Reactome | MCC:APC/C complex [cytosol]

MCC:APC/C complex [cytosol]

Stable Identifier

R-MMU-141410

Type

Complex

Species

Mus musculus

Compartment

cytosol

Locations in the PathwayBrowser

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

Mitotic checkpoint complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)

Participates

as an output of

Degradation of multiubiquitinated Nek2A (Mus musculus)
Degradation multiubiquitinated Cyclin A (Mus musculus)
Binding of the MCC complex to the APC/C complex (Mus musculus)

as an input of

Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 (Mus musculus)
Association of Nek2A with MCC:APC/C (Mus musculus)
Association of Cyclin A with the APC/C (Mus musculus)

as a component of

Nek2A:MCC:APC/C complex [cytosol] (Mus musculus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Mus musculus)

Inferred From

MCC:APC/C complex [cytosol] (Homo sapiens)