Reactome | Rad21 [nucleoplasm]

Rad21 [nucleoplasm]

Stable Identifier

R-MMU-163042

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

RAD21, Q61550

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Mus musculus)

- Post-translational protein modification (Mus musculus)
  - SUMOylation (Mus musculus)
    - SUMO E3 ligases SUMOylate target proteins (Mus musculus)
      - SUMOylation of DNA damage response and repair proteins (Mus musculus)
        
        SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 (Mus musculus)
        
        Cohesin Complex [nucleoplasm] (Mus musculus)
        
        Rad21 [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:Q61550 Rad21

Gene Names

Rad21, Hr21, Scc1

Chain

chain:1-635, chain:280-635

Reference Genes

BioGPS Gene:19357 Rad21

ENSEMBL:ENSMUSG00000022314.11 Rad21

KEGG Gene (Mus musculus):19357 Rad21

Monarch:19357 Rad21

NCBI Gene:19357 Rad21

UCSC:Q61550 Rad21

Reference Transcript

Other Identifiers

10428561

1416161_at

1416162_at

1455938_x_at

17316996

19357

4319304

4354203

4408058

4410483

4433205

4455113

4505613

4716164

4954929

4984931

5140132

5144552

5287672

5325107

5336946

5339367

5381685

5567141

5589581

5611531

94768_at

A_51_P384091

A_52_P39237

GE34319

GO:0000228

GO:0000278

GO:0000775

GO:0000785

GO:0000794

GO:0001666

GO:0003682

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0005829

GO:0006281

GO:0006310

GO:0006325

GO:0006351

GO:0006355

GO:0006357

GO:0006915

GO:0006974

GO:0007049

GO:0007059

GO:0007062

GO:0008278

GO:0010628

GO:0010629

GO:0010972

GO:0012501

GO:0016043

GO:0016363

GO:0030496

GO:0030892

GO:0032691

GO:0032720

GO:0032733

GO:0034351

GO:0043226

GO:0043524

GO:0045841

GO:0045876

GO:0051301

GO:0071168

GO:0106222

GO:0140014

GO:0140297

GO:0140588

GO:1990414

ILMN_2612856

d37790_s_at

mMC013330

Participates

as a component of

Other forms of this molecule

Rad21 [nucleoplasm]

Double-strand-break repair protein rad21 homolog [nucleoplasm]

phospho-Rad21 [cytosol]

phospho-Rad21 [chromosome]

Rad21 [cytosol]

phospho-Rad21 [cytosol]

Rad21 [cytosol]

Rad21 [chromosome, centromeric region]

phospho-Rad21 [chromosome, centromeric region]

Rad21 [chromosome, centromeric region]

phospho-Rad21 [chromosome, centromeric region]

Rad21 [chromosome]

Rad21 [chromosome, centromeric region]

Inferred From

RAD21 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_033035.3, XP_006520707.1, XP_006520708.1

Ensembl

ENSMUSG00000022314, ENSMUSP00000022927, ENSMUST00000022927

PRO

Q61550

MGI

108016

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9CW03 Smc3	6	SMC3 [cytosol] (R-MMU-2545223) 2xAcK-SMC3 [cytosol] (R-MMU-2484792) 2xAcK-SMC3 [chromosome] (R-MMU-2468146) 2xAcK-SMC3 [chromosome, centromeric region] (R-MMU-2468148) 2xAcK-SMC3 [nucleoplasm] (R-MMU-2468050) Structural maintenance of chromosomes protein 3 [nucleoplasm] (R-MMU-912387)	0.564	2
UniProt:Q9UQE7 SMC3	6	SMC3 [cytosol] (R-HSA-2545223) 2xAcK-SMC3 [cytosol] (R-HSA-2484792) 2xAcK-SMC3 [chromosome] (R-HSA-2468146) 2xAcK-SMC3 [chromosome, centromeric region] (R-HSA-2468148) 2xAcK-SMC3 [nucleoplasm] (R-HSA-2468050) SMC3 [nucleoplasm] (R-HSA-163009)	0.564	2
UniProt:Q29RF7 PDS5A	4	PDS5A [cytosol] (R-HSA-2484799) PDS5A [chromosome] (R-HSA-2466360) PDS5A [chromosome, centromeric region] (R-HSA-2468259) PDS5A [nucleoplasm] (R-HSA-2468043)	0.564	2
UniProt:Q14683 SMC1A	4	SMC1A [cytosol] (R-HSA-2484798) SMC1A [chromosome] (R-HSA-1638774) SMC1A [chromosome, centromeric region] (R-HSA-2466015) SMC1A [nucleoplasm] (R-HSA-64561)	0.564	2
UniProt:Q8WVM7 STAG1	4	STAG1 [cytosol] (R-HSA-2484793) STAG1 [chromosome] (R-HSA-1638773) STAG1 [nucleoplasm] (R-HSA-163016) STAG1 [chromosome, centromeric region] (R-HSA-2466017)	0.564	2