Reactome | Hif1a [nucleoplasm]

Hif1a [nucleoplasm]

Stable Identifier

R-MMU-1234135

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

HIF1A, Q61221

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q61221

Gene Names

Hif1a

Reference Genes

BioGPS Gene:15251 HIF1A

ENSEMBL:ENSMUSG00000021109

KEGG:mmu:15251 HIF1A

Monarch:15251 HIF1A

NCBI Gene:15251 HIF1A

UCSC:Q61221 HIF1A

Reference Transcript

Participates

as an input of

Nuclear PHD1,3 hydroxylates proline residues on HIF1A (Mus musculus)

as a member of

Other forms of this molecule

Hif1a [cytosol]

Hif1a [nucleoplasm]

Hif1a [cytosol]

phospho-Hif1a [cytosol]

Hif1a [cytosol]

Inferred From

HIF1A [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_017170450.1, NP_001300849.1, NP_001300848.1, NP_034561.2

ENSEMBL

ENSMUST00000021530, ENSMUSP00000021530, ENSMUSG00000021109

ZINC - Substances

HIF1A_MOUSE

ZINC target

Q61221

PRO

Q61221

MGI

106918

ZINC - Predictions - Purchasable

HIF1A_MOUSE

PDB

4ZPR

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P53762 Arnt	2	Arnt [nucleoplasm] (R-MMU-9621312) Arnt [nucleoplasm] (R-MMU-1234098)	0.723	6
UniProt:P25233 NECD			0.508	2
UniProt:Q09472 EP300	5	EP300 [nucleoplasm] (R-HSA-381325) p-S,T-EP300 [nucleoplasm] (R-HSA-8878072) FOXO4-S-S-EP300 [nucleoplasm] (R-HSA-9617691) Foxo4-S-S-EP300 [nucleoplasm] (R-HSA-9617720) monoSUMO1-K1020,1024-EP300 [nucleoplasm] (R-HSA-3899306)	0.499	2
UniProt:P35583 Foxa2	1	Foxa2 [nucleoplasm] (R-MMU-187321)	0.499	5
UniProt:P40337 VHL	3	VHL [cytosol] (R-HSA-391423) VHL [nucleoplasm] (R-HSA-1234127) monoSUMO1-K159,171,196-VHL [nucleoplasm] (R-HSA-4551697)	0.499	3
UniProt:P63166 Sumo1	8	lysyl-G97-Sumo1 [cytosol] (R-MMU-9762259) lysyl-G97-Sumo1 [nucleoplasm] (R-MMU-9762260) Ube2i-G97-Sumo1 [nucleoplasm] (R-MMU-3730634) Sumo1 [cytosol] (R-MMU-4656941) Sumo1 [nucleoplasm] (R-MMU-2990831) Sumo1 [nucleoplasm] (R-MMU-877304) Sumo1 [nucleoplasm] (R-MMU-3730616) Sumo1 [nucleoplasm] (R-MMU-3730622)	0.463	6

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