Reactome | 14-3-3 theta [cytosol]

14-3-3 theta [cytosol]

Stable Identifier

R-MMU-1445117

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

14-3-3 protein theta, Ywhaq, 1433T_MOUSE, Ywhaq

Locations in the PathwayBrowser

Expand all

Cell Cycle (Mus musculus)

- Cell Cycle Checkpoints (Mus musculus)
  - G2/M Checkpoints (Mus musculus)
    - G2/M DNA damage checkpoint (Mus musculus)
      - Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Mus musculus)
        
        Association of p-S216-CDC25C with 14-3-3 proteins (Mus musculus)
        
        14-3-3 dimer [cytosol] (Mus musculus)
        
        14-3-3 theta dimer [cytosol] (Mus musculus)
        
        14-3-3 theta [cytosol] (Mus musculus)
        
        p-S216-CDC25C:14-3-3 protein complex [cytosol] (Mus musculus)
        
        14-3-3 dimer [cytosol] (Mus musculus)
        
        14-3-3 theta dimer [cytosol] (Mus musculus)
        
        14-3-3 theta [cytosol] (Mus musculus)

Signal Transduction (Mus musculus)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Mus musculus)
  - Signaling by Rho GTPases (Mus musculus)
    - RHO GTPase Effectors (Mus musculus)
      - RHO GTPases activate PKNs (Mus musculus)
        
        Association of p-S216-CDC25C with 14-3-3 proteins (Mus musculus)
        
        14-3-3 dimer [cytosol] (Mus musculus)
        
        14-3-3 theta dimer [cytosol] (Mus musculus)
        
        14-3-3 theta [cytosol] (Mus musculus)
        
        p-S216-CDC25C:14-3-3 protein complex [cytosol] (Mus musculus)
        
        14-3-3 dimer [cytosol] (Mus musculus)
        
        14-3-3 theta dimer [cytosol] (Mus musculus)
        
        14-3-3 theta [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:P68254 Ywhaq

Gene Names

Ywhaq

Chain

chain:1-245

Reference Genes

BioGPS Gene:22630 Ywhaq

KEGG:mmu:22630 Ywhaq

Monarch:22630 Ywhaq

NCBI Gene:22630 Ywhaq

UCSC:P68254 Ywhaq

Reference Transcript

RefSeq:NM_011739.3 Ywhaq

Other Identifiers

10399629

1420828_s_at

1420829_a_at

1420830_x_at

1432842_s_at

1436846_x_at

1437608_x_at

1460590_s_at

1460621_x_at

17280235

17290682

22630

4379959

4510184

4528969

4585893

4637542

4760818

4807546

4940289

5413815

5570959

93016_at

97061_g_at

A_52_P308542

A_55_P2178349

A_55_P2182159

A_65_P16952

A_66_P123478

GE104366

GE119492

GO:0003824

GO:0004497

GO:0005515

GO:0005737

GO:0005829

GO:0006355

GO:0006605

GO:0007165

GO:0007264

GO:0008104

GO:0016491

GO:0019904

GO:0032991

GO:0034766

GO:0042802

GO:0044325

GO:0045184

GO:0045202

GO:0045892

GO:0071889

ILMN_2525493

Msa.2739.0_f_at

d87662_s_at

Participates

as a component of

14-3-3 theta dimer [cytosol] (Mus musculus)

Inferred From

YWHAQ [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_035869.1

ENSEMBL

ENSMUST00000103002, ENSMUST00000155480, ENSMUSP00000117118, ENSMUSG00000076432, ENSMUST00000135088, ENSMUSP00000100067, ENSMUSP00000123605

PRO

P68254

GlyGen

P68254

MGI

891963

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P23242 Gja1	7	p-S373-Gja1 [plasma membrane] (R-MMU-9857672) Gja1 [Golgi membrane] (R-MMU-190649) Gja1 [endoplasmic reticulum membrane] (R-MMU-190654) Gja1 [lysosomal membrane] (R-MMU-196173) phospho-Gja1 [plasma membrane] (R-MMU-191657) Gja1 [plasma membrane] (R-MMU-9857668) Gja1 [Golgi-associated vesicle membrane] (R-MMU-190544)	0.537	3
UniProt:Q61337 Bad	6	phospho-Bad [cytosol] (R-MMU-217297) Bad [mitochondrial outer membrane] (R-MMU-114242) p-S136-Bad [cytosol] (R-MMU-3139049) Bad [cytosol] (R-MMU-3139043) Bad [cytosol] (R-MMU-50662) phospho-Bad [cytosol] (R-MMU-198335)	0.527	4
UniProt:P08050 Gja1	10	Cx43 [plasma membrane] (R-RNO-191661) Connexin 43 [Golgi membrane] (R-RNO-190650) Cx43 [endoplasmic reticulum membrane] (R-RNO-190688) Gja1 [Golgi membrane] (R-RNO-190649) Gja1 [endoplasmic reticulum membrane] (R-RNO-190654) Gja1 [lysosomal membrane] (R-RNO-196173) phospho-Gja1 [plasma membrane] (R-RNO-191657) Gja1 [plasma membrane] (R-RNO-158058) Cx43 [Golgi-associated vesicle membrane] (R-RNO-190646) Gja1 [Golgi-associated vesicle membrane] (R-RNO-190544)	0.527	2