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PLC gamma1,2 [cytosol]
Stable Identifier
R-MMU-1169089
Type
Set [DefinedSet]
Species
Mus musculus
Compartment
cytosol
Synonyms
Phospholipase C gamma1 and Phospholipase C gamma2
Locations in the PathwayBrowser
Expand all
Immune System (Mus musculus)
Innate Immune System (Mus musculus)
DAP12 interactions (Mus musculus)
DAP12 signaling (Mus musculus)
Activation of RAC1 by VAV2/3 (Mus musculus)
p-5Y-LAT:PLCG1:GADS:p-3Y-SLP-76:BTK:p-VAV [plasma membrane] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
Phosphorylation and activation of VAV2/VAV3 by SYK (Mus musculus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG:VAV:BTK:PIP3 [plasma membrane] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
p-5Y-LAT:PLCG1:GADS:p-3Y-SLP-76:BTK:p-VAV [plasma membrane] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
Phosphorylation of BTK by p-SYK (Mus musculus)
p-5Y-LAT:GRB2:SOS1:GADS:p-3Y-SLP-76:PLCG:VAV:p-Y223,Y551-BTK [plasma membrane] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG:VAV:BTK:PIP3 [plasma membrane] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Mus musculus)
p-5Y-LAT:GRB2:SOS1:GADS:p-3Y-SLP-76:PLCG:VAV:p-Y223,Y551-BTK [plasma membrane] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
p-SYK/p-BTK [plasma membrane] (Mus musculus)
p-5Y-LAT:GRB2:SOS1:GADS:p-3Y-SLP-76:PLCG:VAV:p-Y223,Y551-BTK [plasma membrane] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
Phosphorylation of SLP-76 by p-SYK (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:SLP76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
Recruitment of PLC-gamma to SLP-76 and p-5Y-LAT (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:SLP76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
Recruitment of VAV and BTK to p-SLP-76 (Mus musculus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG:VAV:BTK:PIP3 [plasma membrane] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
Fc epsilon receptor (FCERI) signaling (Mus musculus)
FCERI mediated Ca+2 mobilization (Mus musculus)
Autophosphorylation of BTK/ITK (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-2Y-TEC kinases [plasma membrane] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-TEC kinases:PIP3 [plasma membrane] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
Phosphorylation of TEC kinases by p-SYK (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:TEC kinases:PIP3 [plasma membrane] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-TEC kinases:PIP3 [plasma membrane] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
FCERI mediated MAPK activation (Mus musculus)
Activation of RAC1 by VAV (Mus musculus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
Autophosphorylation of PAK (Mus musculus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane] (Mus musculus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
Phosphorylation and activation of VAV (Mus musculus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV [plasma membrane] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
Phosphorylation of SLP-76 by p-SYK (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:SLP76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
Recruitment of PAK to the membrane by binding active RAC1 (Mus musculus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane] (Mus musculus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
Recruitment of PLC-gamma to SLP-76 and p-5Y-LAT (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:SLP76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
Recruitment of VAV to p-SLP-76 (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV [plasma membrane] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
Fcgamma receptor (FCGR) dependent phagocytosis (Mus musculus)
Role of phospholipids in phagocytosis (Mus musculus)
Phosphorylation and activation of PLCG (Mus musculus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
Recruitment of PLCgamma to membrane (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:PLCG [plasma membrane] (Mus musculus)
PLC gamma1,2 [cytosol] (Mus musculus)
Participants
members
PLCG1 [cytosol]
(Mus musculus)
Plcg2 [cytosol]
(Mus musculus)
Participates
as an input of
Recruitment of PLC-gamma to SLP-76 and p-5Y-LAT (Mus musculus)
Recruitment of PLCgamma to membrane (Mus musculus)
as a component of
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:SLP76:PLCG [plasma membrane] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Mus musculus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:PLCG [plasma membrane] (Mus musculus)
Inferred From
PLC gamma1,2 [cytosol]
(Homo sapiens)
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