated TLR4 complex (Mus musculus)
SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2 (Mus musculus)
Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Mus musculus)
STUB1 (CHIP) ubiquitinates SMAD3 (Mus musculus)
SMURF2 ubiquitinates SMAD2 (Mus musculus)
as an output of
MAPK6 is degraded by the 26S proteasome (Mus musculus)
USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin (Mus musculus)
OTUD7A hydrolyses K11diUb (Mus musculus)
USP5 cleaves polyubiquitin (Mus musculus)
USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 (Mus musculus)
USP8 deubiquitinates STAM2:HGS (Mus musculus)
26S proteasome degrades HIFalpha (Mus musculus)
Hh C-terminal fragments are degraded by the proteasome (Mus musculus)
USP33 deubiquitinates ROBO1 (Mus musculus)
ub UBXN7 is degraded by the 26S proteasome (Mus musculus)
misfolded CFTR is degraded by the 26S proteasome (Mus musculus)
26S proteasome degrades Ub-NFE2L2 (Mus musculus)
26S proteasome degrades TP73 polyubiquitinated by ITCH (Mus musculus)
ub-GLI is degraded by the proteasome (Mus musculus)
Polyubiquitinated RUNX3 is degraded by the proteasome (Mus musculus)
26S proteasome processes p-7S-p100:RELB to form p52:RELB (Mus musculus)
CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex (Mus musculus)
CYLD hydrolyses M1polyUb on RIPK1 within the TNFR1 complex (Mus musculus)
K63polyUb-RIPK1 is deubiquitinated (Mus musculus)
Ubiquitinated Cdc6 is degraded by the proteasome (Mus musculus)
Ubiquitinated Orc1 is degraded by the proteasome (Mus musculus)
Proteolytic degradation of ubiquitinated-Cdc25A (Mus musculus)
Proteasome mediated degradation of COP1 (Mus musculus)
Proteasome proteolyzes ub-HIF-alpha (Mus musculus)
Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex (Mus musculus)
Proteasome mediated degradation of Cyclin D1 (Mus musculus)
Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Mus musculus)
Proteasome-mediated degradation of PolyUb-FBXL7 (Mus musculus)
USP8 deubiquitinates LRIG1 (Mus musculus)
Degradation of ubiquitinated beta catenin by the proteasome (Mus musculus)
USP34 deubiquitinates AXIN1,AXIN2 (Mus musculus)
Ubiquitinated AXIN is degraded by the proteasome (Mus musculus)
Ub-RibC-AXIN is degraded by the proteasome (Mus musculus)
Ubiquitinated DVL1 is degraded by the proteasome (Mus musculus)
Ubiquitinated DVL is degraded by the proteasome (Mus musculus)
USP8 deubiquitinates FZD to potentiate WNT signaling (Mus musculus)
Deubiquitination of RNF41 by P-USP8 (Mus musculus)
Proteasome degrades polyubiquitinated PTEN (Mus musculus)
USP13 and OTUD3 deubiquitinate PTEN (Mus musculus)
CYLD mediated deubiquitination of DDX58 (RIG-I) (Mus musculus)
Proteasomal cleavage of substrate (Mus musculus)
USP30 deubiquitinates ATM dimer:Ub-p-PEX5 (Mus musculus)
Degradation multiubiquitinated Cyclin A (Mus musculus)
Degradation of multiubiquitinated Cyclin B (Mus musculus)
Degradation of multiubiquitinated Securin (Mus musculus)
USP14 deubiquitinates NLRC5 (Mus musculus)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Mus musculus)
USP9X (FAM) deubiquitinates SMAD4 (Mus musculus)
Degradation of multiubiquitinated cell cycle proteins (Mus musculus)
Degradation of multiubiquitinated Nek2A (Mus musculus)
GTSE1 facilitates proteasome-mediated degradation of TP53 (Mus musculus)
Inferred From
Ub [cytosol]
(Homo sapiens)
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