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About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
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Rela [cytosol]
Stable Identifier
R-MMU-168172
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
RELA, Q04207
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Mus musculus)
Cellular responses to mechanical stimuli (Mus musculus)
Response of endothelial cells to shear stress (Mus musculus)
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells (Mus musculus)
PTK2 (FAK) and Gq/11 enhance the degradation of NFKBIA (IkBalpha), phosphorylation of RELA (p65) on serine-536, and translocation of p-S536-RELA:NFKB1 (p65:p50) to the nucleus (Mus musculus)
IkB(alpha):NF-kB complex [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
Immune System (Mus musculus)
Adaptive Immune System (Mus musculus)
Signaling by the B Cell Receptor (BCR) (Mus musculus)
Downstream signaling events of B Cell Receptor (BCR) (Mus musculus)
Activation of NF-kappaB in B cells (Mus musculus)
Activated IKK phosphorylates I-kappaB (Mus musculus)
NF-kappa-B p50,p65,c-Rel:IKB [cytosol] (Mus musculus)
NF-kappaB p50:p65:IKB [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappaB p65:p65:IKB [cytosol] (Mus musculus)
NF-kappaB p65:p65 [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Mus musculus)
NF-kappaB p50:p65:p-IKB [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappaB p65:p65:p-IKB [cytosol] (Mus musculus)
NF-kappaB p65:p65 [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappaB translocates from the cytosol to the nucleus (Mus musculus)
NF-kappaB p50,p65,c-Rel dimer [cytosol] (Mus musculus)
NF-kappaB p65:p65 [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
SCF with beta-TrCP1 or beta-TrCP2 binds NF-kappaB:phospho-IkB (Mus musculus)
NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Mus musculus)
NF-kappaB p50:p65:p-IKB [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappaB p65:p65:p-IKB [cytosol] (Mus musculus)
NF-kappaB p65:p65 [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappaB:p-IkB:SCF-betaTrCP [cytosol] (Mus musculus)
NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Mus musculus)
NF-kappaB p50:p65:p-IKB [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappaB p65:p65:p-IKB [cytosol] (Mus musculus)
NF-kappaB p65:p65 [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
SCF-beta-TrCP ubiquitinylates IkB (Mus musculus)
NF-kappaB p50,p65,c-Rel:ub-p-IKB [cytosol] (Mus musculus)
NF-kappaB p50:p65:ub-p-IKB [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappaB p65:p65:ub-p-IkB [cytosol] (Mus musculus)
NF-kappaB p65:p65 [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappaB:p-IkB:SCF-betaTrCP [cytosol] (Mus musculus)
NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Mus musculus)
NF-kappaB p50:p65:p-IKB [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappaB p65:p65:p-IKB [cytosol] (Mus musculus)
NF-kappaB p65:p65 [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
Ubiquitinated IkB is degraded (Mus musculus)
NF-kappaB p50,p65,c-Rel dimer [cytosol] (Mus musculus)
NF-kappaB p65:p65 [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappaB p50,p65,c-Rel:ub-p-IKB [cytosol] (Mus musculus)
NF-kappaB p50:p65:ub-p-IKB [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappaB p65:p65:ub-p-IkB [cytosol] (Mus musculus)
NF-kappaB p65:p65 [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
TCR signaling (Mus musculus)
Downstream TCR signaling (Mus musculus)
26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex (Mus musculus)
K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFKB1:RELA translocates from the cytosol to the nucleus (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex (Mus musculus)
K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
p-S32,36-IkB-alpha:NF-kB complex [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Mus musculus)
IkB(alpha):NF-kB complex [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
p-S32,36-IkB-alpha:NF-kB complex [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
Cytokine Signaling in Immune system (Mus musculus)
Signaling by Interleukins (Mus musculus)
Interleukin-1 family signaling (Mus musculus)
Interleukin-1 signaling (Mus musculus)
Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex (Mus musculus)
BTRC:CUL1:RBX1:SKP1:NFKB1:RELA:p-S32,S36-NFKBIA:Ub [cytosol] (Mus musculus)
NFKB1:RELA:p-S32,S36-NFKBIA:Ub [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFKB1(1-433):RELA:p-S32,S36-NFKBIA:BTRC:CUL1:RBX1:SKP1 [cytosol] (Mus musculus)
NFKB1(1-433):RELA:p-S32,S36-NFKBIA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFKB1:RELA translocates from the cytosol to the nucleus (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex (Mus musculus)
NFKB1(1-433):RELA:p-S32,S36-NFKBIA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFKB1(1-433):RELA:p-S32,S36-NFKBIA:BTRC:CUL1:RBX1:SKP1 [cytosol] (Mus musculus)
NFKB1(1-433):RELA:p-S32,S36-NFKBIA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFkB inhibitor:NFkB complex [cytosol] (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappa-B complex is transported from cytosol to nucleus (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappa-B inhibitor binds NF-kappa-B complex (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFkB inhibitor:NFkB complex [cytosol] (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFKB1:RELA:p-S32,S36-NFKBIA:Ub [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
Innate Immune System (Mus musculus)
C-type lectin receptors (CLRs) (Mus musculus)
CLEC7A (Dectin-1) signaling (Mus musculus)
26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex (Mus musculus)
K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFKB1:RELA translocates from the cytosol to the nucleus (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex (Mus musculus)
K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
p-S32,36-IkB-alpha:NF-kB complex [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Mus musculus)
IkB(alpha):NF-kB complex [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
p-S32,36-IkB-alpha:NF-kB complex [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
Cytosolic sensors of pathogen-associated DNA (Mus musculus)
DEx/H-box helicases activate type I IFN and inflammatory cytokines production (Mus musculus)
NFkB complex translocates from the cytosol to the nucleus (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
ZBP1(DAI) mediated induction of type I IFNs (Mus musculus)
RIP-mediated NFkB activation via ZBP1 (Mus musculus)
Active IKK Complex phosphorylates NF-kappa-B inhibitor (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFkB inhibitor:NFkB complex [cytosol] (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFkB complex translocates from the cytosol to the nucleus (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Mus musculus)
TRAF6 mediated NF-kB activation (Mus musculus)
Active IKK Complex phosphorylates NF-kappa-B inhibitor (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFkB inhibitor:NFkB complex [cytosol] (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappa-B complex is transported from cytosol to nucleus (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
Fc epsilon receptor (FCERI) signaling (Mus musculus)
FCERI mediated NF-kB activation (Mus musculus)
26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex (Mus musculus)
K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFKB1:RELA translocates from the cytosol to the nucleus (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex (Mus musculus)
K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
p-S32,36-IkB-alpha:NF-kB complex [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Mus musculus)
IkB(alpha):NF-kB complex [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
p-S32,36-IkB-alpha:NF-kB complex [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
Toll-like Receptor Cascades (Mus musculus)
Toll Like Receptor 10 (TLR10) Cascade (Mus musculus)
MyD88 cascade initiated on plasma membrane (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFkB inhibitor:NFkB complex [cytosol] (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappa-B complex is transported from cytosol to nucleus (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappa-B inhibitor binds NF-kappa-B complex (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFkB inhibitor:NFkB complex [cytosol] (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
Toll Like Receptor 2 (TLR2) Cascade (Mus musculus)
Toll Like Receptor TLR1:TLR2 Cascade (Mus musculus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFkB inhibitor:NFkB complex [cytosol] (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappa-B complex is transported from cytosol to nucleus (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappa-B inhibitor binds NF-kappa-B complex (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFkB inhibitor:NFkB complex [cytosol] (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
Toll Like Receptor TLR6:TLR2 Cascade (Mus musculus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFkB inhibitor:NFkB complex [cytosol] (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappa-B complex is transported from cytosol to nucleus (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappa-B inhibitor binds NF-kappa-B complex (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFkB inhibitor:NFkB complex [cytosol] (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
Toll Like Receptor 3 (TLR3) Cascade (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFkB inhibitor:NFkB complex [cytosol] (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappa-B complex is transported from cytosol to nucleus (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappa-B inhibitor binds NF-kappa-B complex (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFkB inhibitor:NFkB complex [cytosol] (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
Toll Like Receptor 4 (TLR4) Cascade (Mus musculus)
MyD88-independent TLR4 cascade (Mus musculus)
TRIF (TICAM1)-mediated TLR4 signaling (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFkB inhibitor:NFkB complex [cytosol] (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappa-B complex is transported from cytosol to nucleus (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappa-B inhibitor binds NF-kappa-B complex (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFkB inhibitor:NFkB complex [cytosol] (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFkB inhibitor:NFkB complex [cytosol] (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappa-B complex is transported from cytosol to nucleus (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappa-B inhibitor binds NF-kappa-B complex (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFkB inhibitor:NFkB complex [cytosol] (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
Toll Like Receptor 5 (TLR5) Cascade (Mus musculus)
MyD88 cascade initiated on plasma membrane (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFkB inhibitor:NFkB complex [cytosol] (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappa-B complex is transported from cytosol to nucleus (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappa-B inhibitor binds NF-kappa-B complex (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFkB inhibitor:NFkB complex [cytosol] (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Mus musculus)
MyD88 dependent cascade initiated on endosome (Mus musculus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFkB inhibitor:NFkB complex [cytosol] (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappa-B complex is transported from cytosol to nucleus (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappa-B inhibitor binds NF-kappa-B complex (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFkB inhibitor:NFkB complex [cytosol] (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
Toll Like Receptor 9 (TLR9) Cascade (Mus musculus)
MyD88 dependent cascade initiated on endosome (Mus musculus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFkB inhibitor:NFkB complex [cytosol] (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappa-B complex is transported from cytosol to nucleus (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kappa-B inhibitor binds NF-kappa-B complex (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFkB inhibitor:NFkB complex [cytosol] (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Death Receptor Signaling (Mus musculus)
p75 NTR receptor-mediated signalling (Mus musculus)
Regulated proteolysis of p75NTR (Mus musculus)
p75NTR ICD signals to NF-kB (Mus musculus)
NF-kB:p75NTR ICD:TRAF6 [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
p75NTR signals via NF-kB (Mus musculus)
NF-kB is activated and signals survival (Mus musculus)
IKKbeta phosphorylates IkB causing NF-kB to dissociate (Mus musculus)
IkB(alpha):NF-kB complex [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
NF-kB migrates to the nucleus and turns on transcription (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
Rela [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q04207
Gene Names
Rela
Reference Genes
BioGPS Gene:19697 Rela
ENSEMBL:ENSMUSG00000024927
ENSEMBL:ENSMUSG00000024927.9 Rela
KEGG Gene (Mus musculus):19697 Rela
Monarch:19697 Rela
NCBI Gene:19697 Rela
UCSC:Q04207 Rela
Reference Transcript
RefSeq:NM_009045.4 Rela
Other Identifiers
10460631
1419536_a_at
17356490
19697
4360678
4383135
4423006
4479267
4479509
4502736
4508715
4515351
4667256
4983098
5286944
5295711
5392487
5467998
5473897
5497104
97813_at
A_51_P385993
A_52_P186119
A_55_P1974288
A_55_P2744639
GE33555
GO:0000122
GO:0000785
GO:0000976
GO:0000977
GO:0000978
GO:0000979
GO:0000981
GO:0001223
GO:0001227
GO:0001228
GO:0001889
GO:0001942
GO:0002357
GO:0002376
GO:0002931
GO:0003677
GO:0003682
GO:0003690
GO:0003700
GO:0005515
GO:0005634
GO:0005667
GO:0005694
GO:0005737
GO:0005829
GO:0006117
GO:0006325
GO:0006351
GO:0006355
GO:0006357
GO:0006952
GO:0006954
GO:0007155
GO:0007218
GO:0007249
GO:0008092
GO:0008284
GO:0009410
GO:0009612
GO:0009617
GO:0009887
GO:0010033
GO:0010035
GO:0010224
GO:0010575
GO:0010628
GO:0012501
GO:0014040
GO:0014070
GO:0016525
GO:0019221
GO:0019899
GO:0019901
GO:0023052
GO:0030154
GO:0030163
GO:0031490
GO:0031625
GO:0032332
GO:0032495
GO:0032496
GO:0032570
GO:0032731
GO:0032735
GO:0032755
GO:0032757
GO:0032868
GO:0032991
GO:0033209
GO:0033234
GO:0033590
GO:0034097
GO:0034142
GO:0035525
GO:0035556
GO:0035729
GO:0035994
GO:0036211
GO:0038061
GO:0038084
GO:0038161
GO:0042177
GO:0042277
GO:0042301
GO:0042542
GO:0042802
GO:0042803
GO:0042805
GO:0042826
GO:0043066
GO:0043123
GO:0043200
GO:0043226
GO:0043565
GO:0044877
GO:0045087
GO:0045202
GO:0045892
GO:0045893
GO:0045944
GO:0046627
GO:0048856
GO:0050727
GO:0050862
GO:0051059
GO:0051092
GO:0051591
GO:0070301
GO:0070431
GO:0070498
GO:0070555
GO:0071159
GO:0071222
GO:0071223
GO:0071224
GO:0071316
GO:0071347
GO:0071354
GO:0071356
GO:0071532
GO:0098542
GO:0098978
GO:0099527
GO:0140110
GO:0140296
GO:0140297
GO:1901223
GO:1901224
GO:1902004
GO:1902894
GO:1902895
GO:1904385
GO:1904996
GO:2000630
GO:2001237
ILMN_2740859
M61909_s_at
mMC014195
Participates
as a component of
NFKB1:RELA:p-S32,S36-NFKBIA:Ub [cytosol] (Mus musculus)
NFKB1(1-433):RELA:p-S32,S36-NFKBIA [cytosol] (Mus musculus)
NF-kappaB p65:p65 [cytosol] (Mus musculus)
NFKB1(1-433):RELA [cytosol] (Mus musculus)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Mus musculus)
Other forms of this molecule
Rela [nucleoplasm]
phospho-Rela [nucleoplasm]
phospho-Rela [nucleoplasm]
Rela [nucleoplasm]
Rela [nucleoplasm]
phospho-Rela [nucleoplasm]
Inferred From
RELA [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_033071.1
Ensembl
ENSMUSP00000025867
,
ENSMUSG00000024927
,
ENSMUST00000025867
PRO
Q04207
MGI
103290
PDB
1LE9
,
2LWW
,
1OY3
,
9BDV
,
1BFT
,
1MY5
,
9BDU
,
1MY7
,
1LE5
,
1IKN
,
1RAM
,
5U01
,
2I9T
,
1LEI
,
2RAM
,
6GGR
,
1K3Z
,
9BDX
,
1VKX
,
9BDW
Interactors (20)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9Z1E3
6
Nfkbia [cytosol]
(R-MMU-6782960)
Nfkbia [nucleoplasm]
(R-MMU-4656935)
Nfkbia [nucleoplasm]
(R-MMU-4656929)
phospho-Nfkbia [cytosol]
(R-MMU-1168581)
phospho-Nfkbia [cytosol]
(R-MMU-177677)
Nfkbia [cytosol]
(R-MMU-168151)
0.912
9
UniProt:P25799
8
Nfkb1 [specific granule lumen]
(R-MMU-6799557)
Nfkb1 [extracellular region]
(R-MMU-6806304)
Nfkb1 [secretory granule lumen]
(R-MMU-6801004)
phospho-Nfkb1 [cytosol]
(R-MMU-451619)
phospho-Nfkb1 [cytosol]
(R-MMU-451611)
Nfkb1 [cytosol]
(R-MMU-451607)
Nfkb1 [nucleoplasm]
(R-MMU-177655)
Nfkb1 [cytosol]
(R-MMU-168168)
0.844
7
UniProt:P45481 Crebbp
4
CREBBP [nucleoplasm]
(R-MMU-193545)
Crebbp [nucleoplasm]
(R-MMU-556795)
Foxo4-S-S-Crebbp [nucleoplasm]
(R-MMU-9617719)
monoSumo1-K999,K1034,K1057-Crebbp [nucleoplasm]
(R-MMU-3927936)
0.821
10
UniProt:P25799-1 NFKB1
0.77
6
UniProt:Q60778
3
phospho-Nfkbib [cytosol]
(R-MMU-1168571)
phospho-Nfkbib [cytosol]
(R-MMU-177670)
Nfkbib [cytosol]
(R-MMU-168132)
0.693
12
UniProt:Q9H9B1 EHMT1
1
EHMT1 [nucleoplasm]
(R-HSA-1183226)
0.675
5
UniProt:Q8VCD5 Med17
2
Med17 [nucleoplasm]
(R-MMU-556809)
Med17 [nucleoplasm]
(R-MMU-212401)
0.632
4
UniProt:Q9WTK5
6
Nfkb2 [cytosol]
(R-MMU-4755500)
Nfkb2 [cytosol]
(R-MMU-2677931)
phospho-Nfkb2 [cytosol]
(R-MMU-5607636)
phospho-Nfkb2 [cytosol]
(R-MMU-5607629)
Nfkb2 [cytosol]
(R-MMU-168144)
Nfkb2 [nucleoplasm]
(R-MMU-177674)
0.613
3
UniProt:Q04207
7
Rela [nucleoplasm]
(R-MMU-8865233)
phospho-Rela [nucleoplasm]
(R-MMU-9861499)
phospho-Rela [nucleoplasm]
(R-MMU-5660642)
Rela [nucleoplasm]
(R-MMU-177676)
Rela [cytosol]
(R-MMU-168172)
Rela [nucleoplasm]
(R-MMU-4755466)
phospho-Rela [nucleoplasm]
(R-MMU-5624468)
0.607
2
UniProt:P25799-PRO_0000030313 NFKB1
0.597
4
UniProt:P25963 NFKBIA
9
PolyUb-NFKBIA [cytosol]
(R-HSA-6782960)
NFKBIA [cytosol]
(R-HSA-168151)
p-S32,S36-NFKBIA [cytosol]
(R-HSA-177677)
Ub-K21,22-p-S32,S36-NFKBIA [cytosol]
(R-HSA-1168581)
NFKBIA [nucleoplasm]
(R-HSA-4656929)
monoSUMO1-K21-NFKBIA [nucleoplasm]
(R-HSA-4656935)
NFKBIA S32I [cytosol]
(R-HSA-5228846)
NFKBIA F2_M37del [cytosol]
(R-HSA-9630119)
NFKBIA M37K [cytosol]
(R-HSA-5228805)
0.589
2
UniProt:Q8TBK2 SETD6
1
SETD6 [nucleoplasm]
(R-HSA-8865234)
0.558
4
UniProt:Q62227
1
Nr0b2 [nucleoplasm]
(R-MMU-376312)
0.537
3
UniProt:P29477
2
NOS2 [peroxisomal matrix]
(R-MMU-9033124)
NOS2 [cytosol]
(R-MMU-202107)
0.524
3
UniProt:P25799-PRO_0000030312 NFKB1
0.499
3
UniProt:O09106 Hdac1
2
Hdac1 [nucleoplasm]
(R-MMU-4616030)
Hdac1 [nucleoplasm]
(R-MMU-573340)
0.499
2
IntAct:EBI-1209243 Q9WTK5-PRO
0.499
3
UniProt:P12813
2
phospho-Nr4a1 [nucleoplasm]
(R-MMU-199846)
Nr4a1 [nucleoplasm]
(R-MMU-199831)
0.499
2
UniProt:Q02248 Ctnnb1
14
phospho-Ctnnb1 [cytosol]
(R-MMU-3134933)
phospho-Ctnnb1 [nucleoplasm]
(R-MMU-3134926)
Ctnnb1 [plasma membrane]
(R-MMU-9761458)
Ctnnb1 [plasma membrane]
(R-MMU-9038440)
Ctnnb1 [nucleoplasm]
(R-MMU-3451168)
Ctnnb1 [cytosol]
(R-MMU-448839)
Ctnnb1 [cytosol]
(R-MMU-202930)
Ctnnb1 [cytosol]
(R-MMU-202950)
Ctnnb1 [nucleoplasm]
(R-MMU-9735212)
phospho-Ctnnb1 [cytosol]
(R-MMU-8942374)
beta-catenin [cytosol]
(R-MMU-206225)
phospho-Ctnnb1 [cytosol]
(R-MMU-8942369)
phospho-Ctnnb1 [cytosol]
(R-MMU-8942367)
phospho-Ctnnb1 [cytosol]
(R-MMU-8942363)
0.499
5
UniProt:P70338 Gfi1
1
Gfi1 [nucleoplasm]
(R-MMU-9634440)
0.463
3
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