Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
TSC1:TSC2 [cytosol]
Stable Identifier
R-MMU-165175
Type
Complex
Species
Mus musculus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional Regulation by TP53 (Mus musculus)
TP53 Regulates Metabolic Genes (Mus musculus)
Formation of TSC1:TSC2 complex (Mus musculus)
TSC1:TSC2 [cytosol] (Mus musculus)
p-AMPK phosphorylates TSC1:TSC2 (Mus musculus)
TSC1:TSC2 [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
MTOR signalling (Mus musculus)
Energy dependent regulation of mTOR by LKB1-AMPK (Mus musculus)
p-AMPK phosphorylates TSC1:TSC2 (Mus musculus)
TSC1:TSC2 [cytosol] (Mus musculus)
Inhibition of TSC complex formation by PKB (Mus musculus)
Phosphorylation of complexed TSC2 by PKB (Mus musculus)
TSC1:TSC2 [cytosol] (Mus musculus)
Vesicle-mediated transport (Mus musculus)
Membrane Trafficking (Mus musculus)
Rab regulation of trafficking (Mus musculus)
TBC/RABGAPs (Mus musculus)
TBC1D7 binds the TSC1-TSC2 complex (Mus musculus)
TBC1D7:TSC1:TSC2 [cytosol] (Mus musculus)
TSC1:TSC2 [cytosol] (Mus musculus)
TSC1:TSC2 [cytosol] (Mus musculus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Tsc1 [cytosol]
(Mus musculus)
Tsc2 [cytosol]
(Mus musculus)
Participates
as an input of
TBC1D7 binds the TSC1-TSC2 complex (Mus musculus)
Phosphorylation of complexed TSC2 by PKB (Mus musculus)
p-AMPK phosphorylates TSC1:TSC2 (Mus musculus)
as a component of
TBC1D7:TSC1:TSC2 [cytosol] (Mus musculus)
as an output of
Formation of TSC1:TSC2 complex (Mus musculus)
Inferred From
TSC1:TSC2 [cytosol]
(Homo sapiens)
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text