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Ccnd2 [nucleoplasm]
Stable Identifier
R-MMU-113827
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
nucleoplasm
Synonyms
CCND2, P30280
Locations in the PathwayBrowser
Expand all
Cell Cycle (Mus musculus)
Cell Cycle, Mitotic (Mus musculus)
Mitotic G1 phase and G1/S transition (Mus musculus)
G1 Phase (Mus musculus)
Cyclin D associated events in G1 (Mus musculus)
CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 (Mus musculus)
CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Mus musculus)
CDK4,CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Mus musculus)
CDK4/6:CCND [nucleoplasm] (Mus musculus)
Cyclin D [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
CDK4:CCND [nucleoplasm] (Mus musculus)
Cyclin D2:Cdk4 [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
CDK6:CCND [nucleoplasm] (Mus musculus)
Cyclin D2:Cdk6 [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
Cyclin D:CDK4,CDK6:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Mus musculus)
Cyclin D [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Mus musculus)
Cyclin D [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Mus musculus)
Cyclin D [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
p-T172-CDK4:CCND [nucleoplasm] (Mus musculus)
p-T172-CDK4:CCND2 [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
p-T177-CDK6:CCND [nucleoplasm] (Mus musculus)
p-T177-CDK6:CCND2 [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Mus musculus)
Cyclin D [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Mus musculus)
Cyclin D [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
p-T172-CDK4:CCND [nucleoplasm] (Mus musculus)
p-T172-CDK4:CCND2 [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
p-T177-CDK6:CCND [nucleoplasm] (Mus musculus)
p-T177-CDK6:CCND2 [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Mus musculus)
Cyclin D [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Mus musculus)
Cyclin D [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
p-T172-CDK4:CCND [nucleoplasm] (Mus musculus)
p-T172-CDK4:CCND2 [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
p-T177-CDK6:CCND [nucleoplasm] (Mus musculus)
p-T177-CDK6:CCND2 [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
p-T172-CDK4:CCND:CDK4 inhibitors [nucleoplasm] (Mus musculus)
p-T172-CDK4:CCND2:CDK4 inhibitors (CCND2) [nucleoplasm] (Mus musculus)
p-T172-CDK4:CCND2 [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
p-T177-CDK6:CCND:CDK6 inhibitors [nucleoplasm] (Mus musculus)
p-T177-CDK6:CCND2:CDK6 inhibitors (CCND2) [nucleoplasm] (Mus musculus)
p-T177-CDK6:CCND2 [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Mus musculus)
Cyclin D [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Mus musculus)
Cyclin D [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
p-T172-CDK4:CCND [nucleoplasm] (Mus musculus)
p-T172-CDK4:CCND2 [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
p-T177-CDK6:CCND [nucleoplasm] (Mus musculus)
p-T177-CDK6:CCND2 [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
Drug-mediated inhibition of CDK4/CDK6 activity (Mus musculus)
CDK4 inhibitors bind CDK4 (Mus musculus)
p-T172-CDK4:CCND [nucleoplasm] (Mus musculus)
p-T172-CDK4:CCND2 [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
p-T172-CDK4:CCND:CDK4 inhibitors [nucleoplasm] (Mus musculus)
p-T172-CDK4:CCND2:CDK4 inhibitors (CCND2) [nucleoplasm] (Mus musculus)
p-T172-CDK4:CCND2 [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
CDK6 inhibitors bind CDK6 (Mus musculus)
p-T177-CDK6:CCND [nucleoplasm] (Mus musculus)
p-T177-CDK6:CCND2 [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
p-T177-CDK6:CCND:CDK6 inhibitors [nucleoplasm] (Mus musculus)
p-T177-CDK6:CCND2:CDK6 inhibitors (CCND2) [nucleoplasm] (Mus musculus)
p-T177-CDK6:CCND2 [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
RB1 binds and inhibits E2F1/2/3:DP1/2 complexes (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Mus musculus)
Cyclin D [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Mus musculus)
Cyclin D [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
p-T172-CDK4:CCND [nucleoplasm] (Mus musculus)
p-T172-CDK4:CCND2 [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
p-T177-CDK6:CCND [nucleoplasm] (Mus musculus)
p-T177-CDK6:CCND2 [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus (Mus musculus)
CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Mus musculus)
CDK4,CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Mus musculus)
CDK4/6:CCND [nucleoplasm] (Mus musculus)
Cyclin D [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
CDK4:CCND [nucleoplasm] (Mus musculus)
Cyclin D2:Cdk4 [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
CDK6:CCND [nucleoplasm] (Mus musculus)
Cyclin D2:Cdk6 [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
Cyclin D:CDK4,CDK6:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Mus musculus)
Cyclin D [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional regulation by RUNX1 (Mus musculus)
Regulation of RUNX1 Expression and Activity (Mus musculus)
CBFB binds RUNX1 (Mus musculus)
RUNX1:CCND3,(CCND1,CCND2) [nucleoplasm] (Mus musculus)
CCND3,(CCND1,CCND2) [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
CCND3,(CCND1,CCND2) binds RUNX1 (Mus musculus)
CCND3,(CCND1,CCND2) [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
RUNX1:CCND3,(CCND1,CCND2) [nucleoplasm] (Mus musculus)
CCND3,(CCND1,CCND2) [nucleoplasm] (Mus musculus)
Ccnd2 [nucleoplasm] (Mus musculus)
External Reference Information
External Reference
UniProt:P30280
Gene Names
Ccnd2
Reference Genes
BioGPS Gene:12444 Ccnd2
ENSEMBL:ENSMUSG00000000184
KEGG:mmu:12444 Ccnd2
Monarch:12444 Ccnd2
NCBI Gene:12444 Ccnd2
UCSC:P30280 Ccnd2
Reference Transcript
RefSeq:XM_006505460.1 Ccnd2
RefSeq:XM_006505459.3 Ccnd2
RefSeq:NM_009829.3 Ccnd2
Other Identifiers
10548105
12444
1416122_at
1416123_at
1416124_at
1430127_a_at
1434745_at
1448229_s_at
1455956_x_at
17471222
4463247
4498461
4549571
4568379
4585645
4738271
4784936
4880961
4979962
5021276
5105484
5159188
5219476
5245311
5514226
5577613
5611449
97504_at
A_52_P514391
A_52_P53906
A_65_P18532
GE35166
GO:0000082
GO:0000307
GO:0000785
GO:0005515
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0005815
GO:0005829
GO:0007616
GO:0008284
GO:0008344
GO:0016020
GO:0016538
GO:0019901
GO:0031965
GO:0043066
GO:0043539
GO:0050877
GO:0051301
GO:0051726
GO:0061575
GO:0071481
GO:0097129
GO:0098772
GO:1900087
ILMN_1217770
ILMN_1225932
ILMN_1235724
ILMN_2700166
ILMN_2700168
Msa.25099.0_s_at
m83749_s_at
mMC008669
mMC011981
Participates
as a candidate of
CCND3,(CCND1,CCND2) [nucleoplasm] (Mus musculus)
Cyclin D [nucleoplasm] (Mus musculus)
as a component of
Cyclin D2:Cdk4 [nucleoplasm] (Mus musculus)
Cyclin D2:Cdk6 [nucleoplasm] (Mus musculus)
p-T177-CDK6:CCND2 [nucleoplasm] (Mus musculus)
p-T172-CDK4:CCND2 [nucleoplasm] (Mus musculus)
Other forms of this molecule
Ccnd2 [cytosol]
Inferred From
CCND2 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_033959.1
,
XP_006505522.1
,
XP_006505523.1
ENSEMBL
ENSMUSP00000000188
,
ENSMUSG00000000184
,
ENSMUST00000000188
PRO
P30280
MGI
88314
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P30285 Cdk4
6
CDK4 [nucleoplasm]
(R-MMU-113730)
phospho-Cdk4(Thr 286) [nucleoplasm]
(R-MMU-182559)
Cdk4 [nucleoplasm]
(R-MMU-182567)
CDK4 [cytosol]
(R-MMU-68330)
CDK4 [nucleoplasm]
(R-MMU-113843)
phospho-p-T172-CDK4 [nucleoplasm]
(R-MMU-113830)
0.527
2
UniProt:Q64261
3
CDK6 [cytosol]
(R-MMU-68336)
CDK6 [nucleoplasm]
(R-MMU-141283)
phospho-p-T177-CDK6 [nucleoplasm]
(R-MMU-69628)
0.462
3
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