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CDK1 [cytosol]
Stable Identifier
R-MMU-170075
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
P11440
Locations in the PathwayBrowser for interactor UniProt:P22674 CCNO
Expand all
Cell Cycle (Mus musculus)
Cell Cycle, Mitotic (Mus musculus)
Mitotic G2-G2/M phases (Mus musculus)
G2/M Transition (Mus musculus)
Cyclin A/B1/B2 associated events during G2/M transition (Mus musculus)
Formation of Cyclin A:Cdc2 complexes (Mus musculus)
CDK1 [cytosol] (Mus musculus)
Formation of Cyclin B:Cdc2 complexes (Mus musculus)
CDK1 [cytosol] (Mus musculus)
Immune System (Mus musculus)
Cytokine Signaling in Immune system (Mus musculus)
Interferon Signaling (Mus musculus)
Antiviral mechanism by IFN-stimulated genes (Mus musculus)
PKR-mediated signaling (Mus musculus)
p-PKR dimer phosphorylates CDK1 (Mus musculus)
CDK1 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:P11440 Cdk1
Gene Names
Cdk1, Cdc2, Cdc2a, Cdkn1
Chain
chain:1-297
Reference Genes
BioGPS Gene:12534 Cdk1
ENSEMBL:ENSMUSG00000019942.14 Cdk1
KEGG Gene (Mus musculus):12534 Cdk1
Monarch:12534 Cdk1
NCBI Gene:12534 Cdk1
UCSC:P11440 Cdk1
Reference Transcript
RefSeq:NM_007659.3 Cdk1
Other Identifiers
100128_at
10369815
12534
1448314_at
17241692
4472993
4588721
4720947
4881487
4934166
5093482
5121588
5251273
5275259
5480188
5511184
5551219
5556695
A_52_P339954
A_55_P2016647
A_55_P2016652
A_55_P2048588
A_66_P105123
GE1469937
GE33489
GO:0000082
GO:0000086
GO:0000166
GO:0000278
GO:0000307
GO:0003682
GO:0003824
GO:0004672
GO:0004674
GO:0004693
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0005759
GO:0005813
GO:0005815
GO:0005819
GO:0005829
GO:0005856
GO:0005876
GO:0006091
GO:0006260
GO:0006325
GO:0006338
GO:0006351
GO:0006355
GO:0006357
GO:0006468
GO:0006886
GO:0006913
GO:0006915
GO:0007010
GO:0007049
GO:0007059
GO:0007095
GO:0008353
GO:0009410
GO:0009636
GO:0010243
GO:0010628
GO:0010629
GO:0010971
GO:0012501
GO:0014070
GO:0014075
GO:0014823
GO:0016301
GO:0016310
GO:0016740
GO:0018105
GO:0018107
GO:0023052
GO:0030154
GO:0030261
GO:0030332
GO:0030496
GO:0030544
GO:0030855
GO:0031100
GO:0034501
GO:0035173
GO:0036211
GO:0042307
GO:0042542
GO:0042752
GO:0043066
GO:0043226
GO:0044772
GO:0045471
GO:0045740
GO:0045931
GO:0046686
GO:0046688
GO:0048144
GO:0048511
GO:0048678
GO:0048856
GO:0051301
GO:0055015
GO:0060045
GO:0062033
GO:0065003
GO:0070301
GO:0071407
GO:0072686
GO:0090166
GO:0097122
GO:0097125
GO:0097472
GO:0106310
GO:0140014
GO:0140096
GO:1900182
GO:1902850
GO:1905448
ILMN_2657844
ILMN_2698252
ILMN_2961747
Msa.18569.0_s_at
mMC016053
u58633_s_at
Participates
as a component of
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
mother centriole [cytosol] (Mus musculus)
Nlp-depleted centrosome [cytosol] (Mus musculus)
centrosome containing phosphorylated Nlp [cytosol] (Mus musculus)
cNAP-1 depleted centrosome [cytosol] (Mus musculus)
CCNB1:CDK1 [cytosol] (Mus musculus)
CCNA:CDK1 [cytosol] (Mus musculus)
CCNB:CDK1 [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
as an input of
p-PKR dimer phosphorylates CDK1 (Mus musculus)
Formation of Cyclin A:Cdc2 complexes (Mus musculus)
Formation of Cyclin B:Cdc2 complexes (Mus musculus)
Other forms of this molecule
phospho-p-T161-CDK1 [nucleoplasm]
phospho-p-T14,Y15,T161-CDK1 [nucleoplasm]
phospho-p-T161-CDK1 [cytosol]
phospho-p-T14,Y15,T161-CDK1 [cytosol]
phospho-p-T14-CDK1 [cytosol]
phospho-p-T14-CDK1 [nucleoplasm]
Cdk1 [nucleoplasm]
phospho-p-T14,T161-CDK1 [nucleoplasm]
phospho-p-Y4-CDK1 [cytosol]
CDK1 [endoplasmic reticulum membrane]
Inferred From
CDK1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_031685.2
IntEnz
2.7.11.22
ZINC - Substances
CDK1_MOUSE
ZINC target
P11440
Ensembl
ENSMUSG00000019942
,
ENSMUSP00000113184
,
ENSMUSP00000020099
,
ENSMUST00000020099
,
ENSMUST00000119827
ZINC - Biogenic
CDK1_MOUSE
PRO
P11440
MGI
88351
ZINC - Predictions - Purchasable
CDK1_MOUSE
Interactors (17)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P14635 CCNB1
4
CCNB1 [nucleoplasm]
(R-HSA-68901)
p-4S-CCNB1 [cytosol]
(R-HSA-170058)
p-4S-CCNB1 [nucleoplasm]
(R-HSA-170049)
CCNB1 [cytosol]
(R-HSA-157451)
0.623
4
UniProt:P20248 CCNA2
3
PolyUb-CCNA2 [nucleoplasm]
(R-HSA-6783099)
CCNA2 [cytosol]
(R-HSA-157444)
CCNA2 [nucleoplasm]
(R-HSA-68905)
0.623
4
UniProt:P63208 SKP1
2
SKP1 [nucleoplasm]
(R-HSA-187538)
SKP1 [cytosol]
(R-HSA-174150)
0.623
3
UniProt:Q13309 SKP2
3
SKP2 [cytosol]
(R-HSA-975495)
PolyUb-SKP2 [nucleoplasm]
(R-HSA-9687073)
SKP2 [nucleoplasm]
(R-HSA-975554)
0.623
4
UniProt:O95067 CCNB2
1
CCNB2 [cytosol]
(R-HSA-68897)
0.623
4
UniProt:P33552 CKS2
0.623
4
UniProt:P61024 CKS1B
1
CKS1B [nucleoplasm]
(R-HSA-187533)
0.623
4
UniProt:P20263 Pou5f1
2
Pou5f1 [nucleoplasm]
(R-MMU-3245981)
POU5F1 [nucleoplasm]
(R-MMU-452472)
0.61
4
UniProt:Q61457
2
Ccne1 [cytosol]
(R-MMU-157443)
Ccne1 [nucleoplasm]
(R-MMU-68363)
0.589
3
UniProt:Q99640 PKMYT1
3
PKMYT1 [cytosol]
(R-HSA-157457)
p-PKMYT1 [nucleoplasm]
(R-HSA-162650)
PKMYT1 [nucleoplasm]
(R-HSA-74386)
0.564
3
UniProt:Q9UJX3 ANAPC7
2
ANAPC7 [nucleoplasm]
(R-HSA-174204)
ANAPC7 [cytosol]
(R-HSA-174242)
0.499
2
UniProt:Q8IVT2 MISP
0.499
2
UniProt:P22674 CCNO
0.499
2
UniProt:Q14204 DYNC1H1
3
DYNC1H1 [extracellular region]
(R-HSA-6806223)
DYNC1H1 [azurophil granule lumen]
(R-HSA-6799155)
DYNC1H1 [cytosol]
(R-HSA-380285)
0.499
2
UniProt:O43175 PHGDH
1
PHGDH [cytosol]
(R-HSA-977340)
0.499
2
UniProt:P46527 CDKN1B
8
p-S10 CDKN1B [cytosol]
(R-HSA-9632829)
p-S10 CDKN1B [nucleoplasm]
(R-HSA-9632832)
p-T157-CDKN1B [cytosol]
(R-HSA-198629)
CDKN1B [cytosol]
(R-HSA-198622)
p-Y88-CDKN1B [cytosol]
(R-HSA-8848438)
p-Y88-CDKN1B [nucleoplasm]
(R-HSA-8942808)
p-T187-CDKN1B [nucleoplasm]
(R-HSA-187525)
CDKN1B [nucleoplasm]
(R-HSA-182563)
0.499
2
UniProt:Q14674 ESPL1
4
ESPL1(1-1506) [cytosol]
(R-HSA-2467768)
ESPL1(1507-1535) [cytosol]
(R-HSA-2500272)
ESPL1(1536-2120) [cytosol]
(R-HSA-2467767)
ESPL1 [cytosol]
(R-HSA-1638167)
0.499
2
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